Search Results - "Alamneh, Yonas"

Extracellular polymeric substance (EPS)-degrading enzymes reduce staphylococcal surface attachment and biocide resistance on pig skin in vivo by Kaplan, Jeffrey B, Mlynek, Kevin D, Hettiarachchi, Hashani, Alamneh, Yonas A, Biggemann, Lionel, Zurawski, Daniel V, Black, Chad C, Bane, Charles E, Kim, Robert K, Granick, Mark S

“…Staphylococcal extracellular polymeric substances (EPS) such as extracellular DNA (eDNA) and poly-N-acetylglucosamine surface polysaccharide (PNAG) mediate…”
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SPR741, an Antibiotic Adjuvant, Potentiates the In Vitro and In Vivo Activity of Rifampin against Clinically Relevant Extensively Drug-Resistant Acinetobacter baumannii by Zurawski, Daniel V, Reinhart, Alexandria A, Alamneh, Yonas A, Pucci, Michael J, Si, Yuanzheng, Abu-Taleb, Rania, Shearer, Jonathan P, Demons, Samandra T, Tyner, Stuart D, Lister, Troy

“…is responsible for 10% of all nosocomial infections and has >50% mortality rates when causing ventilator-associated pneumonia. In this proof-of-concept study,…”
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Longitudinal temperature measurement can determine humane endpoints in BALB/c mouse models of ESKAPEE infection by Dudis, Randal Scott, Wong, Ting Y., Escatte, Mariel G., Alamneh, Yonas A., Abu-Taleb, Rania, Su, Wanwen, Czintos, Christine, Fitzgerald, Timothy A., Le Breton, Yoann, Zurawski, Daniel V.

“…Antimicrobial resistance (AMR) is a worldwide problem, which is driving more preclinical research to find new treatments and countermeasures for drug-resistant…”
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Characterization of Acinetobacter baumannii Copper Resistance Reveals a Role in Virulence by Williams, Caitlin L, Neu, Heather M, Alamneh, Yonas A, Reddinger, Ryan M, Jacobs, Anna C, Singh, Shweta, Abu-Taleb, Rania, Michel, Sarah L J, Zurawski, Daniel V, Merrell, D Scott

“…is often highly drug-resistant and causes severe infections in compromised patients. These infections can be life threatening due to limited treatment options…”
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Validation of a Novel Murine Wound Model of Acinetobacter baumannii Infection by THOMPSON, Mitchell G, BLACK, Chad C, YILDIRIM, Suleyman, KIRKUP, Benjamin C, GREEN, Romanza K, HALL, Eric R, PALYS, Thomas J, ZURAWSKI, Daniel V, PAVLICEK, Rebecca L, HONNOLD, Cary L, WISE, Matthew C, ALAMNEH, Yonas A, MOON, Jay K, KESSLER, Jennifer L, YUANZHENG SI, WILLIAMS, Robert

“…OA  Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Skin and Soft Tissue Models for Acinetobacter baumannii Infection by Zurawski, Daniel V, Banerjee, Jaideep, Alamneh, Yonas A, Shearer, Jonathan P, Demons, Samandra T

“…Multidrug-resistant A. baumannii are important Gram-negative pathogens causing persistent wound infections in both wounded and burned victims, which often…”
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Evaluation of Gallium Citrate Formulations against a Multidrug-Resistant Strain of Klebsiella pneumoniae in a Murine Wound Model of Infection by Thompson, Mitchell G, Truong-Le, Vu, Alamneh, Yonas A, Black, Chad C, Anderl, Jeff, Honnold, Cary L, Pavlicek, Rebecca L, Abu-Taleb, Rania, Wise, Matthew C, Hall, Eric R, Wagar, Eric J, Patzer, Eric, Zurawski, Daniel V

“…Skin and soft tissue infections (SSTIs) are a common occurrence in health care facilities with a heightened risk for immunocompromised patients. Klebsiella…”
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Whole-cell vaccine candidates induce a protective response against virulent Acinetobacter baumannii by Dollery, Stephen J., Zurawski, Daniel V., Bushnell, Ruth V., Tobin, John K., Wiggins, Taralyn J., MacLeod, David A., Tasker, Naomi J. P. E. R., Alamneh, Yonas A., Abu-Taleb, Rania, Czintos, Christine M., Su, Wanwen, Escatte, Mariel G., Meeks, Heather N., Daly, Michael J., Tobin, Gregory J.

“…Acinetobacter baumannii causes multi-system diseases in both nosocomial settings and a pre-disposed general population. The bacterium is not only…”
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Modulation of cholinergic pathways and inflammatory mediators in blast-induced traumatic brain injury by Valiyaveettil, Manojkumar, Alamneh, Yonas A., Miller, Stacey-Ann, Hammamieh, Rasha, Arun, Peethambaran, Wang, Ying, Wei, Yanling, Oguntayo, Samuel, Long, Joseph B., Nambiar, Madhusoodana P.

“…► Blast exposure modulates cholinergic pathway. ► Levels of inflammatory mediators changes after blast injury. ► Blast exposure causes differential expression…”
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Minocycline and the SPR741 Adjuvant Are an Efficacious Antibacterial Combination for Acinetobacter baumannii Infections by Alamneh, Yonas A., Antonic, Vlado, Garry, Brittany, Pucci, Michael J., Abu-Taleb, Rania, Shearer, Jonathan P., Demons, Samandra T., Getnet, Derese, Swierczewski, Brett E., Lister, Troy, Zurawski, Daniel V.

