Search Results - "Alangari, Abdullah"
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Corticosteroids in the treatment of acute asthma
Published in Annals of thoracic medicine (01-10-2014)“…Asthma is a prevalent chronic disease of the respiratory system and acute asthma exacerbations are among the most common causes of presentation to the…”
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2
First report of anaphylaxis to miswak (Salvadora persica)
Published in Pediatric allergy and immunology (01-10-2024)Get full text
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Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like disorder caused by loss-of-function mutations in LRBA
Published in Journal of allergy and clinical immunology (01-01-2015)“…Background A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They…”
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The Saudi Initiative for Asthma - 2021 Update: Guidelines for the diagnosis and management of asthma in adults and children
Published in Annals of thoracic medicine (01-01-2021)“…The Saudi Initiative for Asthma 2021 (SINA-2021) is the fifth version of asthma guidelines for the diagnosis and management of asthma for adults and children,…”
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5
JAK Inhibitor Therapy in a Child with Inherited USP18 Deficiency
Published in The New England journal of medicine (16-01-2020)“…A neonate with a loss-of-function mutation in USP18 and exuberant expression of interferon-stimulated genes was experimentally treated with ruxolitinib, which…”
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6
Manuka honey activates the aryl hydrocarbon receptor: Implications for skin inflammation
Published in Pharmacological research (01-08-2023)“…Manuka honey (MH) is a complex nutritional material with antimicrobial, antioxidant and anti-inflammatory activity. We have previously shown that MH down…”
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The Saudi Initiative for Asthma - 2019 Update: Guidelines for the diagnosis and management of asthma in adults and children
Published in Annals of thoracic medicine (01-01-2019)“…This is the fourth version of the updated guidelines for the diagnosis and management of asthma, developed by the Saudi Initiative for Asthma (SINA) group, a…”
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8
Immune dysregulation caused by homozygous mutations in CBLB
Published in The Journal of clinical investigation (15-10-2022)“…CBL-B is an E3 ubiquitin ligase that ubiquitinates proteins downstream of immune receptors to downregulate positive signaling cascades. Distinct homozygous…”
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9
Genomic and non-genomic actions of glucocorticoids in asthma
Published in Annals of thoracic medicine (01-07-2010)“…Glucocorticoids are the mainstay of asthma therapy. They are primarily used to suppress airway inflammation, which is the central pathological change in…”
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10
LPS-responsive beige-like anchor ( LRBA ) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency
Published in Journal of allergy and clinical immunology (01-08-2012)“…Background Clinical immunology has traditionally relied on accurate phenotyping of the patient's immune dysfunction for the identification of a candidate gene…”
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Accelerating matchmaking of novel dysmorphology syndromes through clinical and genomic characterization of a large cohort
Published in Genetics in medicine (01-07-2016)“…Dysmorphology syndromes are among the most common referrals to clinical genetics specialists. Inability to match the dysmorphology pattern to a known syndrome…”
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12
Case report: Durable response to ruxolitinib in a child with TREX1 -related disorder
Published in Frontiers in pediatrics (28-04-2023)“…JAK inhibitors are useful in treating interferonopathies, presumably because they downregulate the JAK/STAT signaling. There are limited studies about the…”
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13
Responsiveness of sphingosine phosphate lyase insufficiency syndrome to vitamin B6 cofactor supplementation
Published in Journal of inherited metabolic disease (01-09-2020)“…Sphingosine‐1‐phosphate (S1P) lyase is a vitamin B6‐dependent enzyme that degrades sphingosine‐1‐phosphate in the final step of sphingolipid metabolism. In…”
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14
Budesonide nebulization added to systemic prednisolone in the treatment of acute asthma in children: a double-blind, randomized, controlled trial
Published in Chest (01-04-2014)“…Inhaled corticosteroids, known to be effective as a maintenance medication in chronic asthma, have also been suggested as a therapy for acute asthma when given…”
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Admission predictability of children with acute asthma
Published in Annals of thoracic medicine (01-01-2018)“…OBJECTIVES: We aimed to evaluate the seasonal variations of acute asthma presentation in children and the utility of the pediatric asthma score (PAS) and its…”
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A Novel Homozygous Mutation in G6PC3 Presenting as Cyclic Neutropenia and Severe Congenital Neutropenia in the Same Family
Published in Journal of clinical immunology (01-11-2013)“…Purpose Patients with autosomal recessive cyclic neutropenia have no known causative genetic defect yet. Methods Autozygosity mapping on two branches of an…”
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17
Honey is potentially effective in the treatment of atopic dermatitis: Clinical and mechanistic studies
Published in Immunity, Inflammation and Disease (01-06-2017)“…Introduction As manuka honey (MH) exhibits immunoregulatory and anti‐staphylococcal activities, we aimed to investigate if it could be effective in the…”
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Obesity and Kidney Transplant Candidates: An Outcome Analysis Based on Body Mass Index
Published in Curēus (Palo Alto, CA) (05-02-2023)“…Background Obesity is a well-established risk factor for a decline in renal function and post-operative complications. Also, obese patients suffer worse…”
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The effect of sand storms on acute asthma in Riyadh, Saudi Arabia
Published in Annals of thoracic medicine (01-01-2015)“…Major sand storms are frequent in the Middle East. This study aims to investigate the role of air particulate matter (PM) level in acute asthma in children in…”
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Colonic basidiobolomycosis presenting with intestinal obstruction and a normal eosinophil count
Published in IDCases (01-01-2019)“…Gastrointestinal basidiobolomycosis (GIB), caused by Basidiobolus ranrum, is a rare fungal infection with a limited geographic distribution. The majority of…”
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