Search Results - "Alawi, Khadija"

Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation by Romeo, Sara G., Alawi, Khadija M., Rodrigues, Julia, Singh, Amit, Kusumbe, Anjali P., Ramasamy, Saravana K.

“…Growth plate cartilage contributes to the generation of a large variety of shapes and sizes of skeletal elements in the mammalian system. The removal of…”
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The paradoxical role of the transient receptor potential vanilloid 1 receptor in inflammation by Alawi, Khadija, Keeble, Julie

“…The transient potential receptor vanilloid 1 (TRPV1) receptor is a non-selective cation channel that is chemically activated by capsaicin, the pungent…”
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TRPA1 is essential for the vascular response to environmental cold exposure by Aubdool, Aisah A., Graepel, Rabea, Kodji, Xenia, Alawi, Khadija M., Bodkin, Jennifer V., Srivastava, Salil, Gentry, Clive, Heads, Richard, Grant, Andrew D., Fernandes, Elizabeth S., Bevan, Stuart, Brain, Susan D.

“…The cold-induced vascular response, consisting of vasoconstriction followed by vasodilatation, is critical for protecting the cutaneous tissues against cold…”
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Tail-Cuff Technique and Its Influence on Central Blood Pressure in the Mouse by Wilde, Elena, Aubdool, Aisah A, Thakore, Pratish, Baldissera, Jr, Lineu, Alawi, Khadija M, Keeble, Julie, Nandi, Manasi, Brain, Susan D

“…Reliable measurement of blood pressure in conscious mice is essential in cardiovascular research. Telemetry, the "gold-standard" technique, is invasive and…”
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Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation by Alawi, Khadija M, Russell, Fiona A, Aubdool, Aisah A, Srivastava, Salil, Riffo-Vasquez, Yanira, Baldissera, Jr, Lineu, Thakore, Pratish, Saleque, Nurjahan, Fernandes, Elizabeth S, Walsh, David A, Brain, Susan D

“…Transient receptor potential canonical 5 (TRPC5) is functionally expressed on a range of cells including fibroblast-like synoviocytes, which play an important…”
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A Novel α-Calcitonin Gene-Related Peptide Analogue Protects Against End-Organ Damage in Experimental Hypertension, Cardiac Hypertrophy, and Heart Failure by Aubdool, Aisah A, Thakore, Pratish, Argunhan, Fulye, Smillie, Sarah-Jane, Schnelle, Moritz, Srivastava, Salil, Alawi, Khadija M, Wilde, Elena, Mitchell, Jennifer, Farrell-Dillon, Keith, Richards, Daniel A, Maltese, Giuseppe, Siow, Richard C, Nandi, Manasi, Clark, James E, Shah, Ajay M, Sams, Anette, Brain, Susan D

“…BACKGROUND:Research into the therapeutic potential of α-calcitonin gene–related peptide (α-CGRP) has been limited because of its peptide nature and short…”
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The sympathetic nervous system is controlled by transient receptor potential vanilloid 1 in the regulation of body temperature by Alawi, Khadija M., Aubdool, Aisah A., Liang, Lihuan, Wilde, Elena, Vepa, Abhinav, Psefteli, Maria‐Paraskevi, Brain, Susan D., Keeble, Julie E.

“…ABSTRACT Transient receptor potential vanilloid 1 (TRPV1) is involved in sensory nerve nociceptive signaling. Recently, it has been discovered that TRPV1…”
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(-)-Englerin-A Has Analgesic and Anti-Inflammatory Effects Independent of TRPC4 and 5 by de Sousa Valente, João, Alawi, Khadija M, Bharde, Sabah, Zarban, Ali A, Kodji, Xenia, Thapa, Dibesh, Argunhan, Fulye, Barrett, Brentton, Nagy, Istvan, Brain, Susan D

“…Recently, we found that the deletion of TRPC5 leads to increased inflammation and pain-related behaviour in two animal models of arthritis. (-)-Englerin A…”
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Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner by Fernandes, Elizabeth S, Russell, Fiona A, Alawi, Khadija M, Sand, Claire, Liang, Lihuan, Salamon, Robin, Bodkin, Jennifer V, Aubdool, Aisah A, Arno, Matthew, Gentry, Clive, Smillie, Sarah-Jane, Bevan, Stuart, Keeble, Julie E, Malcangio, Marzia, Brain, Susan D

“…The effect of cold temperature on arthritis symptoms is unclear. The aim of this study was to investigate how environmental cold affects pain and blood flow in…”
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Transient receptor potential canonical 5 channels plays an essential role in hepatic dyslipidemia associated with cholestasis by Alawi, Khadija M., Tandio, David, Xu, Jin, Thakore, Pratish, Papacleovoulou, Georgia, Fernandes, Elizabeth S., Legido-Quigley, Cristina, Williamson, Catherine, Brain, Susan D.

“…Transient receptor potential canonical 5 (TRPC5), a calcium-permeable, non-selective cation channel is expressed in the periphery, but there is limited…”
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Examining the role of transient receptor potential canonical 5 (TRPC5) in osteoarthritis by de Sousa Valente, João, Alawi, Khadija M., Keringer, Patrik, Bharde, Sabah, Ayaz, Faseeha, Saleque, Nurjahan, Kodji, Xenia, Thapa, Dibesh, Argunhan, Fulye, Brain, Susan D.

“…Osteo-arthritis (OA) involves joint degradation and usually pain; with mechanisms poorly understood and few treatment options. There is evidence that the…”
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Control of the sympathetic nervous system by TRPV1 in the regulation of body temperature by Alawi, Khadija, Aubdool, Aisah, Liang, Lihuan, Wilde, Elena, Vepa, Abhinav, Psefteli, Paraskevi-Maria, Brain, Susan, Keeble, Julie

“…Transient receptor potential vanilloid 1 (TRPV1) is involved in pain and neurogenic inflammation. It has recently been found that TRPV1 anatgonism causes…”
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Transient Receptor Potential Canonical Channels 4 and 5 Mediate Escherichia coli-Derived Thioredoxin Effects in Lipopolysaccharide-Injected Mice by P. Pereira, Ione C., Nascimento da Silva, Luís Cláudio, Monteiro-Neto, Valério, Costa, Soraia K. P., da Costa, Robson, Calixto, João Batista, Brain, Susan D., Fernandes, Elizabeth S., Castro, José A., da Silva, João F. R., Sousa, Nágila Caroline Fialho, Aubdool, Aisah, Thakore, Pratish, Alawi, Khadija, Mendes, Saulo J. F., Pereira, Domingos Magno Santos, Grisotto, Marcos A. G.

“…Thioredoxin plays an essential role in bacterial antioxidant machinery and virulence; however, its regulatory actions in the host are less well understood…”
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