Search Results - "Albers, Eva"
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Metabolic characteristics and importance of the universal methionine salvage pathway recycling methionine from 5′‐methylthioadenosine
Published in IUBMB life (01-12-2009)“…The methionine salvage pathway, also called the 5′‐methylthioadenosine (MTA) cycle, recycles the sulfur of MTA, which is a by‐product in the biosyntheses of…”
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Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication
Published in PLoS biology (01-07-2013)“…Reciprocal interactions between neurons and oligodendrocytes are not only crucial for myelination, but also for long-term survival of axons. Degeneration of…”
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Extracellular vesicles: interneural shuttles of complex messages
Published in Current opinion in neurobiology (01-08-2016)“…Highlights • Extracellular vesicles (EVs) deliver a set of biomolecules including regulatory RNAs and proteins between neural cells. • EVs are suggested to…”
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Mechanisms of axonal support by oligodendrocyte-derived extracellular vesicles
Published in Nature reviews. Neuroscience (01-08-2023)“…Extracellular vesicles (EVs) have recently emerged as versatile elements of cell communication in the nervous system, mediating tissue homeostasis. EVs…”
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Extracellular Vesicles at CNS barriers: Mode of action
Published in Current opinion in neurobiology (01-08-2022)“…The exchange of molecules between the brain and periphery is limited by cellular barriers such as the blood–brain barrier (BBB) and the blood-CSF barrier…”
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Platelets, endothelial cells and leukocytes contribute to the exercise-triggered release of extracellular vesicles into the circulation
Published in Journal of extracellular vesicles (01-12-2019)“…Physical activity initiates a wide range of multi-systemic adaptations that promote mental and physical health. Recent work demonstrated that exercise triggers…”
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Oligodendrocytes support axonal transport and maintenance via exosome secretion
Published in PLoS biology (22-12-2020)“…Neurons extend long axons that require maintenance and are susceptible to degeneration. Long-term integrity of axons depends on intrinsic mechanisms including…”
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Extracellular vesicles in the oligodendrocyte microenvironment
Published in Neuroscience letters (23-04-2020)“…•Extracellular vesicles released by oligodendrocytes (OL-EVs) are internalized by microglia and neurons.•OL-EVs mediate homeostatic maintenance within the…”
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Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain
Published in Cell metabolism (04-08-2020)“…An evolutionarily conserved function of glia is to provide metabolic and structural support for neurons. To identify molecules generated by glia and with vital…”
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Superfood for axons: Glial exosomes boost axonal energetics by delivery of SIRT2
Published in Neuron (Cambridge, Mass.) (03-11-2021)“…Axon integrity depends on support by glia facilitating axonal maintenance and energy homeostasis, but the molecular mechanisms are not well understood. In this…”
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Physical exercise induces rapid release of small extracellular vesicles into the circulation
Published in Journal of extracellular vesicles (01-01-2015)“…Cells secrete extracellular vesicles (EVs) by default and in response to diverse stimuli for the purpose of cell communication and tissue homeostasis. EVs are…”
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Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (26-09-2014)“…Exosomes are small membranous vesicles of endocytic origin that are released by almost every cell type. They exert versatile functions in intercellular…”
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Extracellular vesicles as mediators of neuron-glia communication
Published in Frontiers in cellular neuroscience (30-10-2013)“…In the nervous system, glia cells maintain homeostasis, synthesize myelin, provide metabolic support, and participate in immune defense. The communication…”
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From axon–glial signalling to myelination: the integrating role of oligodendroglial Fyn kinase
Published in Cellular and molecular life sciences : CMLS (01-06-2011)“…Central nervous system myelination requires recognition and signalling processes between neuronal axons and oligodendrocytes. Complex cellular rearrangements…”
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Extracellular Vesicles in neural cell interaction and CNS homeostasis
Published in FASEB bioAdvances (01-08-2021)“…Central nervous system (CNS) homeostasis critically depends on the interaction between neurons and glia cells. Extracellular vesicles (EVs) recently emerged as…”
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Emerging roles of exosomes in neuron-glia communication
Published in Frontiers in physiology (01-01-2012)“…Brain function depends on coordinated interactions between neurons and glial cells. Recent evidence indicates that these cells release endosome-derived…”
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Emerging roles of extracellular vesicles in the nervous system
Published in The Journal of neuroscience (12-11-2014)“…Information exchange executed by extracellular vesicles, including exosomes, is a newly described form of intercellular communication important in the…”
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Exosomes deliver ROS for regeneration
Published in Nature cell biology (01-03-2018)“…Inflammation and reactive oxygen species (ROS) production after central nervous system injury are thought to enhance tissue damage and hamper neuronal…”
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Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles
Published in Nature communications (27-09-2021)“…Primary cilia are microtubule based sensory organelles important for receiving and processing cellular signals. Recent studies have shown that cilia also…”
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Extracellular Vesicle-Mediated Neuron-Glia Communications in the Central Nervous System
Published in The Journal of neuroscience (02-10-2024)“…Communication between neurons and glia significantly influences the development maturation, plasticity, and disease progressions of the nervous system. As a…”
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