Search Results - "Alabdullah, Muslim L."
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RAD50 deficiency is a predictor of platinum sensitivity in sporadic epithelial ovarian cancers
Published in Molecular biomedicine (30-12-2020)“…Intrinsic or acquired resistance seriously limits the use of platinating agents in advanced epithelial ovarian cancers. Increased DNA repair capacity is a key…”
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Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers
Published in Biomedicines (08-01-2021)“…Platinum resistance seriously impacts on the survival outcomes of patients with ovarian cancers. Platinum-induced DNA damage is processed through DNA repair…”
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Molecular disruption of DNA polymerase β for platinum sensitisation and synthetic lethality in epithelial ovarian cancers
Published in Oncogene (08-04-2021)“…Targeting PARP1 [Poly(ADP-Ribose) Polymerase 1] for synthetic lethality is a new strategy for BRCA germ-line mutated or platinum sensitive ovarian cancers…”
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Molecular disruption of DNA polymerase [beta] for platinum sensitisation and synthetic lethality in epithelial ovarian cancers
Published in Oncogene (08-04-2021)“…Targeting PARP1 [Poly(ADP-Ribose) Polymerase 1] for synthetic lethality is a new strategy for BRCA germ-line mutated or platinum sensitive ovarian cancers…”
Get full text
Journal Article