Search Results - "Alachkar, Nissrin"

Variability of the innate immune response is globally constrained by transcriptional bursting by Alachkar, Nissrin, Norton, Dale, Wolkensdorfer, Zsofia, Muldoon, Mark, Paszek, Pawel

“…Transcription of almost all mammalian genes occurs in stochastic bursts, however the fundamental control mechanisms that allow appropriate single-cell…”
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Automating kidney transplant diagnostics by Alachkar, Nissrin, Alachkar, Nada

“…Diagnosis of kidney allograft rejection remains complex and somewhat subjective; but an automated version of the gold-standard Banff classification could…”
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Understanding Heterogeneity of Gene Expression in the Innate Immune System Through Mathematical Modelling by Alachkar, Nissrin

“…Mammalian gene transcription is rigorously regulated through various complex mechanisms to ensure accuracy and prevent errors in the synthesis of RNA…”
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Preservation of circadian rhythms by the protein folding chaperone, BiP by Pickard, Adam, Chang, Joan, Alachkar, Nissrin, Calverley, Ben, Garva, Richa, Arvan, Peter, Meng, Qing-Jun, Kadler, Karl E.

“…ABSTRACT Dysregulation of collagen synthesis is associated with disease progression in cancer and fibrosis. Collagen synthesis is coordinated with the…”
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Gene-Specific Linear Trends Constrain Transcriptional Variability of the Toll-like Receptor Signaling by Bagnall, James, Rowe, William, Alachkar, Nissrin, Roberts, James, England, Hazel, Clark, Christopher, Platt, Mark, Jackson, Dean A, Muldoon, Mark, Paszek, Pawel

“…Single-cell gene expression is inherently variable, but how this variability is controlled in response to stimulation remains unclear. Here, we use single-cell…”
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