Search Results - "Alam, J J"

Directed flow of charm quarks as a witness of the initial strong magnetic field in ultra-relativistic heavy ion collisions by Das, Santosh K., Plumari, S., Chatterjee, S., Alam, J., Scardina, F., Greco, V.

“…Ultra-relativistic Heavy-Ion Collision (HIC) generates very strong initial magnetic field (B→) inducing a vorticity in the reaction plane. The high B→…”
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Wnt addiction of genetically defined cancers reversed by PORCN inhibition by Madan, B, Ke, Z, Harmston, N, Ho, S Y, Frois, A O, Alam, J, Jeyaraj, D A, Pendharkar, V, Ghosh, K, Virshup, I H, Manoharan, V, Ong, E H Q, Sangthongpitag, K, Hill, J, Petretto, E, Keller, T H, Lee, M A, Matter, A, Virshup, D M

“…Enhanced sensitivity to Wnts is an emerging hallmark of a subset of cancers, defined in part by mutations regulating the abundance of their receptors. Whether…”
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P38α MAPK Signaling-A Robust Therapeutic Target for Rab5-Mediated Neurodegenerative Disease by Germann, Ursula A, Alam, John J

“…Multifactorial pathologies, involving one or more aggregated protein(s) and neuroinflammation are common in major neurodegenerative diseases, such as…”
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Drug development targeting degeneration of the basal forebrain cholinergic system: its time has come by Alam, John J, Nixon, Ralph A

“…Keywords: Cholinergic degeneration, Basal forebrain, Rab5, Neflamapimod, p38[alpha], Alzheimer's disease, Dementia with Lewy bodies…”
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Continuous administration of a p38α inhibitor during the subacute phase after transient ischemia-induced stroke in the rat promotes dose-dependent functional recovery accompanied by increase in brain BDNF protein level by Alam, John J, Krakovsky, Michael, Germann, Ursula, Levy, Aharon

“…There is unmet need for effective stroke therapies. Numerous neuroprotection attempts for acute cerebral ischemia have failed and as a result there is growing…”
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Correction: Drug development targeting degeneration of the basal forebrain cholinergic system: its time has come by Alam, John J, Nixon, Ralph A

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FKS Mutant Candida glabrata: Risk Factors and Outcomes in Patients With Candidemia by Beyda, Nicholas D., John, Julie, Kilic, Abdullah, Alam, Mohammad J., Lasco, Todd M., Garey, Kevin W.

“…Background. Echinocandins are recommended for Candia glabrata candidemia. Mutations in the FKS1 and FKS2 genes are associated with echinocandin resistance. Few…”
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Cylindrical micro and nanowires: Fabrication, properties and applications by Alam, J., Bran, C., Chiriac, H., Lupu, N., Óvári, T.A., Panina, L.V., Rodionova, V., Varga, R., Vazquez, M., Zhukov, A.

“…•Cylindrical magnetic nanowires offer novel expectations as compared to nanostrips.•Glass-coated nanowires provide new application opportunities in sensing and…”
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Occurrence and Characteristics of Class 1 and 2 Integrons in Pseudomonas aeruginosa Isolates from Patients in Southern China by Xu, Zhenbo, Li, Lin, Shirtliff, Mark E, Alam, M.J, Yamasaki, Shinji, Shi, Lei

“…Class 1 and 2 integrons were detected in 45.8% (54/118) and 19.5% (23/118) of our tested Pseudomonas aeruginosa isolates, respectively. Three strains were…”
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Community Energy Storage for Neutral Voltage Rise Mitigation in Four-Wire Multigrounded LV Feeders With Unbalanced Solar PV Allocation by Alam, M. J. E., Muttaqi, Kashem M., Sutanto, Danny

“…The traditional neutral voltage problem in low-voltage (LV) four-wire multigrounded distribution networks can be aggravated due to an unbalanced allocation of…”
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Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration by Jiang, Ying, Alam, John J., Gomperts, Stephen N., Maruff, Paul, Lemstra, Afina W., Germann, Ursula A., Stavrides, Philip H., Darji, Sandipkumar, Malampati, Sandeep, Peddy, James, Bleiwas, Cynthia, Pawlik, Monika, Pensalfini, Anna, Yang, Dun-Sheng, Subbanna, Shivakumar, Basavarajappa, Balapal S., Smiley, John F., Gardner, Amanda, Blackburn, Kelly, Chu, Hui-May, Prins, Niels D., Teunissen, Charlotte E., Harrison, John E., Scheltens, Philip, Nixon, Ralph A.

