Search Results - "Alag, Reema"

Release of frustration drives corneal amyloid disaggregation by brain chaperone by Low, Jia Yi Kimberly, Shi, Xiangyan, Anandalakshmi, Venkatraman, Neo, Dawn, Peh, Gary Swee Lim, Koh, Siew Kwan, Zhou, Lei, Abdul Rahim, M. K., Boo, Ketti, Lee, JiaXuan, Mohanram, Harini, Alag, Reema, Mu, Yuguang, Mehta, Jodhbir S., Pervushin, Konstantin

“…TGFBI-related corneal dystrophy (CD) is characterized by the accumulation of insoluble protein deposits in the corneal tissues, eventually leading to…”
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Structural Insights into Substrate Binding by PvFKBP35, a Peptidylprolyl cis-trans Isomerase from the Human Malarial Parasite Plasmodium vivax by Alag, Reema, Balakrishna, Asha Manikkoth, Rajan, Sreekanth, Qureshi, Insaf A, Shin, Joon, Lescar, Julien, Grüber, Gerhard, Yoon, Ho Sup

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Mechanistic insights into non-immunosuppressive immunophilin ligands as potential antimalarial therapeutics by Yoon, Ho Sup, Alag, Reema, Kang, Congbao, Ye, Hong, Kotaka, Masayo, Qureshi, Insaf A, Bharatham, Nagakumar, Shin, Joon, Bozdech, Zbynek, Preiser, Peter, Lescar, Julien

“…Clinical background The immunosuppressive drug FK506 reveals an antimalarial activity. The mechanism of the drug action involves the molecular interaction with…”
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In vivo liquid–liquid phase separation protects amyloidogenic and aggregation‐prone peptides during overexpression in Escherichia coli by Gabryelczyk, Bartosz, Alag, Reema, Philips, Margaret, Low, Kimberly, Venkatraman, Anandalakshmi, Kannaian, Bhuvaneswari, Shi, Xiangyan, Linder, Markus, Pervushin, Konstantin, Miserez, Ali

“…Studying pathogenic effects of amyloids requires homogeneous amyloidogenic peptide samples. Recombinant production of these peptides is challenging due to…”
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NMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodium vivax FKBP35 by Alag, Reema, Qureshi, Insaf A., Bharatham, Nagakumar, Shin, Joon, Lescar, Julien, Yoon, Ho Sup

“…The emergence of drug‐resistant malaria parasites is the major threat to effective malaria control, prompting a search for novel compounds with mechanisms of…”
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Crystallographic structure of the tetratricopeptide repeat domain of Plasmodium falciparum FKBP35 and its molecular interaction with Hsp90 C‐terminal pentapeptide by Alag, Reema, Bharatham, Nagakumar, Dong, Aiping, Hills, Tanya, Harikishore, Amaravadhi, Widjaja, Anissa Anindya, Shochat, Susana Geifman, Hui, Raymond, Yoon, Ho Sup

“…Plasmodium falciparum FK506‐binding protein 35 (PfFKBP35) that binds to FK506 contains a conserved tetratricopeptide repeat (TPR) domain. Several known TPR…”
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Structural Insights into Substrate Binding by Pv FKBP35, a Peptidylprolyl cis-trans Isomerase from the Human Malarial Parasite Plasmodium vivax by Alag, Reema, Balakrishna, Asha Manikkoth, Rajan, Sreekanth, Qureshi, Insaf A., Shin, Joon, Lescar, Julien, Grüber, Gerhard, Yoon, Ho Sup

“…ABSTRACT The immunosuppressive drug FK506 binding proteins (FKBPs), an immunophilin family with the immunosuppressive drug FK506 binding property, exhibit…”
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Crystal Structure of the FK506 Binding Domain of Plasmodium falciparum FKBP35 in Complex with FK506 by Kotaka, Masayo, Ye, Hong, Alag, Reema, Hu, Guangan, Bozdech, Zbynek, Preiser, Peter Rainer, Yoon, Ho Sup, Lescar, Julien

“…The emergence of multi-drug-resistant strains of Plasmodium parasites has prompted the search for alternative therapeutic strategies for combating malaria. One…”
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NMR assignments of the FK506-binding domain of FK506-binding protein 35 from Plasmodium vivax by Alag, Reema, Shin, Joon, Yoon, Ho Sup

“…PvFKBP35 is a member of the FK506 binding protein family (FKBP) from Plasmodium vivax . The FK506-binding domain of PvFKBP35 shows a canonical peptidylprolyl…”
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Crystal Structure of the FK506 Binding Domain of Plasmodium falciparum FKBP35 in Complex with FK506 super([dagger]) super([dagger]) by Bozdech, Zbynek, Preiser, Peter Rainer, Ye, Hong, Lescar, Julien, Alag, Reema, Hu, Guangan, Kotaka, Masayo, Yoon, Ho Sup

“…The emergence of multi-drug-resistant strains of Plasmodium parasites has prompted the search for alternative therapeutic strategies for combating malaria. One…”
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