Search Results - "Alanazi, Fares K."
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Design and synthesis of new cholesterol-conjugated 5-Fluorouracil: a novel potential delivery system for cancer treatment
Published in Molecules (Basel, Switzerland) (26-08-2014)“…Cholesterol-conjugated 5-fluorouracil prodrugs were designed to be carried in vivo via low density lipoproteins (LDL) and subsequently undergo…”
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Novel Ethyl 1,5-Disubstituted-1H-Pyrazole-3-Carboxylates as a New Class of Antimicrobial Agents
Published in Acta Pharmaceutica (01-09-2014)“…A series of pyrazole derivatives 9-22 were designed and synthesized. All the newly synthesized compounds were assayed for their antimicrobial activity against…”
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Targeting cancer using cholesterol conjugates
Published in Saudi pharmaceutical journal (01-01-2014)“…Conjugation of cholesterol moiety to active compounds for either cancer treatment or diagnosis is an attractive approach. Cholesterol derivatives are widely…”
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Target β-catenin/CD44/Nanog axis in colon cancer cells by certain N′-(2-oxoindolin-3-ylidene)-2-(benzyloxy)benzohydrazides
Published in Bioorganic & medicinal chemistry letters (01-04-2016)“…[Display omitted] Cell surface molecule CD44 plays a major role in regulation of cancer stem cells CSCs on both phenotypic and functional level, however…”
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