Search Results - "Alaamery, Manal A"

DNA-Based Nanobiosensors as an Emerging Platform for Detection of Disease by Abu-Salah, Khalid M, Zourob, Mohammed M, Mouffouk, Fouzi, Alrokayan, Salman A, Alaamery, Manal A, Ansari, Anees A

“…Detection of disease at an early stage is one of the biggest challenges in medicine. Different disciplines of science are working together in this regard. The…”
Get full text

Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast by Roux, Antoine E, Leroux, Alexandre, Alaamery, Manal A, Hoffman, Charles S, Chartrand, Pascal, Ferbeyre, Gerardo, Rokeach, Luis A

“…Glucose is the preferred carbon and energy source in prokaryotes, unicellular eukaryotes, and metazoans. However, excess of glucose has been associated with…”
Get full text

Schizosaccharomyces pombe Hsp90/Git10 is required for glucose/cAMP signaling by Alaamery, M.A, Hoffman, C.S

“…The fission yeast Schizosaccharomyces pombe senses environmental glucose through a cAMP-signaling pathway. Elevated cAMP levels activate protein kinase A (PKA)…”
Get full text

Identification and characterization of a potent and biologically-active PDE4/7 inhibitor via fission yeast-based assays by de Medeiros, Ana Santos, Wyman, Arlene R., Alaamery, Manal A., Allain, Christina, Ivey, F. Douglas, Wang, Lili, Le, Hai, Morken, James P., Habara, Alawi, Le, Cuong, Cui, Shuaiying, Lerner, Adam, Hoffman, Charles S.

“…We previously constructed a collection of fission yeast strains that express various mammalian cyclic nucleotide phosphodiesterases (PDEs) and developed a…”
Get full text

Anti-inflammatory effects of novel barbituric acid derivatives in T lymphocytes by Xu, Chenjia, Wyman, Arlene R., Alaamery, Manal A., Argueta, Shannon A., Ivey, F. Douglas, Meyers, John A., Lerner, Adam, Burdo, Tricia H., Connolly, Timothy, Hoffman, Charles S., Chiles, Thomas C.

“…We have used a high throughput small molecule screen, using a fission yeast-based assay, to identify novel phosphodiesterase 7 (PDE7) inhibitors. One of the…”
Get full text

New classes of PDE7 inhibitors identified by a fission yeast-based HTS by Alaamery, Manal A, Wyman, Arlene R, Ivey, F Douglas, Allain, Christina, Demirbas, Didem, Wang, Lili, Ceyhan, Ozge, Hoffman, Charles S

“…Studies of the phosphodiesterase PDE7 family are impeded by there being only one commercially available PDE7 inhibitor, BRL50481. The authors have employed a…”
Get more information

Pro-Aging Effects of Glucose Signaling through a G Protein-Coupled Glucose Receptor in Fission Yeast: e1000408 by Roux, Antoine E, Leroux, Alexandre, Alaamery, Manal A, Hoffman, Charles S, Chartrand, Pascal, Ferbeyre, Gerardo, Rokeach, Luis A

“…Glucose is the preferred carbon and energy source in prokaryotes, unicellular eukaryotes, and metazoans. However, excess of glucose has been associated with…”
Get full text