Search Results - "Albekairi, Thamer H"

The natural breakthrough: phytochemicals as potent therapeutic agents against spinocerebellar ataxia type 3 by Naveed, Muhammad, Ali, Nouman, Aziz, Tariq, Hanif, Nimra, Fatima, Mahnoor, Ali, Imran, Alharbi, Metab, Alasmari, Abdullah F., Albekairi, Thamer H.

“…There is no FDA-approved drug for neurological disorders like spinocerebellar ataxia type 3. CAG repeats mutation in the ATXN3 gene, causing spinocerebellar…”
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Neuroinflammation and Its Impact on the Pathogenesis of COVID-19 by Almutairi, Mohammed M, Sivandzade, Farzane, Albekairi, Thamer H, Alqahtani, Faleh, Cucullo, Luca

“…Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The clinical…”
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Development and immunological evaluation of an mRNA-based vaccine targeting Naegleria fowleri for the treatment of primary amoebic meningoencephalitis by Naveed, Muhammad, Ali, Urooj, Aziz, Tariq, Jabeen, Khizra, Arif, Muhammad Hammad, Alharbi, Metab, Alasmari, Abdullah F., Albekairi, Thamer H.

“…More than 95% of patients fall victim to primary amoebic meningoencephalitis (PAM), a fatal disease attacking the central nervous system. Naegleria fowleri , a…”
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Immobilization of Aspergillus oryzae tyrosine hydroxylase on ZnO nanocrystals for improved stability and catalytic efficiency towards L-dopa production by Khalid, Ansa, Ali, Sikander, Rukhma, Jahangeer, Muhammad, Sarwar, Abid, Nelofer, Rubina, Aziz, Tariq, Alharbi, Metab, Alasmari, Abdullah F., Albekairi, Thamer H.

“…The current study focuses on the submerged fermentation of tyrosine hydroxylase (TH) from  Aspergillus oryzae  IIB-9 and its immobilization on zinc oxide…”
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Molecular identification of Proteus mirabilis, Vibrio species leading to CRISPR-Cas9 modification of tcpA and UreC genes causing cholera and UTI by Naveed, Muhammad, Tahir, Fatima, Aziz, Tariq, Waseem, Muhammad, Makhdoom, Syeda Izma, Ali, Nouman, Alharbi, Metab, Albekairi, Thamer H., Alasmari, Abdullah F.

“…Heavy metal accumulation increases rapidly in the environment due to anthropogenic activities and industrialization. The leather and surgical industry produces…”
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Blueprint of differentially expressed genes reveals the dynamic gene expression landscape and the gender biases in long COVID by Chakraborty, Chiranjib, Bhattacharya, Manojit, Alshammari, Abdulrahman, Albekairi, Thamer H.

“…Long COVID has appeared as a significant global health issue and is an extra burden to the healthcare system. It affects a considerable number of people…”
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Designing of a multi-epitopes based vaccine against Haemophilius parainfluenzae and its validation through integrated computational approaches by Ghaffar, Sana Abdul, Tahir, Haneen, Muhammad, Sher, Shahid, Muhammad, Naqqash, Tahir, Faisal, Muhammad, Albekairi, Thamer H, Alshammari, Abdulrahman, Albekairi, Norah A, Manzoor, Irfan

“…is a Gram-negative opportunist pathogen within the mucus of the nose and mouth without significant symptoms and has an ability to cause various infections…”
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Development and optimization of film forming non-pressurized liquid bandage for wound healing by Box-Behnken statistical design by Saifullah, Qazi, Sharma, Abhishek, Kabra, Atul, Alshammari, Abdulrahman, Albekairi, Thamer H., Alharbi, Metab, Abdalla, Mohnad

“…The goal of the current investigation was to develop a non-pressurized liquid bandage to promote the healing of wounds by using silver sulfadiazine. A…”
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The Exposure to Lead (Pb) Exacerbates Immunological Abnormalities in BTBR T+ Itpr3tf/J Mice through the Regulation of Signaling Pathways Relevant to T Cells by Assiri, Mohammed A., Albekairi, Thamer H., Ansari, Mushtaq A., Nadeem, Ahmed, Attia, Sabry M., Bakheet, Saleh A., Shahid, Mudassar, Aldossari, Abdullah A., Almutairi, Mohammed M., Almanaa, Taghreed N., Alwetaid, Mohammad Y., Ahmad, Sheikh F.

“…Autism spectrum disorder (ASD) is a common neurodevelopmental illness characterized by abnormal social interactions, communication difficulties, and repetitive…”
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Exploring the structural and molecular interaction landscape of nirmatrelvir and Mpro complex: The study might assist in designing more potent antivirals targeting SARS-CoV-2 and other viruses by Chakraborty, Chiranjib, Bhattacharya, Manojit, Alshammari, Abdulrahman, Alharbi, Metab, Albekairi, Thamer H., Zheng, Chunfu

“…Several therapeutics have been developed and approved against SARS-CoV-2 occasionally; nirmatrelvir is one of them. The drug target of nirmatrelvir is Mpro,…”
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Cadmium Exposure Is Associated with Behavioral Deficits and Neuroimmune Dysfunction in BTBR T + Itpr3tf/J Mice by Alanazi, Mohammed M, Ansari, Mushtaq A, Nadeem, Ahmed, Attia, Sabry M, Bakheet, Saleh A, Al-Mazroua, Haneen A, Aldossari, Abdullah A, Almutairi, Mohammed M, Albekairi, Thamer H, Hussein, Marwa H, Al-Hamamah, Mohammed A, Ahmad, Sheikh F

“…Autism spectrum disorders (ASD) are neurobehavioral disabilities characterized by impaired social interactions, poor communication skills, and…”
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Elucidating the effects of heavy metals contamination on vital organ of fish and migratory birds found at fresh water ecosystem by Khan, Bushra Nisar, ullah, Hamid, Ashfaq, Yusra, Hussain, Nageen, Atique, Usman, Aziz, Tariq, Alharbi, Metab, Albekairi, Thamer H., Alasmari, Abdullah F.

