Search Results - "Albadrani, Ghadeer M."
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Mechanistic insights and perspectives involved in neuroprotective action of quercetin
Published in Biomedicine & pharmacotherapy (01-08-2021)“…Neurodegenerative diseases (NDDs) are the primary cause of disabilities in the elderly people. Growing evidence indicates that oxidative stress, mitochondrial…”
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Potential Role of Curcumin and Its Nanoformulations to Treat Various Types of Cancers
Published in Biomolecules (Basel, Switzerland) (07-03-2021)“…Cancer is a major burden of disease globally. Each year, tens of millions of people are diagnosed with cancer worldwide, and more than half of the patients…”
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Ameliorating effect of probiotic on nonalcoholic fatty liver disease and lipolytic gene expression in rabbits
Published in Scientific reports (18-04-2023)“…Nonalcoholic fatty liver disease (NAFLD) is a condition that affects about 24% of people worldwide. Increased liver fat, inflammation, and, in the most severe…”
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Mesoporous Carbon: A Versatile Material for Scientific Applications
Published in International journal of molecular sciences (26-04-2021)“…Mesoporous carbon is a promising material having multiple applications. It can act as a catalytic support and can be used in energy storage devices. Moreover,…”
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Molecular Mechanisms of Astaxanthin as a Potential Neurotherapeutic Agent
Published in Marine drugs (03-04-2021)“…Neurological disorders are diseases of the central and peripheral nervous system that affect millions of people, and the numbers are rising gradually. In the…”
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Multiple strategies with the synergistic approach for addressing colorectal cancer
Published in Biomedicine & pharmacotherapy (01-08-2021)“…Cancer treatment is improving widely over time, but finding a proper defender to beat them seems like a distant dream. The quest for identification and…”
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Animal models of diabetic microvascular complications: Relevance to clinical features
Published in Biomedicine & pharmacotherapy (01-01-2022)“…Diabetes has become more common in recent years worldwide, and this growth is projected to continue in the future. The primary concern with diabetes is…”
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5-Fluorouracil-Loaded Folic-Acid-Fabricated Chitosan Nanoparticles for Site-Targeted Drug Delivery Cargo
Published in Polymers (13-05-2022)“…Nanoparticles play a vital role in cancer treatment to deliver or direct the drug to the malignant cell, avoiding the attacking of normal cells. The aim of the…”
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Anti-Alzheimer's Molecules Derived from Marine Life: Understanding Molecular Mechanisms and Therapeutic Potential
Published in Marine drugs (28-04-2021)“…Alzheimer's disease (AD) is a devastating neurodegenerative disease and the most common cause of dementia. It has been confirmed that the pathological…”
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Mechanistic correlation between mitochondrial permeability transition pores and mitochondrial ATP dependent potassium channels in ischemia reperfusion
Published in Biomedicine & pharmacotherapy (01-06-2023)“…Mitochondrial dysfunction is one of the fundamental causes of ischemia reperfusion (I/R) damage. I/R refers to the paradoxical progression of cellular…”
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Exploration of therapeutic applicability and different signaling mechanism of various phytopharmacological agents for treatment of breast cancer
Published in Biomedicine & pharmacotherapy (01-07-2021)“…Cancer is one of the most dreaded diseases characterized by uncontrolled proliferation of abnormal cells that occurs due to impairment of cell division and…”
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Mitigative potential of kaempferide against polyethylene microplastics induced testicular damage by activating Nrf-2/Keap-1 pathway
Published in Ecotoxicology and environmental safety (01-01-2024)“…Polyethylene microplastics (PE-MPs) are one of the environmental contaminants that instigate oxidative stress (OS) in various organs of the body, including…”
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Albendazole repurposing on VEGFR-2 for possible anticancer application: In-silico analysis
Published in PloS one (16-08-2023)“…Drug repurposing is the finding new activity of the existing drug. Recently, Albendazole’s well-known antihelmintic has got the attention of an anticancer…”
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Natural bioactive molecules: An alternative approach to the treatment and control of glioblastoma multiforme
Published in Biomedicine & pharmacotherapy (01-09-2021)“…Glioblastoma multiforme is one of the most deadly malignant tumors, with more than 10,000 cases recorded annually in the United States. Various clinical…”
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The anticoccidial effects of probiotics and prebiotics on the live coccidia vaccine and the subsequent influence on poultry performance post-challenge with mixed Eimeria species
Published in Poultry science (01-12-2024)“…Live vaccines containing Eimeria oocysts are commercially available to protect against avian coccidiosis. Additionally, probiotics (PRO) and prebiotics (PRE)…”
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Eriodictyol attenuates Furan induced testicular toxicity in Rats: Role of oxidative stress, steroidogenic enzymes and apoptosis
Published in Ecotoxicology and environmental safety (01-07-2023)“…Furan (C4H4O) is a naturally occurring organic compound. It develops as a result of the thermal processing of food and stimulates critical impairments in male…”
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Neuroinflammatory Signaling in the Pathogenesis of Alzheimers Disease
Published in Current neuropharmacology (01-01-2022)“…Alzheimers disease (AD) is a chronic neurodegenerative disease characterized by theformation of intracellular neurofibrillary tangles (NFTs) and extracellular…”
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A Comprehensive Approach to Derivatization: Elemental Composition, Biochemical, and In Silico Studies of Metformin Derivatives Containing Copper and Zinc Complexes
Published in Molecules (Basel, Switzerland) (01-02-2023)“…The current study was designed to synthesize, characterize, and screen the molecular and biological activities of different metformin derivatives that possess…”
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Unveiling the antimicrobial and antibiofilm potential of biosurfactant produced by newly isolated Lactiplantibacillus plantarum strain 1625
Published in Frontiers in microbiology (10-09-2024)“…The present study aimed to characterize the biosurfactants synthesized by lactic acid bacteria (LAB) obtained from fermented foods, optimize the conditions for…”
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Recognizing novel drugs against Keap1 in Alzheimer's disease using machine learning grounded computational studies
Published in Frontiers in molecular neuroscience (06-12-2022)“…Alzheimer's disease (AD) is the most common neurodegenerative disorder in the world, affecting an estimated 50 million individuals. The nerve cells become…”
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