Search Results - "AlMesfer, Saleh"
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MDM2 inhibitors-mediated disruption of mitochondrial metabolism: A novel therapeutic strategy for retinoblastoma
Published in Frontiers in oncology (20-10-2022)“…MDM2 is the principal inhibitor of p53, and MDM2 inhibitors can disrupt the physical interaction between MDM2 and p53. The half-life of p53 is very short in…”
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State of the Art of Pharmacological Activators of p53 in Ocular Malignancies
Published in Cancers (12-07-2023)“…The pivotal role of p53 in the regulation of a vast array of cellular functions has been the subject of extensive research. The biological activity of p53 is…”
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Bilateral Retinoblastoma Presenting in an in vitro Fertilization Infant with Retinopathy of Prematurity
Published in Case reports in ophthalmology (01-01-2021)“…Retinopathy of prematurity (ROP) and retinoblastoma (RB) are well-described entities in premature babies. Although their pathogeneses are different, with ROP…”
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A Novel Technique Using Paretic Superior Rectus as a Globe Suspender for Monocular Elevation Deficiency
Published in Curēus (Palo Alto, CA) (02-10-2023)“…Surgical innovations in strabismus provide opportunities to improve visual function, eye alignment, and cosmesis in rare pediatric ophthalmological conditions…”
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Post-enucleation retinoblastoma: Outcome analysis and evaluation of prognostic features
Published in Journal of nature and science of medicine (01-01-2021)“…Background: The aim is to assess if International Classification for Retinoblastoma (ICRB) and American Joint Committee on Cancer Staging System (AJCC) for…”
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Histopathological assessment of optic nerve invasion guided by radiological findings in enucleated globes with retinoblastoma
Published in BMC ophthalmology (29-09-2020)“…Optic nerve (ON) invasion is an important high-risk feature, and an indicator for neoadjuvant chemotherapy and prognosis. We aim through this study to…”
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High-risk features in primary versus secondary enucleated globes with advanced retinoblastoma: a retrospective histopathological study
Published in International ophthalmology (01-11-2020)“…Purpose The management of bilateral advanced retinoblastoma (RB) cases is challenging with attempts to use neoadjuvant therapy salvaging of one of the globes…”
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Endophthalmitis post pars plana vitrectomy surgery: incidence, organisms' profile, and management outcome in a tertiary eye hospital in Saudi Arabia
Published in Middle East African journal of ophthalmology (01-01-2021)“…PURPOSE: To determine the incidence of endophthalmitis after pars plana vitrectomy (PPV), organisms' profile, and management outcomes at a tertiary eye…”
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Ocular Survival Following Intravitreal Melphalan as Adjuvant Treatment for Vitreous Retinoblastoma Seeding
Published in Clinical ophthalmology (Auckland, N.Z.) (01-01-2023)“…To evaluate the efficacy of intravitreal chemotherapy for vitreous seeding in patients with retinoblastoma (Rb). Retrospective, single-arm cohort study. This…”
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A case of retinoblastoma masquerading as endophthalmitis: Unusual presentation and clinicopathological correlation
Published in International journal of surgery case reports (01-10-2024)“…Retinoblastoma is a serious childhood intraocular neoplasm that can be diagnosed clinically with the aid of B-scan ultrasound, and radiological examination. On…”
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Clinicopathological Correlations in Enucleated Globes of Late-Stage Coats Disease with a Review of the Literature
Published in Journal of epidemiology and global health (01-12-2022)“…Coats disease may cause diagnostic dilemma because of its variable clinical presentation that can be suspicious of retinoblastoma. Late sequelae of the disease…”
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Efficacy of vincristine and carboplatin as chemo-reduction for advanced bilateral retinoblastoma, the Saudi experience
Published in Saudi journal of ophthalmology (01-07-2013)“…To evaluate the efficacy of a 2-drug chemotherapy regimen without external-beam radiotherapy (EBRT) and/or without enucleation in bilateral retinoblastoma…”
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