Search Results - "Alajmi, Mohammed F."

In silico exploration of deep-sea fungal metabolites as inhibitor of Ebola and Marburg VP35 and VP40 by Alanzi, Abdullah R, Alajmi, Mohammed F, Al-Dosari, Mohammed S, Parvez, Mohammad K, Alqahtani, Moneerah J

“…VP30 and VP40 proteins of Ebola and Marburg viruses have been recognized as potential targets for antiviral drug development due to their essential roles in…”
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Plant-derived antiviral drugs as novel hepatitis B virus inhibitors: Cell culture and molecular docking study by Parvez, Mohammad K., Tabish Rehman, Md, Alam, Perwez, Al-Dosari, Mohammed S., Alqasoumi, Saleh I., Alajmi, Mohammed F.

“…Despite high anti-HBV efficacies, while the nucleoside analogs (e.g., lamivudine) lead to the emergence of drug-resistance, interferons (e.g., IFN-α causes…”
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Determination of chloramphenicol in biological matrices by solid-phase membrane micro-tip extraction and capillary electrophoresis by Hussain, Afzal, Alajmi, Mohammed F., Ali, Imran

“…Solid‐phase membrane micro‐tip extraction (SPMMTE) and capillary electrophoresis (CE) methods were developed and validated for analysis of chloramphenicol in…”
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Structural Analysis and Conformational Dynamics of STN1 Gene Mutations Involved in Coat Plus Syndrome by Amir, Mohd, Mohammad, Taj, Kumar, Vijay, Alajmi, Mohammed F, Rehman, Md Tabish, Hussain, Afzal, Alam, Perwez, Dohare, Ravins, Islam, Asimul, Ahmad, Faizan, Hassan, Md Imtaiyaz

“…The human CST complex (CTC1-STN1-TEN1) is associated with telomere functions including genome stability. We have systemically analyzed the sequence of STN and…”
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Inhibition of hepatitis B virus activities by Rhazya stricta ‑derived acacetin and acetyl‑β‑carboline by Parvez, Mohammad, Alhowiriny, Tawfeq, Al‑Dosari, Mohammed, Amina, Musarat, Rehman, Md Tabish, Al‑Yousef, Hanan, Alanzi, Abdullah, Alajmi, Mohammed

“…Hepatitis B virus (HBV) causes acute and chronic liver diseases, leading to cirrhosis and hepatocellular carcinoma. Although direct-acting nucleoside analogs,…”
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New terpenic and phenolic compounds from Suaeda monoica reverse oxidative and apoptotic damages in human endothelial cells by Parvez, Mohammad K., Al-Dosari, Mohammed S., Tabish Rehman, Md, Alajmi, Mohammed F., Alqahtani, Ali S., AlSaid, Mansour S.

“…Elevation in hyperglycemia-associated methylglyoxal level can trigger vascular endothelial cells oxidative stress and apoptosis. The present work assesses the…”
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Corrigendum to “New terpenic and phenolic compounds from Suaeda monoica reverse oxidative and apoptotic damages in human endothelial cells”. [Saudi Pharm. J. 29(10) (2021) 1102–1111] by Parvez, Mohammad K., Al-Dosari, Mohammed S., Tabish Rehman, Md, Alajmi, Mohammed F., Alqahtani, Ali S., AlSaid, Mansour S.

“…[This corrects the article DOI: 10.1016/j.jsps.2021.08.007.]…”
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Oncoglabrinol C, a new flavan from Oncocalyx glabratus protects endothelial cells against oxidative stress and apoptosis, and modulates hepatic CYP3A4 activity by Parvez, Mohammad K., Al-Dosari, Mohammed S., Ahmed, Sarfaraz, Rehman, Md. Tabish, Al-Rehaily, Adnan J., Alajmi, Mohammed F.

