Search Results - "Alber, Andrea B"
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Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions
Published in Molecular systems biology (01-09-2019)“…SOX2 and OCT4 are pioneer transcription factors playing a key role in embryonic stem (ES) cell self‐renewal and differentiation. How temporal fluctuations in…”
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Mitotic chromosome binding predicts transcription factor properties in interphase
Published in Nature communications (30-01-2019)“…Mammalian transcription factors (TFs) differ broadly in their nuclear mobility and sequence-specific/non-specific DNA binding. How these properties affect…”
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3
Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme
Published in Nature communications (13-06-2023)“…While the generation of many lineages from pluripotent stem cells has resulted in basic discoveries and clinical trials, the derivation of tissue-specific…”
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Derivation of Thyroid Follicular Cells From Pluripotent Stem Cells: Insights From Development and Implications for Regenerative Medicine
Published in Frontiers in endocrinology (Lausanne) (20-04-2021)“…Stem cell-based therapies to reconstitute organ function hold great promise for future clinical applications to a variety of diseases. Hypothyroidism resulting…”
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Novel FOXF1-Stabilizing Compound TanFe Stimulates Lung Angiogenesis in Alveolar Capillary Dysplasia
Published in American journal of respiratory and critical care medicine (15-04-2023)“…Alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV) is linked to heterozygous mutations in the (Forkhead Box F1) gene, a key…”
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Derivation of transplantable human thyroid follicular epithelial cells from induced pluripotent stem cells
Published in Stem cell reports (01-11-2024)“…The production of mature functioning thyroid follicular cells (TFCs) from human induced pluripotent stem cells (iPSCs) is critical for potential novel…”
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Generating 3D Spheres and 2D Air-Liquid Interface Cultures of Human Induced Pluripotent Stem Cell-Derived Type 2 Alveolar Epithelial Cells
Published in Journal of visualized experiments (15-04-2022)“…In the lung, the alveolar epithelium is a physical barrier from environmental stimuli and plays an essential role in homeostasis and disease. Type 2 alveolar…”
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8
Endogenous fluctuations of OCT 4 and SOX 2 bias pluripotent cell fate decisions
Published in Molecular systems biology (01-09-2019)“…SOX2 and OCT4 are pioneer transcription factors playing a key role in embryonic stem (ES) cell self‐renewal and differentiation. How temporal fluctuations in…”
Get full text
Journal Article