Nocardia asteroides peritoneal dialysis-related peritonitis: First case in pediatrics, treated with protracted linezolid

Summary Nocardia asteroides is a rare pathogen in peritoneal dialysis-related peritonitis. We report on a 13-year-old female with Nocardia asteroides peritonitis complicated by an intra-abdominal abscess. Linezolid was administered intravenously for 3 months and followed by oral therapy for an addit...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of infection and public health Vol. 9; no. 2; pp. 192 - 197
Main Authors:	El-Naggari, Mohamed, El Nour, Ibtisam, Al-Nabhani, Dana, Al Muharrmi, Zakaria, Gaafar, Heba, Al Wogoud Abdelmogheth, Anas
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-03-2016 Elsevier
Subjects:	Abscess - diagnosis Abscess - drug therapy Abscess - microbiology Abscess - pathology Administration, Intravenous Administration, Oral Adolescent Anti-Bacterial Agents - therapeutic use Continuous ambulatory peritoneal dialysis Female Humans Infectious Disease Internal Medicine Intra-abdominal abscess Linezolid - therapeutic use Nocardia asteroides Nocardia asteroides - isolation & purification Nocardia Infections - diagnosis Nocardia Infections - drug therapy Nocardia Infections - microbiology Nocardia Infections - pathology Oman Peritoneal dialysis Peritoneal Dialysis - adverse effects Peritonitis Peritonitis - diagnosis Peritonitis - drug therapy Peritonitis - microbiology Peritonitis - pathology Treatment Outcome Nocardia asteroides Continuous ambulatory peritoneal dialysis Peritoneal dialysis Peritonitis Oman Intra-abdominal abscess
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Summary Nocardia asteroides is a rare pathogen in peritoneal dialysis-related peritonitis. We report on a 13-year-old female with Nocardia asteroides peritonitis complicated by an intra-abdominal abscess. Linezolid was administered intravenously for 3 months and followed by oral therapy for an additional 5 months with close monitoring for adverse effects. The patient was discharged after 3 months of hospitalization on hemodialysis. The diagnosis and management of such cases can be problematic due to the slow growth and difficulty of identifying Nocardia species. The optimal duration of treatment for Nocardia peritonitis is not known. Linezolid can be used for prolonged periods in cases of trimethoprim/sulfamethoxazole-resistant cases with close monitoring for adverse effects.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1876-0341 1876-035X
DOI:	10.1016/j.jiph.2015.11.003