Search Results - "Albalawy, Rakan"

Perivascular Adipose Tissue and Perivascular Adipose Tissue-Derived Extracellular Vesicles: New Insights in Vascular Disease by Sigdel, Smara, Udoh, Gideon, Albalawy, Rakan, Wang, Jinju

“…Perivascular adipose tissue (PVAT) is a special deposit of fat tissue surrounding the vasculature. Previous studies suggest that PVAT modulates the vasculature…”
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Protein Synthesis Inhibition Activity of Mesothelin Targeting Immunotoxin LMB-100 Decreases Concentrations of Oncogenic Signaling Molecules and Secreted Growth Factors by El-Behaedi, Salma, Landsman, Rebekah, Rudloff, Michael, Kolyvas, Emily, Albalawy, Rakan, Zhang, Xianyu, Bera, Tapan, Collins, Keith, Kozlov, Serguei, Alewine, Christine

“…LMB-100 is a mesothelin-targeted recombinant immunotoxin (iTox) that carries a modified exotoxin A (PE) payload. PE kills cells by inhibiting synthesis of new…”
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Mesothelin Enhances Tumor Vascularity in Newly Forming Pancreatic Peritoneal Metastases by Avula, Leela Rani, Rudloff, Michael, El-Behaedi, Salma, Arons, Danielle, Albalawy, Rakan, Chen, Xiongfong, Zhang, Xianyu, Alewine, Christine

“…Over 90% of pancreatic ductal adenocarcinomas (PDAC) express mesothelin (MSLN). Overexpression or knockdown of MSLN has been implicated in PDAC aggressiveness…”
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Dysphagia with Blood Disorder? an Unusual Presentation for Paroxysmal Nocturnal Hemoglobinuria by Sheikh, Taha, Albalawy, Rakan, Shuja, Hina, Kahlon, Navkirat M, Hamouda, Danae M

“…Paroxysmal Nocturnal Hemoglobinuria (PNH) is an acquired hemolytic disorder of the multipotent myeloid stem cells, due to underexpression of surface complement…”
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S0333 Utility of Postoperative Circulating Tumor DNA (ctDNA) as a Prognostic Marker of Disease Recurrence in Stage II/III Colon Cancer: A Systematic Review and Meta-Analysis by Alqahtani, Ali, Ghazaleh, Sami, Albalawy, Rakan, Abdulsattar, Waleed, Cook, Michael, Lee-Smith, Wade, Aziz, Muhammad, Alhallak, Mohammed Najeeb

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Abstract 3964: Mesothelin targeting immunotoxin LMB-100 alters the profile of tumor-secreted proteins by El-Behaedi, Salma, Landsman, Rebekah, Rudloff, Michael, Kolyvas, Emily, AlBalawy, Rakan, Alewine, Christine

“…Recombinant immunotoxins are antibody-based therapies that carry a bacterial toxin payload. LMB-100 is a next generation immunotoxin currently being tested in…”
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Abstract 4342: Loss of MSLN impairs pancreatic cancer growth in the peritoneal cavity by Rudloff, Michael W., Arons, Danielle, El-Behaedi, Salma, Albalawy, Rakan, Alewine, Christine

“…Mesothelin (MSLN) is a cell surface glycoprotein that is expressed in at least 85% of pancreatic adenocarcinoma but not on cells of the healthy pancreas nor in…”
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