Search Results - "Alase, A."

Non-invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases-A Focus on Psoriasis and Lupus erythematosus by Berekméri, Anna, Tiganescu, Ana, Alase, Adewonuola A, Vital, Edward, Stacey, Martin, Wittmann, Miriam

“…The traditional diagnostic gold standard for inflammatory skin lesions of unclear etiology is dermato-histopathology. As this approach requires an invasive…”
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Interleukin-33 modulates the expression of human β-defensin 2 in human primary keratinocytes and may influence the susceptibility to bacterial superinfection in acute atopic dermatitis by Alase, A., Seltmann, J., Werfel, T., Wittmann, M.

“…Summary Background  Interleukin (IL)‐33 is a member of the IL‐1 family and has been implicated in Th2‐driven allergic diseases such as atopic dermatitis (AD)…”
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Antimicrobial Peptide LL-37 Facilitates Intracellular Uptake of RNA Aptamer Apt 21-2 Without Inducing an Inflammatory or Interferon Response by Macleod, Tom, Ward, Joseph, Alase, Adewonuola A, Bridgewood, Charlie, Wittmann, Miriam, Stonehouse, Nicola J

“…RNA aptamers are synthetic single stranded RNA oligonucleotides that function analogously to antibodies. Recently, they have shown promise for use in treating…”
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PO.3.64 Optimising type I interferon gene expression assays: addressing the research agenda of a eular task force by Wigston, Z, Carter, L, Alase, A, Vital, E

“…PurposeType I interferon (IFN-I) assays are an important emerging biomarker in SLE. A EULAR Task Force for IFN-I assays proposed a research agenda, which…”
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Interleukin-22 drives the proliferation, migration and osteogenic differentiation of mesenchymal stem cells: a novel cytokine that could contribute to new bone formation in spondyloarthropathies by El-Zayadi, Ahmed A, Jones, Elena A, Churchman, Sarah M, Baboolal, Thomas G, Cuthbert, Richard J, El-Jawhari, Jehan J, Badawy, Ahmed M, Alase, Adewonuola A, El-Sherbiny, Yasser M, McGonagle, Dennis

“…The SpAs are genetically and therapeutically linked to IL-23, which in turn regulates IL-22, a cytokine that has been implicated in the regulation of new bone…”
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IFNλ Stimulates MxA Production in Human Dermal Fibroblasts via a MAPK-Dependent STAT1-Independent Mechanism by Alase, Adewonuola A., El-Sherbiny, Yasser M., Vital, Edward M., Tobin, Desmond J., Turner, Neil A., Wittmann, Miriam

“…IFNλ is important for epidermal defense against viruses. It is produced by, and acts on, keratinocytes, whereas fibroblasts were previously considered to be…”
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IFN[lambda] Stimulates MxA Production in Human Dermal Fibroblasts via a MAPK-Dependent STAT1-Independent Mechanism by Alase, Adewonuola A, El-sherbiny, Yasser M, Vital, Edward M, Tobin, Desmond J, Turner, Neil A, Wittmann, Miriam

“…IFNλ is important for epidermal defense against viruses. It is produced by, and acts on, keratinocytes, whereas fibroblasts were previously considered to be…”
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Plucked hair follicles from patients with chronic discoid lupus erythematosus show a disease-specific molecular signature by Shalbaf, Mohammad, Alase, Adewonuola A, Berekmeri, Anna, Md Yusof, Md Yuzaiful, Pistolic, Jelena, Goodfield, Mark J, Edward, Sara, Botchkareva, Natalia V, Stacey, Martin, Vital, Edward M, Wittmann, Miriam

“…ObjectiveWhen faced with clinical symptoms of scarring alopecia—the standard diagnostic pathway involves a scalp biopsy which is an invasive and expensive…”
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428 Comparative mass spectrometry proteomics of epidermal samples obtained by non-invasive tape stripping from inflammatory skin diseases by Berekméri, A., Alase, A., Macleod, T., Shaheed, S., Sutton, C., Stacey, M., Wittmann, M.

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411 The production and responsiveness to skin interferon (IFNλ1) are regulated by TNF-α by Alase, A., Stacey, M., Goodfield, M., Wittmann, M.

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323 IL-36y stimulation induces proinflammatory effects on human endothelial cells by Bridgewood, C., Stacey, M., Alase, A., Graham, A., Lagos, D., Wittmann, M.

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385 Cathepsin S is up-regulated in psoriatic inflammation and activates the pro-inflammatory cytokine IL-36γ by Ainscough, J.S., Macleod, T., Alase, A., Latzko, A., Whittmann, M., Stacey, M.

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