Search Results - "Al Saif, S."

Telomerase reverse transcriptase mutations are independent predictor of disease‐free survival in Middle Eastern papillary thyroid cancer by Bu, Rong, Siraj, Abdul K., Divya, Sasidharan Padmaja, Kong, Yan, Parvathareddy, Sandeep Kumar, Al‐Rasheed, Maha, Al‐Obaisi, Khadija A.S., Victoria, Ingrid G., Al‐Sobhi, Saif S., Al‐Dawish, Mohammed, Al‐Dayel, Fouad, Al‐Kuraya, Khawla S.

“…Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Tumor recurrence occurs in ∼20% of PTCs and some reach advanced stages. Promoter…”
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PLK1 and FoxM1 expressions positively correlate in papillary thyroid carcinoma and their combined inhibition results in synergistic anti‐tumor effects by Poyil, Pratheesh Kumar, Siraj, Abdul K., Padmaja, Divya, Parvathareddy, Sandeep Kumar, Thangavel, Saravanan, Alobaisi, Khadija, Diaz, Roxanne, Begum, Rafia, Haqawi, Wael, Al‐Sobhi, Saif S., Al‐Dayel, Fouad, Al‐Kuraya, Khawla S.

“…Polo‐like kinase 1 (PLK1; also known as serine/threonine‐protein kinase PLK1) serves as a central player in cell proliferation, exerting critical regulatory…”
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Overexpression of the pro‐protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF/MEK signaling by Poyil, Pratheesh Kumar, Siraj, Abdul K., Padmaja, Divya, Parvathareddy, Sandeep Kumar, Diaz, Roxanne, Thangavel, Saravanan, Begum, Rafia, Haqawi, Wael, Al‐Mohanna, Falah Hassan, Al‐Sobhi, Saif S., Al‐Dayel, Fouad, Al‐Kuraya, Khawla S.

“…Furin belongs to the pro‐protein convertases (PCs) family and its aberrant expression has been documented in various types of cancers; however, its role in…”
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Tumor size is an independent negative prognostic factor for event free survival in children with differentiated thyroid cancer by Parvathareddy, Sandeep Kumar, Siraj, Abdul K., Annaiyappanaidu, Padmanaban, Siraj, Nabil, Haqawi, Wael, Al-Sobhi, Saif S., Al-Dayel, Fouad, Al-Kuraya, Khawla S.

“…BackgroundThe incidence of pediatric differentiated thyroid carcinoma (DTC) is increasing. Despite the advanced disease at presentation, the overall prognosis…”
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Loss of CDH16 expression is a strong independent predictor for lymph node metastasis in Middle Eastern papillary thyroid cancer by Siraj, Abdul K., Parvathareddy, Sandeep Kumar, Al-Rasheed, Maha, Annaiyappanaidu, Padmanaban, Siraj, Nabil, Lennartz, Maximilian, Al-Sobhi, Saif S., Al-Dayel, Fouad, Sauter, Guido, Al-Kuraya, Khawla S.

“…Papillary Thyroid Cancer (PTC) is the most common type of thyroid cancer. The membrane-associated glycoprotein cadherin-16 (CDH16) plays a significant role in…”
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Loss of ZNF677 Expression Is an Independent Predictor for Distant Metastasis in Middle Eastern Papillary Thyroid Carcinoma Patients by Siraj, Abdul K., Poyil, Pratheesh Kumar, Parvathareddy, Sandeep Kumar, Alobaisi, Khadija, Ahmed, Saeeda O., Al-Sobhi, Saif S., Al-Dayel, Fouad, Al-Kuraya, Khawla S.

