Search Results - "Alamoudi, Jawaher Abdullah"
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Nonsteroidal anti-inflammatory drug solubility optimization through green chemistry solvent: Artificial intelligence technique
Published in Case studies in thermal engineering (01-01-2024)“…This research paper presents a comprehensive thermodynamic and heat transfer study on predicting the ternary solubility of Nystatin in SC-CO2-Ethanol…”
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Preparation and evaluation of transdermal hydrogel of chitosan coated nanocurcumin for enhanced stability and skin permeability
Published in Arabian journal of chemistry (01-12-2023)“…Curcumin (CR) is a natural product that has great interest in biopharmaceutical applications. It has several biological effects that antagonizes inflammation,…”
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Recent advancements toward the incremsent of drug solubility using environmentally-friendly supercritical CO2: a machine learning perspective
Published in Frontiers in medicine (02-09-2024)“…Inadequate bioavailability of therapeutic drugs, which is often the consequence of their unacceptable solubility and dissolution rates, is an indisputable…”
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Species differences in bile acids I. Plasma and urine bile acid composition
Published in Journal of applied toxicology (01-10-2018)“…Maintenance of bile acid (BA) homeostasis is essential to achieve their physiologic functions and avoid their toxic effects. The marked differences in BA…”
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Species differences in bile acids II. Bile acid metabolism
Published in Journal of applied toxicology (01-10-2018)“…One of the mechanisms of drug‐induced liver injury (DILI) involves alterations in bile acid (BA) homeostasis and elimination, which encompass several metabolic…”
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Analysis of nanomedicine production via green processing: Modeling and simulation of pharmaceutical solubility using artificial intelligence
Published in Case studies in thermal engineering (01-11-2023)“…This research focuses on investigating the solubility of tolfenamic acid in SC-CO2 (supercritical carbon dioxide) and the density of SC-CO2 solvent via…”
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Data-driven models and comparison for correlation of pharmaceutical solubility in supercritical solvent based on pressure and temperature as inputs
Published in Case studies in thermal engineering (01-09-2023)“…Data-driven models were employed for the solubility correlation, while the focus was on modeling the solubility of raloxifene drug and density of carbon…”
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Theoretical investigations on modeling blood flow through vessel for understanding effectiveness of magnetic nanocarrier drug delivery systems
Published in Frontiers in medicine (22-05-2024)“…For cancer therapy, the focus is now on targeting the chemotherapy drugs to cancer cells without damaging other normal cells. The new materials based on…”
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Application of CO2 Supercritical Fluid to Optimize the Solubility of Oxaprozin: Development of Novel Machine Learning Predictive Models
Published in Molecules (Basel, Switzerland) (06-09-2022)“…Over the last years, extensive motivation has emerged towards the application of supercritical carbon dioxide (SCCO2) for particle engineering. SCCO2 has great…”
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Fabrication, assessment, and optimization of alendronate sodium nanoemulsion-based injectable in-situ gel formulation for management of osteoporosis
Published in Drug delivery (01-12-2023)“…Low bone mass, degeneration of bone tissue, and disruption of bone microarchitecture are all symptoms of the disease osteoporosis, which can decrease bone…”
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Anticancer potentials of metformin loaded coconut oil nanoemulsion on MCF-7, HepG2 and HCT-116 cell lines
Published in Artificial cells, nanomedicine, and biotechnology (01-12-2023)“…In order to load metformin in a nano formula and evaluate the produced nano form towards cancer cells, metformin was loaded on natural carrier coconut oil. The…”
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Chitosan/hesperidin nanoparticles formulation: a promising approach against ethanol-induced gastric ulcers via Sirt1/FOXO1/PGC-1α/HO-1 pathway
Published in Frontiers in pharmacology (09-09-2024)“…Hesperidin (Hes) protects different organs from damage by acting as a potent antioxidant and anti-inflammatory. This study aims to evaluate the…”
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Structural, mechanical, barrier and antioxidant properties of pectin and xanthan gum edible films loaded with grapefruit essential oil
Published in Heliyon (15-02-2024)“…This research focused on the development of films based on pectin and xanthan gum composite loaded with different concentrations of grapefruit essential oil…”
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Fabrication of Nanocrystals for Enhanced Distribution of a Fatty Acid Synthase Inhibitor (Orlistat) as a Promising Method to Relieve Solid Ehrlich Carcinoma-Induced Hepatic Damage in Mice
Published in Pharmaceuticals (Basel, Switzerland) (01-01-2024)“…Orlistat (ORL) is an effective irreversible inhibitor of the lipase enzyme, and it possesses anticancer effects and limited aqueous solubility. This study was…”
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Appropriateness of anticoagulation level in older adult patients on Warfarin: A multicenter retrospective study
Published in Saudi pharmaceutical journal (01-01-2024)“…Warfarin is favored over newer direct oral anticoagulants (DOACs) for many older adults. However, its use necessitates rigorous monitoring due to the fine line…”
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Urinary BA Indices as Prognostic Biomarkers for Complications Associated with Liver Diseases
Published in International journal of hepatology (New York) (30-03-2022)“…Hepatobiliary diseases and their complications cause the accumulation of toxic bile acids (BA) in the liver, blood, and other tissues, which may exacerbate the…”
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Fabrication and Evaluation of W/O Emulsion Loaded with Linum usitatissimum Seeds Extract for Anti-Leishmaniasis Efficacy
Published in Antibiotics (Basel) (23-03-2022)“…Leishmaniasis, remains a serious health problem in many developing countries with thousands of new cases recorded annually. Novel therapies are required as…”
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Recent advancements toward the incremsent of drug solubility using environmentally-friendly supercritical CO 2 : a machine learning perspective
Published in Frontiers in medicine (2024)“…Inadequate bioavailability of therapeutic drugs, which is often the consequence of their unacceptable solubility and dissolution rates, is an indisputable…”
Get full text
Journal Article -
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Quantitative analysis of endogenous compounds
Published in Journal of pharmaceutical and biomedical analysis (05-09-2016)“…•Quantification of endogenous analytes in biological matrices.•Presents an overview of the four approaches.•Summarize their applications, and compare their…”
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