“…Active herbal or natural compounds have high chemical diversity and specificity than synthetic drugs. Recently, we have validated the hypoglycemic salutation…”
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Theoretical and experimental study on lipophilicity and wound healing activity of ginger compounds by Bakht, Mohammed Afroz, Alajmi, Mohammed F., Alam, Perwez, Alam, Aftab, Alam, Prawez, Aljarba, Tariq Mohammed

“…Objective:To correlate the chromatographic and computational method to calculate lipophilicity of selected ginger compounds and to observe the effects of log P…”
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Functional implications of pH-induced conformational changes in the Sphingosine kinase 1 by Gupta, Preeti, Khan, Faez Iqbal, Roy, Sonam, Anwar, Saleha, Dahiya, Rashmi, Alajmi, Mohammed F., Hussain, Afzal, Rehman, Md. Tabish, Lai, Dakun, Hassan, Md. Imtaiyaz

“…Sphingosine kinase 1 (SphK1) catalyzes the conversion of sphingosine to sphingosine-1-phosphate that acts as a bioactive signalling molecule, and regulates…”
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The anti‐hepatitis B virus therapeutic potential of anthraquinones derived from Aloe vera by Parvez, Mohammad K., Al‐Dosari, Mohammed S., Alam, Perwez, Rehman, MdTabish, Alajmi, Mohammed F., Alqahtani, Ali S.

“…Although the approved hepatitis B virus (HBV)‐polymerase inhibitors (e.g., lamivudine) often lead to drug‐resistance, several natural products have shown…”
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Molecular docking and ADMET studies of halogenated metabolites from marine sponges as inhibitors of wild-type and mutants PBP2 in Neisseria gonorrhoeae by Alanzi, Abdullah R, Alajmi, Mohammed F, Alqahtani, Moneerah J

“…Gonorrhoea is a sexually transmitted infection (STI) caused by the bacteria . Gonorrhoea symptoms can vary, although roughly 50% of women and 10% of men…”
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Identification and evaluation of glutathione conjugate gamma-l-glutamyl-l-cysteine for improved drug delivery to the brain by Fatima, Saman, Mohammad, Taj, Jairajpuri, Deeba Shamim, Rehman, Md Tabish, Hussain, Afzal, Samim, Mohammed, Ahmad, Farhan Jalees, Alajmi, Mohammed F., Hassan, Md. Imtaiyaz

“…Glutathione (GU), an endogenous antioxidant tripeptide, is frequently transferred in the human brain through N-methyl-d-aspartate receptor (NMDAR), profusely…”
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Evaluation of pyrazolopyrimidine derivatives as microtubule affinity regulating kinase 4 inhibitors: Towards therapeutic management of Alzheimer's disease by Naqvi, Ahmad Abu Turab, Jairajpuri, Deeba Shamim, Noman, Omar Mohammed Ali, Hussain, Afzal, Islam, Asimul, Ahmad, Faizan, Alajmi, Mohammed F., Hassan, Md. Imtaiyaz

“…Microtubule affinity regulating kinase 4 (MARK4) plays essential role in the tau-assisted regulation of microtubule dynamics. Over expression of MARK4 causes…”
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Chiral HPLC Separation and Modeling of Four Stereomers of DL-Leucine-DL-Tryptophan Dipeptide on Amylose Chiral Column by Alajmi, Mohammed F., Hussain, Afzal, Suhail, Mohd, Mukhtar, Sofi Danish, Sahoo, Dibya Ranjan, Asnin, Leonid, Ali, Imran

“…Chiral high‐performance liquid chromatography (HPLC) separation and modeling of four stereomers of DL‐leucine‐tryptophan DL‐dipeptide on AmyCoat‐RP column are…”
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Inhibition of hepatitis B virus activities by Rhazya stricta-derived acacetin and acetyl-[beta]-carboline by Parvez, Mohammad K, Alhowiriny, Tawfeq A, Dosari, Mohammed S. Al, Amina, Musarat, Rehman, MD Tabish, Yousef, Hanan M. Al, Alanzi, Abdullah R, Alajmi, Mohammed F

“…Hepatitis B virus (HBV) causes acute and chronic liver diseases, leading to cirrhosis and hepatocellular carcinoma. Although direct-acting nucleoside analogs,…”
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Cover Image, Volume 28, Issue 9 by Alajmi, Mohammed F., Hussain, Afzal, Suhail, Mohd, Mukhtar, Sofi Danish, Ranjan Sahoo, Dibya, Asnin, Leonid, Ali, Imran

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