“…Thyroid cancer incidence has increased in recent decades. Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Approximately 30% of PTC…”
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CHD4 Predicts Aggressiveness in PTC Patients and Promotes Cancer Stemness and EMT in PTC Cells by Pratheeshkumar, Poyil, Siraj, Abdul K, Divya, Sasidharan Padmaja, Parvathareddy, Sandeep Kumar, Alobaisi, Khadija, Al-Sobhi, Saif S, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Chromodomain-helicase-DNA-binding protein 4 (CHD4), a core subunit of the nucleosome remodeling and deacetylation (NuRD) complex is highly expressed in several…”
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Evaluating the Influence of Hashimoto's Thyroiditis on Clinico-Pathological Characteristics and Prognostic Outcomes of Middle Eastern Differentiated Thyroid Carcinoma by Parvathareddy, Sandeep Kumar, Siraj, Abdul K, Siraj, Nabil, Ahmed, Saeeda O, Al-Sobhi, Saif S, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Hashimoto's thyroiditis (HT), also known as chronic lymphocytic thyroiditis, represents the most prevalent autoimmune thyroid disorder globally. The potential…”
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Prognostic Significance of COX-2 Overexpression in BRAF -Mutated Middle Eastern Papillary Thyroid Carcinoma by Parvathareddy, Sandeep Kumar, Siraj, Abdul K, Annaiyappanaidu, Padmanaban, Al-Sobhi, Saif S, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…The cyclooxygenase-2 (COX-2)-prostaglandin E2 (PGE2) pathway has been implicated in carcinogenesis, with mutation shown to promote PGE2 synthesis. This study…”
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Microscopic Extrathyroidal Extension Results in Increased Rate of Tumor Recurrence and Is an Independent Predictor of Patient's Outcome in Middle Eastern Papillary Thyroid Carcinoma by Parvathareddy, Sandeep Kumar, Siraj, Abdul K, Qadri, Zeeshan, DeVera, Felisa, Siddiqui, Khawar, Al-Sobhi, Saif S, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Papillary Thyroid Cancer (PTC) is the most common endocrine malignancy, with recurrence rate as high as 30%. A great deal of controversy surrounds the…”
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Radioactive iodine refractoriness in Middle Eastern differentiated thyroid cancer: clinical outcome and risk factor analysis by Parvathareddy, Sandeep Kumar, Siraj, Abdul K, Siraj, Nabil, Ahmed, Saeeda O, Al-Rasheed, Maha, Qadri, Zeeshan, Siddiqui, Khawar, Al-Sobhi, Saif S, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Radioactive iodine refractory differentiated thyroid cancer (RAIR-DTC) has received increasing attention due to its poor prognosis. However, outcomes may vary…”
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Male Sex Is an Independent Predictor of Recurrence-Free Survival in Middle Eastern Papillary Thyroid Carcinoma by Siraj, Abdul K, Parvathareddy, Sandeep Kumar, Annaiyappanaidu, Padmanaban, Siraj, Nabil, Al-Sobhi, Saif S, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Disparity between sexes with regard to incidence, disease aggressiveness, and prognosis has been documented in several cancers. Although various reports have…”
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TERT Promoter Mutations Are an Independent Predictor of Distant Metastasis in Middle Eastern Papillary Thyroid Microcarcinoma by Parvathareddy, Sandeep Kumar, Siraj, Abdul K, Iqbal, Kaleem, Qadri, Zeeshan, Ahmed, Saeeda O, Al-Rasheed, Maha, AlQatie, Ahmed A, Al-Sobhi, Saif S, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Papillary thyroid microcarcinomas (PTMCs) have been attributed to the recent increased incidence of thyroid cancer. Although indolent, a subset of PTMC could…”
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Bilateral multifocality is an independent predictor of patients' outcome in Middle Eastern papillary thyroid carcinoma by Parvathareddy, Sandeep Kumar, Siraj, Abdul K, Annaiyappanaidu, Padmanaban, Siraj, Nabil, Al-Sobhi, Saif S, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Tumor multifocality is frequently seen in Papillary thyroid carcinoma (PTC). However, few studies have analysed the impact of bilateral multifocality in PTC…”
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Weighty Matters: The Obesity–Thyroid Nodule Connection Unveiling the Impact of Obesity on Thyroid Cancer Risk by Alqahtani, Saad M, Altalhi, Bassam A, Alalawi, Yousef S, AlFattani, Areej A, Al-Sobhi, Saif S

“…Background and Objectives: The effect of obesity on the development/progression of thyroid nodules with uncertain cytology is unknown. Therefore, our objective…”
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Risk Factors for Central Lymph Node Metastases and Benefit of Prophylactic Central Lymph Node Dissection in Middle Eastern Patients With cN0 Papillary Thyroid Carcinoma by Parvathareddy, Sandeep Kumar, Siraj, Abdul K, Ahmed, Saeeda O, DeVera, Felisa, Al-Sobhi, Saif S, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Prophylactic central lymph node dissection (PCLND) for adult patients with papillary thyroid carcinoma (PTC) is still a matter of debate. Data on incidence,…”
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Predictive risk factors for distant metastasis in pediatric differentiated thyroid cancer from Saudi Arabia by Parvathareddy, Sandeep Kumar, Siraj, Abdul K., Annaiyappanaidu, Padmanaban, Siraj, Nabil, Al-Rasheed, Maha, Al-Haqawi, Wael, Qadri, Zeeshan, Siddiqui, Khawar, Al-Sobhi, Saif S., Al-Dayel, Fouad, Al-Kuraya, Khawla S.

“…BackgroundDespite their excellent prognosis, children and young adults (CAYA) with differentiated thyroid cancer (DTC) tend to have more frequent occurrence of…”
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The common motives for appendectomy in Hail Region Saudi Arabia by Alshammari, Fawaz D, Oreiby, Hanan A, Ahmed, Hussain Gadelkarim, Alshaghdali, Khalid, Alcantara, Jerold C, Ahmed, Gamal Mohamed Elawad, Seifeldin, Sara A, Abboh, Emad Abboh Abdallah, Al Shammari, Waleed Mansi, Al Tayeeb, Fawzia Mutasim M, Al Saif, Bandar S, Al Qahtani, Ali Ahmed, Alharbi, Samir Abdulkarim, Elnaem, Ibtihag Siddig

“…Appendectomy remains the most common emergency surgery. With the lack of literature from Saudi Arabia regarding the treatment for appendix disorders, this…”
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X-linked inhibitor of apoptosis protein (XIAP) predicts disease-free survival in BRAFV600E mutant papillary thyroid carcinoma in middle eastern patients by Parvathareddy, Sandeep Kumar, Siraj, Abdul K, Bu, Rong, Iqbal, Kaleem, Al-Rasheed, Maha, Al-Haqawi, Wael, Annaiyappanaidu, Padmanaban, Siraj, Nabil, Ahmed, Saeeda O, Al-Sobhi, Saif S, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…X-linked inhibitor of apoptosis (XIAP) is the most potent caspase inhibitory IAP family member and its over-expression is implicated in aggressive behavior of…”
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Stable, efficient, and cost-effective system for the biosynthesis of recombinant bacterial cellulose in Escherichia coli DH5α platform by Al-Janabi, Saif S., Shawky, Heba, El-Waseif, Amr A., Farrag, Ayman A., Abdelghany, Tarek M., El-Ghwas, Dina E.

“…Abstract Background Owing to its remarkable mechanical properties that surpass the plant-based cellulose, bacterial cellulose production has been targeted for…”
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