Search Results - "Al Nebaihi, Hamdah"
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Piecing together human adult comparative pharmacokinetic trials and rodent studies: What happens to drug clearance in obesity?
Published in Journal of pharmacy & pharmaceutical sciences (2022)“…In many comparative trials examining the effects of adult obesity on pharmacokinetics of drugs, conclusions were made based on values that were either not…”
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A High-Performance Liquid Chromatography Assay Method for the Determination of Lidocaine in Human Serum
Published in Pharmaceutics (18-11-2017)“…Here we report on the development of a selective and sensitive high-performance liquid chromatographic method for the determination of lidocaine in human…”
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Evaluation of the pharmacokinetics, chylomicron inhibition, and toxicity of colchicine in rats given low doses
Published in European journal of pharmaceutics and biopharmaceutics (01-09-2024)“…[Display omitted] Colchicine (COL) is known for its ability to inhibit the formation of intestinal chylomicrons and has been utilized as a non-surgical tool to…”
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Pharmacokinetics of cycloheximide in rats and evaluation of its effect as a blocker of intestinal lymph formation
Published in European journal of pharmaceutics and biopharmaceutics (01-12-2023)“…Cycloheximide (CHX) has been used to reduce the flow of intestinal lymph and as a non-surgical tool to study drug absorption via the intestinal lymphatics…”
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Analysis of cycloheximide in rat specimens using liquid chromatography with tandem massspectrometry detection
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-02-2022)“…•A Method is described for the assay of cyclohexidine in rat blood fluids.•The assay was sensitive and precise.•It was capable of detecting cycloheximide in…”
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Rectus sheath single‐injection blocks: a study to quantify local anaesthetic absorption using serial ultrasound measurements and lidocaine serum concentrations
Published in Journal of pharmacy and pharmacology (01-08-2019)“…Objectives Rectus sheath blocks are an established option for analgesia following abdominal surgery, but pharmacokinetic data are limited. This study sought to…”
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Dietary-Induced Obesity and Changes in the Biodistribution and Metabolism of Amiodarone in the Rat
Published in Journal of pharmaceutical sciences (01-11-2018)“…The metabolism and biodistribution of the antiarrhythmic drug amiodarone (AM) was assessed in male Sprague-Dawley rats given either normal chow or high-fat and…”
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