Search Results - "Alakuijala, L"

Transgenic mice over-producing putrescine in their tissues do not convert the diamine into higher polyamines by HALMEKYTÖ, M, ALHONEN, L, ALAKUIJALA, L, JÄNNE, J

“…We recently described a transgenic mouse line over-expressing the human ornithine decarboxylase gene virtually in all tissues. Despite strikingly elevated…”
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Elevated seizure threshold and impaired spatial learning in transgenic mice with putrescine overproduction in the brain by Halonen, T, Sivenius, J, Miettinen, R, Halmekytö, M, Kauppinen, R, Sinervirta, R, Alakuijala, L, Alhonen, L, MacDonald, E, Jänne, J

“…We have studied the role of putrescine by using transgenic mouse lines overexpressing the human ornithine decarboxylase gene in most of their tissues. The…”
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Methionine toxicity in the rat in relation to hepatic accumulation of S-adenosylmethionine: prevention by dietary stimulation of the hepatic transsulfuration pathway by Regina, M, Korhonen, V P, Smith, T K, Alakuijala, L, Eloranta, T O

“…Rats were fed toxic levels of methionine with or without simultaneous dietary supplements of glycine and serine. Feed intake, growth rate, and metabolite…”
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1-Aminooxy-3-aminopropane reversibly prevents the proliferation of cultured baby hamster kidney cells by interfering with polyamine synthesis by Hyvönen, T, Alakuijala, L, Andersson, L, Khomutov, A R, Khomutov, R M, Eloranta, T O

“…The effects on cultured baby hamster kidney cells of 1-aminooxy-3-aminopropane, a potent new inhibitor of mammalian ornithine and S-adenosylmethionine…”
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Differential effects of sepsis and trauma on urinary excretion of polyamines by Pöyhönen, M J, Takala, J A, Pitkänen, O, Kari, A, Alakuijala, L A, Eloranta, T O

“…Urinary excretion of polyamines increases in patients with trauma and infection. To separate the effect of infection from the general metabolic response to…”
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Free amino acid levels in oral fluids of normal subjects and patients with periodontal disease by Syrjänen, S M, Alakuijala, L, Alakuijala, P, Markkanen, S O, Markkanen, H

“…The content of free amino acids in submandibular, parotid and whole saliva and in gingival fluid was measured by automatic analyser in patients with…”
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Urinary excretion of polyamines: importance of circadian rhythm, age, sex, menstrual cycle, weight, and creatinine excretion by Pöyhönen, MJ, Uusitalo, UM, Kari, A, Takala, JA, Alakuijala, LA, Eloranta, TO

“…The urinary excretion of putrescine, spermidine, spermine, and N1- and N8-acetylspermidines was measured in 95 volunteers. The 24-h excretion, split in four…”
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Polyamine Excretion in Depleted Patients With Gastrointestinal Malignancy: Effect of Perioperative Nutrition and Tumor Removal by Pöyhönen, Mikko J., Takala, Jukka A., Pitkänen, Otto, Kari, Aarno, Alhava, Esko, Alakuijala, Lsa A., Eloranta, Terho O.

“…Polyamines, synthesized by all mammalian cells, are involved in protein and energy metabolism. We measured urinary excretion of polyamines, putrescine,…”
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Increased urinary polyamine excretion after starting a very low calorie diet by Uusitupa, M, Pöyhönen, M, Sarlund, H, Laakso, M, Kari, A, Helenius, T, Alakuijala, L, Eloranta, T

“…Urinary polyamine excretion has been suggested to reflect hypermetabolism or catabolism in different illnesses. In the present study, the excretion of urinary…”
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Metabolic responses to exercise in the racehorse: changes in plasma alanine concentration by Pösö, A R, Soveri, T, Alaviuhkola, M, Lindqvist, L, Alakuijala, L, Mäenpää, P H, Oksanen, H E

“…Previous studies in humans have shown that alanine is released from the skeletal muscle in proportion to the work load. We have measured plasma alanine and…”
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Urinary excretion of polyamines in patients with surgical and accidental trauma: effect of total parenteral nutrition by Pöyhönen, M J, Takala, J A, Pitkänen, O, Kari, A, Alhava, E, Alakuijala, L A, Eloranta, T O

“…Excretion of polyamines first increases and then decreases in patients with multiple trauma receiving total parenteral nutrition (TPN). To separate the effects…”
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Effects of dietary polyamine precursors on the metabolism and tissue concentrations of amino acids in the rat by Smith, T K, Lindqvist, L, Alakuijala, L, Eloranta, T O

“…Experiments were conducted to determine the effects of dietary supplements of amino acid precursors of polyamines on amino acid metabolism in the rat in order…”
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