Search Results - "Albers, Dan"
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BNT162b2 booster after heterologous prime-boost vaccination induces potent neutralizing antibodies and T cell reactivity against SARS-CoV-2 Omicron BA.1 in young adults
Published in Frontiers in immunology (25-07-2022)“…In light of the decreasing immune protection against symptomatic SARS-CoV-2 infection after initial vaccinations and the now dominant immune-evasive Omicron…”
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Virucidal activity of SARS-CoV-2 rapid antigen extraction buffers
Published in Journal of clinical virology (01-02-2022)“…Since diagnostic sampling material must be considered as infectious, we evaluated whether extraction buffers of SARS-CoV-2 rapid antigen test kits may…”
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Inhibitors of Activin Receptor-like Kinase 5 Interfere with SARS-CoV-2 S-Protein Processing and Spike-Mediated Cell Fusion via Attenuation of Furin Expression
Published in Viruses (15-06-2022)“…Screening of a protein kinase inhibitor library identified SB431542, targeting activin receptor-like kinase 5 (ALK5), as a compound interfering with SARS-CoV-2…”
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SARS-CoV-2 vaccination of convalescents boosts neutralization capacity against Omicron subvariants BA.1, BA.2 and BA.5 and can be predicted by anti-S antibody concentrations in serological assays
Published in Frontiers in immunology (25-04-2023)“…Recent data on immune evasion of new SARS-CoV-2 variants raise concerns about the efficacy of antibody-based COVID-19 therapies. Therefore, in this study the…”
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Lipopolysaccharide-induced sepsis-like state compromises post-ischemic neurological recovery, brain tissue survival and remodeling via mechanisms involving microvascular thrombosis and brain T cell infiltration
Published in Brain, behavior, and immunity (01-01-2021)“…•Intraperitoneal administration of LPS exacerbates stroke-associated neurological deficits.•High dose of LPS augments infarct and atrophy volume in the…”
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ACE2-EGFR-MAPK signaling contributes to SARS-CoV-2 infection
Published in Life science alliance (01-09-2023)“…SARS-CoV-2 triggered the most severe pandemic of recent times. To enter into a host cell, SARS-CoV-2 binds to the angiotensin-converting enzyme 2 (ACE2)…”
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Development of N-Terminally Modified Variants of the CXCR4-Antagonistic Peptide EPI-X4 for Enhanced Plasma Stability
Published in Journal of medicinal chemistry (23-11-2023)“…EPI-X4, a natural peptide CXCR4 antagonist, shows potential for treating inflammation and cancer, but its short plasma stability limits its clinical…”
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Fatty acid conjugated EPI-X4 derivatives with increased activity and in vivo stability
Published in Journal of controlled release (01-09-2024)“…Dysregulation of the CXCL12/CXCR4 axis is implicated in autoimmune, inflammatory, and oncogenic diseases, positioning CXCR4 as a pivotal therapeutic target. We…”
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Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens
Published in Nature microbiology (01-04-2024)“…Some viruses are rarely transmitted orally or sexually despite their presence in saliva, breast milk, or semen. We previously identified that extracellular…”
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