Search Results - "AlSadhan, Ishraq"
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1
How to measure and evaluate binding affinities
Published in eLife (06-08-2020)“…Quantitative measurements of biomolecule associations are central to biological understanding and are needed to build and test predictive and mechanistic…”
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Journal Article -
2
Differential catalytic promiscuity of the alkaline phosphatase superfamily bimetallo core reveals mechanistic features underlying enzyme evolution
Published in The Journal of biological chemistry (22-12-2017)“…Members of enzyme superfamilies specialize in different reactions but often exhibit catalytic promiscuity for one another’s reactions, consistent with…”
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Journal Article -
3
Pseudouridine and N6-methyladenosine modifications weaken PUF protein/RNA interactions
Published in RNA (Cambridge) (01-05-2017)“…RNA modifications are ubiquitous in biology, with over 100 distinct modifications. While the vast majority were identified and characterized on abundant…”
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Journal Article -
4
Pseudouridine and N 6 -methyladenosine modifications weaken PUF protein/RNA interactions
Published in RNA (Cambridge) (01-05-2017)“…RNA modifications are ubiquitous in biology, with over 100 distinct modifications. While the vast majority were identified and characterized on abundant…”
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Journal Article -
5
Mechanistic and Evolutionary Insights from Comparative Enzymology of Phosphomonoesterases and Phosphodiesterases across the Alkaline Phosphatase Superfamily
Published in Journal of the American Chemical Society (02-11-2016)“…Naively one might have expected an early division between phosphate monoesterases and diesterases of the alkaline phosphatase (AP) superfamily. On the…”
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Journal Article -
6
Pseudouridine and N super(6)-methyladenosine modifications weaken PUF protein/RNA interactions
Published in RNA (Cambridge) (01-05-2017)“…RNA modifications are ubiquitous in biology, with over 100 distinct modifications. While the vast majority were identified and characterized on abundant…”
Get full text
Journal Article