Search Results - "Alberico, Stephanie"
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Optogenetic Stimulation of Frontal D1 Neurons Compensates for Impaired Temporal Control of Action in Dopamine-Depleted Mice
Published in Current biology (09-01-2017)“…Disrupted mesocortical dopamine contributes to cognitive symptoms of Parkinson’s disease (PD). Past work has implicated medial frontal neurons expressing D1…”
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Substantia Nigra Pars Reticulata Projections to the Pedunculopontine Nucleus Modulate Dyskinesia
Published in Movement disorders (01-10-2023)“…Long-term use of levodopa for Parkinson's disease (PD) treatment is often hindered by development of motor complications, including levodopa-induced dyskinesia…”
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3
Phase-adaptive brain stimulation of striatal D1 medium spiny neurons in dopamine-depleted mice
Published in Scientific reports (16-12-2022)“…Brain rhythms are strongly linked with behavior, and abnormal rhythms can signify pathophysiology. For instance, the basal ganglia exhibit a wide range of…”
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4
Dorsal Raphe Serotonin Neurons Mediate CO2-Induced Arousal from Sleep
Published in The Journal of neuroscience (21-02-2018)“…Arousal from sleep in response to CO 2 is a critical protective phenomenon. Dysregulation of CO 2 -induced arousal contributes to morbidity and mortality from…”
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5
Axial levodopa-induced dyskinesias and neuronal activity in the dorsal striatum
Published in Neuroscience (20-02-2017)“…Highlights • We developed an automated system to track levodopa-induced dyskinesias in mice. • Striatal medium spiny neurons and fast spiking interneurons were…”
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The vulnerable ventral tegmental area in Parkinson’s disease
Published in Basal ganglia (01-08-2015)“…•We ran a literature review on degeneration of the VTA in PD and added new cases.•The literature unequivocally demonstrates that the VTA is involved in PD.•Our…”
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Dorsal Raphe Serotonin Neurons Mediate CO 2 -Induced Arousal from Sleep
Published in The Journal of neuroscience (21-02-2018)“…Arousal from sleep in response to CO is a critical protective phenomenon. Dysregulation of CO -induced arousal contributes to morbidity and mortality from…”
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8
In vitro and in vivo optimization of infrared laser treatment for injured peripheral nerves
Published in Lasers in surgery and medicine (01-01-2014)“…Background and Objective Repair of peripheral nerve injuries remains a major challenge in restorative medicine. Effective therapies that can be used in…”
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9
Linear Predictive Approaches Separate Field Potentials in Animal Model of Parkinson's Disease
Published in Frontiers in neuroscience (24-04-2020)“…Parkinson's disease (PD) causes impaired movement and cognition. PD can involve profound changes in cortical and subcortical brain activity as measured by…”
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10
Organic light emitting diode improves diabetic cutaneous wound healing in rats
Published in Wound repair and regeneration (01-01-2015)“…ABSTRACT A major complication for diabetic patients is chronic wounds due to impaired wound healing. It is well documented that visible red wavelengths can…”
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Pulsed Light Irradiation Improves Behavioral Outcome in a Rat Model of Chronic Mild Stress
Published in Lasers in surgery and medicine (01-03-2012)“…Background and Objective Transcranial laser therapy (TLT) has been used successfully for the treatment of stroke in animal models and clinical trials. These…”
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12
Optogenetic approaches to evaluate striatal function in animal models of Parkinson disease
Published in Dialogues in clinical neuroscience (01-03-2016)“…Optogenetics refers to the ability to control cells that have been genetically modified to express light-sensitive ion channels. The introduction of…”
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New therapeutic strategies targeting D1-type dopamine receptors for neuropsychiatric disease
Published in Frontiers in biology (01-06-2015)“…The neurotransmitter dopamine acts via two major classes of receptors, Dl-type and D2-type. D1 receptors are highly expressed in the striatum and can also be…”
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14
Substantia nigra pars reticulata projections to the pedunculopontine nucleus modulates dyskinesia
Published in Movement disorders (17-07-2023)Get full text
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15
Regulator of G Protein Signaling 6 (RGS6) Protects Against Neurodegeneration and Motor Dysfunction in the Unilateral 6‐hydroxydopamine (6‐OHDA) mouse model of Parkinson's Disease
Published in The FASEB journal (01-04-2016)“…Abstract only PD is a devastating, and currently untreatable, neurological disease resulting from death of a subset of dopamine (DA) neurons in the substantia…”
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Dorsal Raphe Serotonin Neurons Mediate CO^sub 2^^sup -^Induced Arousal from Sleep
Published in The Journal of neuroscience (21-02-2018)“…Arousal from sleep in response to CO2 is a critical protective phenomenon. Dysregulation of CO2-induced arousal contributes to morbidity and mortality from…”
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Journal Article -
17
Prefrontal D1 dopamine signaling is necessary for temporal expectation during reaction time performance
Published in Neuroscience (26-12-2013)“…Highlights • Prefrontal dopamine signaling is involved in temporal expectation during a simple reaction time task. • VTA dopamine depletion did not change…”
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Age-dependent nigral dopaminergic neurodegeneration and α-synuclein accumulation in RGS6-deficient mice
Published in JCI insight (11-07-2019)“…Parkinson's is primarily a non-familial, age-related disorder caused by α-synuclein accumulation and the progressive loss of dopamine neurons in the substantia…”
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Striatal Neurons in the Development of Levodopa-Induced Dyskinesias in Parkinson's Disease
Published 2017“…Levodopa-induced dyskinesias (LIDs) are abnormal involuntary movements that limit the effectiveness of treatments for Parkinson's disease. Although dyskinesias…”
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Dissertation