“…Heavy metal pollution in aquatic environments threatens marine life and lowers the quality of freshwater supplies. This research aimed to quantify the heavy…”
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Cardioprotective and hypotensive mechanistic insights of hydroethanolic extract of Cucumis melo L. kernels in isoprenaline-induced cardiotoxicity based on metabolomics and in silico electrophysiological models by Wahid, Muqeet, Saqib, Fatima, Abbas, Ghulam, Shah, Shahid, Alshammari, Abdulrahman, Albekairi, Thamer H, Ali, Anam, Khurm, Muhammad, Mubarak, Mohammad S

“…Cardiovascular diseases (CVD) continue to threaten health worldwide, and account for a significant portion of deaths and illnesses. In both developing and…”
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Histamine H4 Receptor Antagonist Ameliorates the Progression of Experimental Autoimmune Encephalomyelitis via Regulation of T-Cell Imbalance by Aldossari, Abdullah A, Assiri, Mohammed A, Ansari, Mushtaq A, Nadeem, Ahmed, Attia, Sabry M, Bakheet, Saleh A, Albekairi, Thamer H, Alomar, Hatun A, Al-Mazroua, Haneen A, Almanaa, Taghreed N, Al-Hamamah, Mohammed A, Alwetaid, Mohammad Y, Ahmad, Sheikh F

“…Multiple sclerosis (MS) is a degenerative condition characterized by immune-mediated attacks on the central nervous system (CNS), resulting in demyelination…”
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Statistical Analysis and Health Risk Assessment: Vegetables Irrigated with Wastewater in Kirri Shamozai, Pakistan by Khan, Mehak Nawaz, Aslam, Muhammad Anis, Zada, Imran, Albekairi, Thamer H

“…One of the primary environmental routes through which humans are exposed to metals and may be exposed to health risks is the food chain’s contamination with…”
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Designing of a Novel Multi-Antigenic Epitope-Based Vaccine against E. hormaechei : An Intergraded Reverse Vaccinology and Immunoinformatics Approach by Albekairi, Thamer H, Alshammari, Abdulrahman, Alharbi, Metab, Alshammary, Amal F, Tahir Ul Qamar, Muhammad, Ullah, Asad, Irfan, Muhammad, Ahmad, Sajjad

“…is involved in multiple hospital-associated infections and is resistant to beta-lactam and tetracycline antibiotics. Due to emerging antibiotics resistance in…”
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Design of a Multi-Epitope Vaccine against Tropheryma whipplei Using Immunoinformatics and Molecular Dynamics Simulation Techniques by Albekairi, Thamer H, Alshammari, Abdulrahman, Alharbi, Metab, Alshammary, Amal F, Tahir Ul Qamar, Muhammad, Anwar, Tasneem, Ismail, Saba, Shaker, Bilal, Ahmad, Sajjad

“…Whipple's disease is caused by , a Gram-positive pathogenic bacterium. It is considered a persistent infection affecting various organs, more likely to infect…”
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Brain Delivery of a Potent Opioid Receptor Agonist, Biphalin during Ischemic Stroke: Role of Organic Anion Transporting Polypeptide (OATP) by Albekairi, Thamer H, Vaidya, Bhuvaneshwar, Patel, Ronak, Nozohouri, Saeideh, Villalba, Heidi, Zhang, Yong, Lee, Yeon Sun, Al-Ahmad, Abraham, Abbruscato, Thomas J

“…Transporters (expressed) at the blood-brain barrier (BBB) can play an essential role in the treatment of brain injury by transporting neuroprotective substance…”
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Green synthesis and effective genistein production by fungal β-glucosidase immobilized on Al2O3 nanocrystals synthesized in Cajanus cajan L. (Millsp.) leaf extracts by Ali, Sikander, Ejaz, Afra, Rukhma, Usman Ahmad, M., Ullah, Najeeb, Sarwar, Abid, Aziz, Tariq, Albekairi, Thamer H., Alshammari, Abdulrahman

“…The research deals with the isoflavone genistein production, followed by the β-glucosidase production from The leaf extract was prepared and the optimized…”
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Therapeutic benefits of quercetin in traumatic brain injury model exposed to cigarette smoke by Alqahtani, Faleh, Mohamed Ali, Yousif S., Almutairi, Mohammed M., Alotaibi, Abdullah F., Imran, Imran, Alshammari, Musaad A, Alshememry, Abdullah K., AlSharari, Shakir D., Albekairi, Thamer H.

“…Scientific evidences reported the deleterious effect of cigarette smoking or passive smoking on brain health particularly cognitive functions, blood–brain…”
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