Bioactive principles in exudate gel from the leaf of Aloe fleurentiniorum, traditionally used as folkloric medicine by local people of Aridah and Fayfa mountains, Saudi Arabia

Aloe fleurentiniorum is a desert plant that is occasionally used to treat wounds by local people of Aridah and Fayfa mountains in Saudi Arabia. However, medicinal value of the plant has not been scientifically established. The purpose of this study was to determine the bioactive phytocomponents cont...

Full description

Saved in:

Bibliographic Details
Published in:	Arabian journal of chemistry Vol. 14; no. 11; p. 103400
Main Authors:	Sivagurunathan Moni, Sivakumar, Sultan, Muhammad H., Makeen, Hafiz A., Madkhali, Osama A., Ali Bakkari, Mohammed, Alqahtani, Saad S., Alshahrani, Saeed, Joseph Menachery, Santhosh, Intakhab Alam, M., Eltaib Elmobark, Mohamed, ur Rehman, Zia, Shamsher Alam, Md, Yahya Faqihi, Abdulrahman, Mansour Mogaidi, Hassan, Khobrani, Hussein, Albana, Essa, Mutib Sharahily, Ahmed
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 01-11-2021 Elsevier
Subjects:	Aloe fleurentiniorum Anti-bacterial activity Bioactive constituents Desert plant Desert plant Aloe fleurentiniorum Anti-bacterial activity Bioactive constituents
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Aloe fleurentiniorum is a desert plant that is occasionally used to treat wounds by local people of Aridah and Fayfa mountains in Saudi Arabia. However, medicinal value of the plant has not been scientifically established. The purpose of this study was to determine the bioactive phytocomponents contained in the exudate gel (EG) from the leaves of Aloe fleurentiniorum using GC–MS and FT-IR studies, as well as antibacterial assays. Medicinally important bioactive compounds were identified using GC–MS analysis. The bioactive compounds are “pregn-5-ene-3α,20-diol”, “16α-methyl-pregnane-11,20-dione”, “3-hydroxy-(3α,5α)-, ursodeoxycholic acid”, “1-heptatriacotanol”, “allopregnane-7α,11α-diol-3,20-dione”, “D-arabino-hexopyranoside”, “2-octadecenoic acid methyl ester”, “D-ribo-hexose,2,6-dideoxy-3-O-methyl glucosamine”, “N-acetyl-N-benzoyl-alpha-D-glucopyranoside”, “nonyl 1-thio pregnenolone”, “5-cholestene-3-ol, 24-methyl-cholestanol”, and “D-allose hexadecanoic acid methyl ester”. Furthermore, specific groups and their respective chemical compounds were identified via FT-IR spectroscopy studies. The FT-IR spectroscopy of EG showed various functional groups at 3354, 2945, 2832, 2523, 2046, 1707, 1451, 1108, 1031, 880, 737 and 610 cm−1. The FT-IR peaks revealed the likely presence of various compounds such as glycosides, flavonoids, steroids, saponins, flavonoids, amino sugars, cutin and isothiocyanate. Moreover, EG produced a wide range of antibacterial effects on some screened human pathogenic bacteria.
ISSN:	1878-5352 1878-5379
DOI:	10.1016/j.arabjc.2021.103400