Search Results - "Alanazi, E."
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EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation: In Vivo and in Vitro Rat Studies
Published in Chemical research in toxicology (20-07-2020)“…Gefitinib (GEF) is a selective inhibitor of the epidermal growth factor receptor (EGFR) used to treat non-small cell lung cancer. Yet, few cases of…”
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Double layer lanthanide -Pt/TiO2 nanotube arrays electrode as a cost-highly efficient electrocatalyst for hydrogen evolution in acid media
Published in Journal of experimental nanoscience (01-12-2021)“…Self-organized anodic double layer TiO 2 nanotube arrays (TNTAs) were sensitized by an electrochemical anodization process on a Ti sheet with a two-step…”
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Optimization of Bromocriptine-Mesylate-Loaded Polycaprolactone Nanoparticles Coated with Chitosan for Nose-to-Brain Delivery: In Vitro and In Vivo Studies
Published in Polymers (26-09-2023)“…Bromocriptine mesylate (BM), primarily ergocryptine, is a dopamine agonist derived from ergot alkaloids. This study aimed to formulate chitosan (CS)-coated…”
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Synthesis, anticancer, apoptosis-inducing activities and EGFR and VEGFR2 assay mechanistic studies of 5,5-diphenylimidazolidine-2,4-dione derivatives: Molecular docking studies
Published in Saudi pharmaceutical journal (01-07-2019)“…A new series of 5,5-diphenylhydantoin derivatives containing benzylidene or isatin (4–19) was synthesized. Their anticancer activity against HeLa, a cervical…”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published in Saudi pharmaceutical journal (01-02-2022)“…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of…”
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Exploring the Oral Manifestations and Hazards to Dental Professionals During the COVID-19 Pandemic: A Scoping Review
Published in Journal of pharmacy & bioallied science (01-02-2024)“…The novel coronavirus (COVID-19) has inundated the whole world by causing severe acute respiratory syndrome in humans, thus posing serious public health…”
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Mesenchymal stem cell therapy in diabetic foot ulcer: An updated comprehensive review
Published in Health science reports (01-04-2024)“…Background Diabetes has evolved into a worldwide public health issue. One of the most serious complications of diabetes is diabetic foot ulcer (DFU), which…”
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Rhabdomyosarcoma in children: Retrospective analysis from a single tertiary care center in Saudi Arabia
Published in Cancer reports (01-01-2023)“…Background Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children occurring most commonly in the head and neck region. The treatment…”
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Gold-containing compound BDG-I inhibits the growth of A549 lung cancer cells through the deregulation of miRNA expression
Published in Saudi pharmaceutical journal (01-11-2018)“…Gold complex bis(diethyldithiocarbamato-gold(I)) bis(diphenylphosphino) methane (BDG-I) is cytotoxic toward different cancer cell lines. We compared the…”
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Novel hydrazine sensors based on Pd electrodeposited on highly dispersed lanthanide-doped TiO2 nanotubes
Published in Journal of electroanalytical chemistry (Lausanne, Switzerland) (01-01-2020)“…Electrodes made by electrodepositing Pd on lanthanide (Nd, Gd, Nd/Gd)-doped titania nanotubes (TNTs; prepared using a hydrothermal method) on Au substrates…”
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The Interplay of Carveol and All-Trans Retinoic Acid (ATRA) in Experimental Parkinson’s Disease: Role of Inflammasome-Mediated Pyroptosis and Nrf2
Published in Neurochemical research (01-11-2024)“…Parkinson’s disease (PD) is a debilitating and the second most common neurodegenerative disorder with a high prevalence. PD has a multifaceted etiology…”
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Lead Nitrate Induces Inflammation and Apoptosis in Rat Lungs Through the Activation of NF-κB and AhR Signaling Pathways
Published in Environmental science and pollution research international (01-09-2022)“…Lead (Pb) is one of the most frequent hazardous air contaminants, where the lungs are particularly vulnerable to its toxicity. However, the Pb distribution and…”
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Evolutionary analysis of LMP-1 genetic diversity in EBV-associated nasopharyngeal carcinoma: Bioinformatic insights into oncogenic potential
Published in Infection, genetics and evolution (01-06-2024)“…EBV latent membrane protein 1 (LMP-1) is an important oncogene involved in the induction and maintenance of EBV infection and the activation of several cell…”
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
Published in Toxicology mechanisms and methods (12-02-2019)“…Although a plethora of studies have examined tobacco smoke-cancer disease association, the involvement of cellular genetic toxicity remains unclear. Therefore,…”
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In vivo and in vitro studies evaluating the chemopreventive effect of metformin on the aryl hydrocarbon receptor-mediated breast carcinogenesis
Published in Saudi journal of biological sciences (01-12-2021)“…Metformin (MET) is a clinically used anti-hyperglycemic agent that shows activities against chemically-induced animal models of cancer. A study from our…”
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Long-term Immunity Against Hepatitis B Virus After Routine Immunization Among Adults Visiting Primary Care Centers in Riyadh, Saudi Arabia
Published in Curēus (Palo Alto, CA) (15-01-2022)“…Objective This study aimed to determine the persistence of induced immunity against hepatitis B virus (HBV) among adults routinely vaccinated during their…”
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Knowledge and Barriers About Blood Donation and Associated Factors in Saudi Arabia: A Systematic Review
Published in Curēus (Palo Alto, CA) (01-11-2023)“…Transfusions and blood donations are relatively risk-free medical procedures. However, attitudes, beliefs, and knowledge levels about blood donation and…”
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Nd-Gd–Platinum doped TiO2 nanotube arrays catalyst for water splitting in Alkaline Medium
Published in International journal of electrochemical science (01-06-2023)“…The utilization of a highly efficient electrocatalyst for the hydrogen evolution reaction (HER) plays an important role in energy conversion in regard to the…”
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