Search Results - "AlGhamdi, Adel"
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A detailed review of pharmacology of MFN1 (mitofusion-1)-mediated mitochondrial dynamics: Implications for cellular health and diseases
Published in Saudi pharmaceutical journal (01-04-2024)“…The mitochondria are responsible for the production of cellular ATP, the regulation of cytosolic calcium levels, and the organization of numerous apoptotic…”
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Synthesis, Molecular Docking, and Dynamic Simulation Targeting Main Protease (Mpro) of New, Thiazole Clubbed Pyridine Scaffolds as Potential COVID-19 Inhibitors
Published in Current issues in molecular biology (01-02-2023)“…Many biological activities of pyridine and thiazole derivatives have been reported, including antiviral activity and, more recently, as COVID-19 inhibitors…”
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A Case Report of a Pregnant Woman With Type 2 Diabetes Mellitus Using Dulaglutide During the First Trimester of Pregnancy
Published in Curēus (Palo Alto, CA) (04-09-2023)“…Among women of childbearing age, type 2 diabetes mellitus (T2DM) is becoming more prevalent, increasing the likelihood of abortion, congenital anomalies, and…”
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Investigating Chaperone like Activity of Green Silver Nanoparticles: Possible Implications in Drug Development
Published in Molecules (Basel, Switzerland) (29-01-2022)“…Protein aggregation and amyloidogenesis have been associated with several neurodegenerative disorders like Alzheimer's, Parkinson's etc. Unfortunately, there…”
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A Through-Life Cost Analysis Model to Support Investment Decision-Making in Concentrated Solar Power Projects
Published in Energies (Basel) (01-04-2020)“…This research paper aims to propose a through-life cost analysis model for estimating the profitability of renewable concentrated solar power (CSP)…”
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Potential Antioxidant Activity of Apigenin in the Obviating Stress-Mediated Depressive Symptoms of Experimental Mice
Published in Molecules (Basel, Switzerland) (01-12-2022)“…This study aimed to examine the antidepressant properties of apigenin in an experimental mouse model of chronic mild stress (CMS). Three weeks following CMS,…”
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Venetoclax Induces Cardiotoxicity through Modulation of Oxidative-Stress-Mediated Cardiac Inflammation and Apoptosis via NF-κB and BCL-2 Pathway
Published in International journal of molecular sciences (02-06-2022)“…Cardiovascular damage induced by anticancer therapy has become the main health problem after tumor elimination. Venetoclax (VTX) is a promising novel agent…”
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Diosmin Alleviates Doxorubicin-Induced Liver Injury via Modulation of Oxidative Stress-Mediated Hepatic Inflammation and Apoptosis via NfkB and MAPK Pathway: A Preclinical Study
Published in Antioxidants (15-12-2021)“…Hepatotoxicity caused by chemotherapeutic drugs (e.g., doxorubicin) is of critical concern in cancer therapy. This study focused on investigating the…”
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Comparative evaluation of the potential anti-spasmodic activity of Piper longum, Piper nigrum, Terminalia bellerica, Terminalia chebula, and Zingiber officinale in experimental animals
Published in Saudi pharmaceutical journal (01-09-2023)“…Spasm of muscle is one of the frequent complaints seen by most of the population worldwide. The present study evaluated the efficacy of some of the commonly…”
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Phytopharmacological Evaluation of Different Solvent Extract/Fractions From Sphaeranthus indicus L. Flowers: From Traditional Therapies to Bioactive Compounds
Published in Frontiers in pharmacology (27-10-2021)“…Sphaeranthus indicus L. is a medicinal herb having widespread traditional uses for treating common ailments. The present research work aims to explore the…”
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Neem (Azadirachta Indica) and silk fibroin associated hydrogel: Boon for wound healing treatment regimen
Published in Saudi pharmaceutical journal (01-10-2023)“…Wound healing is the complex physiological process of replacing damaged cells or tissue layers. The neem (Azadirachta Indica) has a variety of biological…”
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Insights into the SARS-CoV-2-Mediated Alteration in the Stress Granule Protein Regulatory Networks in Humans
Published in Pathogens (Basel) (11-11-2021)“…The rapidly and constantly evolving coronavirus, SARS-CoV-2, imposes a great threat to human health causing severe lung disease and significant mortality…”
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Antibiotic resistance genes prediction via whole genome sequence analysis of Stenotrophomonas maltophilia
Published in Journal of infection and public health (01-02-2024)“…Stenotrophomonas maltophilia (S. maltophilia) is the first dominant ubiquitous bacterial species identified from the genus Stenotrophomonas in 1943 from a…”
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Prevalence of Steroid-Induced Hyperglycemia in King Abdulaziz Specialist Hospital, Taif City, Saudi Arabia
Published in Curēus (Palo Alto, CA) (18-02-2024)“…Background Hyperglycemia is a common side effect of high-dose steroid therapy in hospitalized patients. Objectives To assess the prevalence of hyperglycemia…”
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Novel ibuprofen prodrug: A possible promising agent for the management of complications of Alzheimer’s disease
Published in Saudi pharmaceutical journal (01-01-2024)“…Alzheimer’s disease (AD) is a severe, varied, and complex brain condition that gradually impairs memory and cognitive function. Epidemiological studies have…”
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Neuroprotective potential of Cordia dichotoma in Parkinson's syndrome induced by haloperidol: An animal study
Published in Saudi pharmaceutical journal (01-10-2023)“…Parkinson’s disease (PD) is one of the major neurodegenerative disorders and the prevalence is expected to increaseduring the next couple of decades. There is…”
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Bridging the gap: glucose transporters, Alzheimer's, and future therapeutic prospects
Published in Frontiers in cell and developmental biology (2024)“…Glucose is the major source of chemical energy for cell functions in living organisms. The aim of this mini-review is to provide a clearer and simpler picture…”
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The efficacy of Elbasvir/Grazoprevir fixed-dose combination for 8 weeks in HCV treatment and health-related quality of life (HRQoL) in treatment-naïve, non-cirrhotic, genotype 4-infected patients (ELEGANT-4): A single-center, single-arm, open-label, phase 3 trial
Published in Saudi journal of gastroenterology (01-05-2022)“…Background: Cost, adverse events, and long treatment duration can be significant obstacles in treating hepatitis C virus (HCV)-infected individuals. Shortening…”
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Impact of Vitamin D Deficiency on Mental Health in University Students: A Cross-Sectional Study
Published in Healthcare (Basel) (01-07-2023)“…Students pursuing a university education are vulnerable to psychological burdens such as depression, anxiety, and stress. The frequency of vitamin D…”
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Molecular docking and dynamics simulation to screen interactive potency and stability of fungicide tebuconazole with thyroid and sex hormone‐binding globulin: Implications of endocrine and reproductive interruptions
Published in Journal of applied toxicology (01-10-2021)“…Tebuconazole is a widely used fungicide in agriculture, and it may easily enter in the human food chain. In addition, tebuconzaol skin permeation coefficient…”
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