“…Antibiotic resistance, when it comes to bacterial infections, is not a problem that is going to disappear anytime soon. With the lack of larger investment in…”
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Development of a Combat-Relevant Murine Model of Wound Mucormycosis: A Platform for the Pre-Clinical Investigation of Novel Therapeutics for Wound-Invasive Fungal Diseases by Samdavid Thanapaul, Rex J R, Alamneh, Yonas A, Finnegan, Daniel K, Antonic, Vlado, Abu-Taleb, Rania, Czintos, Christine, Boone, Dylan, Su, Wanwen, Sajja, Venkatasivasai S, Getnet, Derese, Roberds, Ashleigh, Walsh, Thomas J, Bobrov, Alexander G

“…Wound-invasive fungal diseases (WIFDs), especially mucormycosis, have emerged as life-threatening infections during recent military combat operations. Many…”
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Crossroads in the evaluation of paraoxonase 1 for protection against nerve agent and organophosphate toxicity by Valiyaveettil, Manojkumar, Alamneh, Yonas A., Doctor, Bhupendra P., Nambiar, Madhusoodana P.

“…► Paraoxonase 1 prophylaxis against nerve agent toxicity. ► In vitro and in vivo efficacy of paraoxonase 1 against organophosphates/nerve agents. ► Half-life…”
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Radiation-Inactivated Acinetobacter baumannii Vaccine Candidates by Dollery, Stephen J, Zurawski, Daniel V, Gaidamakova, Elena K, Matrosova, Vera Y, Tobin, John K, Wiggins, Taralyn J, Bushnell, Ruth V, MacLeod, David A, Alamneh, Yonas A, Abu-Taleb, Rania, Escatte, Mariel G, Meeks, Heather N, Daly, Michael J, Tobin, Gregory J

“…is a bacterial pathogen that is often multidrug-resistant (MDR) and causes a range of life-threatening illnesses, including pneumonia, septicemia, and wound…”
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Cytoskeletal protein α–II spectrin degradation in the brain of repeated blast exposed mice by Valiyaveettil, Manoj, Alamneh, Yonas A, Wang, Ying, Arun, Peethambaran, Oguntayo, Samuel, Wei, Yanling, Long, Joseph B, Nambiar, Madhusoodana P

“…Abstract Repeated blast exposures commonly induce traumatic brain injury (TBI) characterized by diffuse axonal injury (DAI). We hypothesized that degradation…”
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Rapid release of tissue enzymes into blood after blast exposure: potential use as biological dosimeters by Arun, Peethambaran, Oguntayo, Samuel, Alamneh, Yonas, Honnold, Cary, Wang, Ying, Valiyaveettil, Manojkumar, Long, Joseph B, Nambiar, Madhusoodana P

“…Explosive blast results in multiple organ injury and polytrauma, the intensity of which varies with the nature of the exposure, orientation, environment and…”
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Blast Waves Cause Immune System Dysfunction and Transient Bone Marrow Failure in a Mouse Model by Bergmann-Leitner, Elke S, Bobrov, Alexander G, Bolton, Jessica S, Rouse, Michael D, Heyburn, Lanier, Pavlovic, Radmila, Garry, Brittany I, Alamneh, Yonas, Long, Joseph, Swierczewski, Brett, Tyner, Stuart, Getnet, Derese, Sajja, Venkatasivasai S, Antonic, Vlado

“…Explosive devices, either conventional or improvised, are common sources of injuries during combat, civil unrest, and terror attacks, resulting in trauma from…”
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In vitro efficacy of paraoxonase 1 from multiple sources against various organophosphates by Valiyaveettil, Manojkumar, Alamneh, Yonas, Biggemann, Lionel, Soojhawon, Iswarduth, Farag, Heba A., Agrawal, Prashasthi, Doctor, Bhupendra P., Nambiar, Madhusoodana P.

“…Paraoxonase 1 (PON1) has been described as a potential catalytic bioscavenger due to its ability to hydrolyze organophosphate (OP) insecticides and nerve…”
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Optimization of a Lethal, Combat-Relevant Model of Sterile Inflammation in Mice for Drug Candidate Screening by Rios, Kariana E, Alamneh, Yonas, Werner, Lacie M, Leung, Clara, Pavlovic, Radmila, Abu-Taleb, Rania, Thanapaul, Rex J R S, Lee, Sunjoo, Hull, Dawn, Czintos, Christine, Su, Wanwen, Getnet, Derese, Antonic, Vlado, Bobrov, Alexander G

“…Extensive trauma, commonly seen in wounded military Service Members, often leads to a severe sterile inflammation termed systemic inflammatory response…”
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Extracellular polymeric substance by Kaplan, Jeffrey B, Mlynek, Kevin D, Hettiarachchi, Hashani, Alamneh, Yonas A, Biggemann, Lionel, Zurawski, Daniel V, Black, Chad C, Bane, Charles E, Kim, Robert K, Granick, Mark S

“…Staphylococcal extracellular polymeric substances (EPS) such as extracellular DNA (eDNA) and poly-N-acetylglucosamine surface polysaccharide (PNAG) mediate…”
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Impact of Blast Overpressure on the Pharmacokinetics of Various Antibiotics in Sprague Dawley Rats by Rios, Kariana E, Selig, Daniel J, Pavlovic, Radmila, Alamneh, Yonas, Vuong, Chau, Nadeau, Robert John, Pannone, Kristina M, Deluca, Jesse P, Long, Joseph B, Sajja, Venkatasivasai S, Tyner, Stuart, Antonic, Vlado, Getnet, Derese, Bobrov, Alexander G

“…ABSTRACT Introduction Combat injuries are complex and multimodal. Most injuries to the extremities occur because of explosive devices such as improvised…”
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