Search Results - "Alam, Md. Aftab"

Overcoming the Limitations of Therapeutic Strategies to Combat Pancreatic Cancer using Nanotechnology by Dhoundiyal, Shivang, Alam, Md Aftab

“…There is a significant unmet demand for the treatment of pancreatic cancer. Many patients do not make it to past five years after diagnosis. The effectiveness…”
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Calcium Dynamics of the Ventrolateral Preoptic GABAergic Neurons during Spontaneous Sleep-Waking and in Response to Homeostatic Sleep Demands by Kostin, Andrey, Alam, Md Aftab, Saevskiy, Anton, Yang, Chenyi, Golshani, Peyman, Alam, Md Noor

“…The ventrolateral preoptic area (VLPO) contains GABAergic sleep-active neurons. However, the extent to which these neurons are involved in expressing…”
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Advancements and Utilizations of Scaffolds in Tissue Engineering and Drug Delivery by Chauhan, Akash, Alam, Md Aftab, Kaur, Awaneet, Malviya, Rishabha

“…The drug development process requires a thorough understanding of the scaffold and its three-dimensional structure. Scaffolding is a technique for tissue…”
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Potential Neuroprotective Strategies using Smart Drug Delivery Systems for Alzheimer's Disease by Khan, Javed, Yadav, Shikha, Alam, Md Aftab

“…Alzheimer's disease (AD) is the most common neurological disorder, affecting more than 50 million individuals worldwide and causing gradual but progressive…”
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Neuronal activity in the preoptic hypothalamus during sleep deprivation and recovery sleep by Alam, Md Aftab, Kumar, Sunil, McGinty, Dennis, Alam, Md Noor, Szymusiak, Ronald

“…The preoptic hypothalamus is implicated in sleep regulation. Neurons in the median preoptic nucleus (MnPO) and the ventrolateral preoptic area (VLPO) have been…”
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Chronic Suppression of Hypothalamic Cell Proliferation and Neurogenesis Induces Aging-Like Changes in Sleep–Wake Organization in Young Mice by Kostin, Andrey, Alam, Md. Aftab, McGinty, Dennis, Szymusiak, Ronald, Alam, Md. Noor

“…Aging is associated with sleep–wake disruption, dampening of circadian amplitudes, and a reduced homeostatic sleep response. Aging is also associated with a…”
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Chronic Astrocytic TNFα Production in the Preoptic-Basal Forebrain Causes Aging-like Sleep-Wake Disturbances in Young Mice by Kostin, Andrey, Alam, Md Aftab, Saevskiy, Anton, Alam, Md Noor

“…Sleep disruption is a frequent problem of advancing age, often accompanied by low-grade chronic central and peripheral inflammation. We examined whether…”
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Activation of the Ventrolateral Preoptic Neurons Projecting to the Perifornical-Hypothalamic Area Promotes Sleep: DREADD Activation in Wild-Type Rats by Kostin, Andrey, Alam, Md Aftab, Saevskiy, Anton, McGinty, Dennis, Alam, Md Noor

“…The ventrolateral preoptic area (VLPO) predominantly contains sleep-active neurons and is involved in sleep regulation. The perifornical-hypothalamic area…”
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Design, Synthesis, and Cytotoxicity Evaluation of 3‐(5‐(3‐(aryl)‐1‐phenyl‐1H‐pyrazol‐4‐yl)‐1‐phenyl‐4,5‐dihydro‐1H‐pyrazol‐3‐yl)pyridine and 5‐(3‐(aryl)‐1‐phenyl‐1H‐pyrazol‐4‐yl)‐3‐(pyridin‐3‐yl)‐4,5‐dihydropyrazole‐1‐carbaldehyde Derivatives as Potential Anticancer Agents by Alam, Raquib, Alam, Md. Aftab, Panda, Amulya K., Rahisuddin

