Search Results - "Alani, Sara"

Deubiquitinase OTUD6B Isoforms Are Important Regulators of Growth and Proliferation by Sobol, Anna, Askonas, Caroline, Alani, Sara, Weber, Megan J, Ananthanarayanan, Vijayalakshmi, Osipo, Clodia, Bocchetta, Maurizio

“…Deubiquitinases (DUB) are increasingly linked to the regulation of fundamental processes in normal and cancer cells, including DNA replication and repair,…”
Get full text

Depletion of Amyloid Precursor Protein (APP) Causes G0 Arrest in Non-Small Cell Lung Cancer (NSCLC) Cells by Sobol, Anna, Galluzzo, Paola, Weber, Megan J., Alani, Sara, Bocchetta, Maurizio

“…We recently reported that Amyloid Precursor Protein (APP) regulates global protein synthesis in a variety of human dividing cells, including non‐small cell…”
Get full text

Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222 by Singh, Ashvani K, Fan, Yihong, Balut, Corina, Alani, Sara, Manelli, Arlene M, Swensen, Andrew M, Jia, Ying, Neelands, Torben R, Vortherms, Timothy A, Liu, Bo, Searle, Xenia B, Wang, Xueqing, Gao, Wenqing, Hwang, Tzyh-Chang, Ren, Hong Y, Cyr, Douglas, Kym, Philip R, Conrath, Katja, Tse, Chris

“…Cystic fibrosis (CF) is the most common monogenic autosomal recessive disease in Caucasians caused by pathogenic mutations in the cystic fibrosis transmembrane…”
Get full text

Amyloid Precursor Protein (APP) Affects Global Protein Synthesis in Dividing Human Cells by Sobol, Anna, Galluzzo, Paola, Liang, Shuang, Rambo, Brittany, Skucha, Sylvia, Weber, Megan J., Alani, Sara, Bocchetta, Maurizio

“…Hypoxic non‐small cell lung cancer (NSCLC) is dependent on Notch‐1 signaling for survival. Targeting Notch‐1 by means of γ‐secretase inhibitors (GSI) proved…”
Get full text