“…The endosome-associated GTPase Rab5 is a central player in the molecular mechanisms leading to degeneration of basal forebrain cholinergic neurons (BFCN), a…”
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Identifying value chain trade-offs from fruit and vegetable aggregation services in Bangladesh using a system dynamics approach by Choudhury, Dipok K, Cooper, Gregory S, Rich, Karl M, Shankar, Bhavani, Sadek, Sadman, Ratna, Nazmun N, Kadiyala, Suneetha, Alam, Mohammad J

“…Significant progress has been made in cereal production in Bangladesh due to an agricultural policy environment that prioritizes the productivity of staple…”
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Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway by Alam, J, Cook, J L

“…The heme oxygenase-1 (HO-1) enzyme catalyzes the rate-limiting reaction in the catabolism of heme yielding products with pleiotropic, but ultimately,…”
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Seasonal simulation of water, salinity and nitrate dynamics under drip irrigated mandarin (Citrus reticulata) and assessing management options for drainage and nitrate leaching by Phogat, V., Skewes, M.A., Cox, J.W., Sanderson, G., Alam, J., Šimůnek, J.

“…•The seasonal water, salinity and nitrate distribution in soil was simulated by HYDRUS-2D.•Deep drainage accounts for 33.5% and water uptake 49% of applied…”
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Influence of Al3+ doping on structural and magnetic properties of CoFe2-xAlxO4 Ferrite nanoparticles by Dipesh, D. Neupane, Wang, L., Adhikari, H., Alam, J., Mishra, S.R.

“…A series of Al3+ substituted CoFe2-xAlxO4 (x = 0.0 to 0.9) ferrite nanoparticles were synthesized via autocombustion method. XRD data show that all the samples…”
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Is there co-movement of agricultural commodities futures prices and crude oil? by Natanelov, Valeri, Alam, Mohammad J., McKenzie, Andrew M., Van Huylenbroeck, Guido

“…Even though significant attempts have appeared in literature, the current perception of co-movement of commodity prices appear inadequate and static. In…”
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Neflamapimod: Clinical Phase 2b-Ready Oral Small Molecule Inhibitor of p38α to Reverse Synaptic Dysfunction in Early Alzheimer's Disease by Alam, J, Blackburn, K, Patrick, D

“…Neflamapimod (previously code named VX-745) is a clinical phase 2b-ready highly specific inhibitor of the intra-cellular enzyme p38 mitogen activated protein…”
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A phase 2 double-blind placebo-controlled 24-week treatment clinical study of the p38 alpha kinase inhibitor neflamapimod in mild Alzheimer’s disease by Prins, Niels D, Harrison, John E, Chu, Hui-May, Blackburn, Kelly, Alam, John J, Scheltens, Philip, Rowell, Zarate, Norden, Van

“…Abstract Background In preclinical studies, p38⍺ kinase is implicated in Alzheimer’s disease (AD) pathogenesis. In animal models, it mediates impaired synaptic…”
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Excellent soft magnetic properties in Co-based amorphous alloys after heat treatment at temperatures near the crystallization onset by Nematov, M.G., Kolesnikova, V., Evstigneeva, S.A., Alam, J., Yudanov, N.A., Samokhvalov, A.A., Andreev, N., Podgornaya, S.V., Soldatov, I., Schaefer, R., Rodionova, V., Panina, L.V.

“…•Heating Co-rich amorphous microwires at temperatures near crystallization onset Tcr causes a sharp drop in magnetostriction•Amorphous phase decomposition at…”
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Structural and spectroscopic analysis of HoMn2O5 multiferroics by Ahmad, Javed, Afzal, Vardah, Nissar, Umair, Bukhari, S H, Jamil, M T, Khan, J Alam, Abbas, Hammad, Hina, Maryam

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