“…In an attempt to find bio‐active small molecules, a series of novel 3‐(5‐(3‐(aryl)‐1‐phenyl‐1H‐pyrazol‐4‐yl)‐1‐phenyl‐4,5‐dihydro‐1H‐pyrazol‐3‐yl)pyridine 5a–i…”
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A Brief Review of Radioactive Materials for Therapeutic and Diagnostic Purposes by Bharti, Manisha, Alam, Md Aftab, Rao, Gudhanti Siva Nago Koteswara, Sharma, Pramod Kumar

“…Radiation treatment has been advancing ever since the discovery of X-rays in 1895. The goal of radiotherapy is to shape the best isodose on the tumor volume…”
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Glutamic acid stimulation of the perifornical-lateral hypothalamic area promotes arousal and inhibits non-REM/REM sleep by Alam, Md. Aftab, Mallick, Birendra Nath

“…The orexinergic neurons, localized in the perifornical hypothalamic area (PeF), are active during waking and quiet during non-rapid eye movement (non-REM) and…”
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Improved oral efficacy of epirubicin through polymeric nanoparticles: pharmacodynamic and toxicological investigations by Tariq, Mohammad, Alam, Md Aftab, Singh, Anu T, Panda, Amulya K, Talegaonkar, Sushama

“…Epirubicin (EPI) elicits poor-oral bioavailability hence commercially available as injection for intravenous administration which follows a rapid increase and…”
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Immunotherapies landscape and associated inhibitors for the treatment of cervical cancer by Yadav, Agrima, Yadav, Shikha, Alam, Md. Aftab

“…Cervical cancer ranks as the fourth most common form of cancer worldwide. There is a large number of situations that may be examined in the developing world…”
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Disability and Popular Common Sense in India: Noun versus Adjective by Shahid, Mohd, Raza, Md. Shahid, Alam, Md. Aftab

“…Reflecting through the Indian experiences, a brief attempt is made to explore how disability as a noun takes shape in popular common sense "call names"…”
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Rutin-encapsulated chitosan nanoparticles targeted to the brain in the treatment of Cerebral Ischemia by Ahmad, Niyaz, Ahmad, Rizwan, Naqvi, Atta Abbas, Alam, Md Aftab, Ashafaq, Mohammad, Samim, Mohd, Iqbal, Zeenat, Ahmad, Farhan Jalees

“…Rutin, a potent antioxidant, has been reported to reduce the risk of ischemic disease. Our study aims to prepare rutin-encapsulated-chitosan nanoparticles…”
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Adult hypothalamic neurogenesis and sleep–wake dysfunction in aging by Kostin, Andrey, Alam, Md Aftab, McGinty, Dennis, Alam, Md Noor

“…Abstract In the mammalian brain, adult neurogenesis has been extensively studied in the hippocampal sub-granular zone and the sub-ventricular zone of the…”
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Biodegradable polymeric nanoparticles for oral delivery of epirubicin: In vitro, ex vivo, and in vivo investigations by Tariq, Mohammad, Alam, Md Aftab, Singh, Anu T, Iqbal, Zeenat, Panda, Amulya K, Talegaonkar, Sushama

“…Epirubicin (EPI) is an anthracycline antineoplastic agent, commercially available for intravenous administration only and its oral ingestion continues to…”
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Characteristics of sleep-active neurons in the medullary parafacial zone in rats by Alam, Md Aftab, Kostin, Andrey, Siegel, Jerome, McGinty, Dennis, Szymusiak, Ronald, Alam, Md Noor

“…Growing evidence supports a role for the medullary parafacial zone in non-rapid eye movement (non-REM) sleep regulation. Cell-body specific lesions of the…”
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Enhancement of oral bioavailability of doxorubicin through surface modified biodegradable polymeric nanoparticles by Ahmad, Niyaz, Ahmad, Rizwan, Alam, Md Aftab, Ahmad, Farhan Jalees

“…Background Doxorubicin hydrochloride (DOX·HCl), an anthracycline glycoside antibiotic, exhibits low oral bioavailability due to active efflux from intestinal…”
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Advancements in Biotechnology and Stem Cell Therapies for Breast Cancer Patients by Dhoundiyal, Shivang, Alam, Md Aftab

“…This comprehensive review article examines the integration of biotechnology and stem cell therapy in breast cancer diagnosis and treatment. It discusses the…”
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