Search Results - "Al Mulla, Fahd"

Preliminary Structural Data Revealed That the SARS‐CoV‐2 B.1.617 Variant's RBD Binds to ACE2 Receptor Stronger Than the Wild Type to Enhance the Infectivity by Khan, Abbas, Wei, Dong‐Qing, Kousar, Kafila, Abubaker, Jehad, Ahmad, Sajjad, Ali, Javaid, Al‐Mulla, Fahd, Ali, Syed Shujait, Nizam‐Uddin, N., Mohammad Sayaf, Abrar, Mohammad, Anwar

“…The evolution of new SARS‐CoV‐2 variants around the globe has made the COVID‐19 pandemic more worrisome, further pressuring the health care system and…”
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Neutral sphingomyelinase‐2 and cardiometabolic diseases by Sindhu, Sardar, Leung, Yat Hei, Arefanian, Hossein, Madiraju, S. R. Murthy, Al‐Mulla, Fahd, Ahmad, Rasheed, Prentki, Marc

“…Summary Sphingolipids, in particular ceramides, play vital role in pathophysiological processes linked to metabolic syndrome, with implications in the…”
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Late bedtime and dental caries incidence in Kuwaiti children: A longitudinal multilevel analysis by Alqaderi, Hend, Tavares, Mary, Al‐Mulla, Fahd, Al‐Ozairi, Ebaa, Goodson, Jo Max

“…Objective Inadequate sleep contributes to several adverse systemic health outcomes due to hormonal and metabolic disorders. The purpose of this study was to…”
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RKIP: Much more than Raf Kinase inhibitory protein by Al-Mulla, Fahd, Bitar, Milad S., Taqi, Zainab, Yeung, Kam C.

“…From its discovery as a phosphatidylethanolamine‐binding protein in bovine brain to its designation as a physiological inhibitor of Raf kinase protein, RKIP…”
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The spectrum of BRCA1 and BRCA2 pathogenic sequence variants in Middle Eastern, North African, and South European countries by Laitman, Yael, Friebel, Tara M., Yannoukakos, Drakoulis, Fostira, Florentia, Konstantopoulou, Irene, Figlioli, Gisella, Bonanni, Bernardo, Manoukian, Siranoush, Zuradelli, Monica, Tondini, Carlo, Pasini, Barbara, Peterlongo, Paolo, Plaseska‐Karanfilska, Dijana, Jakimovska, Milena, Majidzadeh, Keivan, Zarinfam, Shiva, Loizidou, Maria A., Hadjisavvas, Andreas, Michailidou, Kyriaki, Kyriacou, Kyriacos, Behar, Doron M., Molho, Rinat Bernstein, Ganz, Patricia, James, Paul, Parsons, Michael T., Sallam, Aminah, Olopade, Olufunmilayo I., Seth, Arun, Chenevix ‐ Trench, Georgia, Leslie, Goska, McGuffog, Lesley, Marafie, Makia J, Megarbane, Andre, Al‐Mulla, Fahd, Rebbeck, Timothy R., Friedman, Eitan

“…BRCA1 BRCA2 mutational spectrum in the Middle East, North Africa, and Southern Europe is not well characterized. The unique history and cultural practices…”
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Global analysis of urinary extracellular vesicle small RNAs in autosomal dominant polycystic kidney disease by Ali, Hamad, Malik, Md. Zubbair, Abu‐Farha, Mohamed, Abubaker, Jehad, Cherian, Preethi, Nizam, Rasheeba, Jacob, Sindhu, Bahbahani, Yousif, Naim, Medhat, Ahmad, Sajjad, Al‐Sayegh, Mohammad, Thanaraj, Thangavel Alphonse, Ong, Albert C. M., Harris, Peter C., Al‐Mulla, Fahd

“…Background Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent monogenic renal disease progressing to end‐stage renal disease. There is…”
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Plasma insulin is required for the increase in plasma angiopoietin‐like protein 8 in response to nutrient ingestion by Abu‐Farha, Mohamed, Alatrach, Mariam, Abubaker, Jehad, Al‐Khairi, Irina, Cherian, Preethi, Agyin, Krisitn, Abdelgani, Siham, Norton, Luke, Adams, John, Al‐Saeed, Dalal, Al‐Ozairi, Ebaa, DeFronzo, Ralph A., Al‐Mulla, Fahd, Abdul‐Ghani, Muhammad

“…Background Plasma levels of angiopoietin‐like protein 8 (ANGPTL8) are regulated by feeding and they increase following glucose ingestion. Because both plasma…”
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Urocortin Neuropeptide Levels Are Impaired in the PBMCs of Overweight Children by Kavalakatt, Sina, Khadir, Abdelkrim, Kochumon, Shihab, Madhu, Dhanya, Devarajan, Sriraman, Hammad, Maha, Alam-Eldin, Nada, Warsame, Samia, Al-Kandari, Hessa, AlMahdi, Maria, Ahmad, Rasheed, Koistinen, Heikki A, Tuomilehto, Jaakko, Al-Mulla, Fahd, Abubaker, Jehad, Tiss, Ali

“…The corticotropin-releasing hormone (CRH) and urocortins (UCNs) have been implicated in energy homeostasis and the cellular stress response. However, the…”
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ANGPTL4: A Predictive Marker for Diabetic Nephropathy by Al Attar, Abdulnabi, Abubaker, Jehad, Al-Mulla, Fahd, Ali, Hamad, Cherian, Preethi, Al-Khairi, Irina, Alsairafi, Zahra, Devarajan, Sriraman, Abu-Farha, Mohamed, Al Shawaf, Eman, Mathur, Aditi

“…Background. ANGPTL4 is a glycoprotein that is involved in regulating triglyceride metabolism by inhibiting LPL activity under fasting conditions. Additionally,…”
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Atherogenic Index of Plasma (AIP) a Tool to Assess Changes in Cardiovascular Disease Risk Post Laparoscopic Sleeve Gastrectomy by Arefanian, Hossein, Abubaker, Jehad, Devarajan, Sriraman, Al-Beloushi, Shaima, Mohammad, Anwar, Al-Asfar, Fahad, Al-Ozairi, Ebaa, Al Shawaf, Eman, Al-Mulla, Fahd

“…Predictive indices like the atherogenic index of plasma (AIP) have been developed to estimate the risk of cardiovascular disease (CVD). Metabolic surgery is…”
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Could the D614G substitution in the SARS-CoV-2 spike (S) protein be associated with higher COVID-19 mortality? by Eaaswarkhanth, Muthukrishnan, Al Madhoun, Ashraf, Al-Mulla, Fahd

“…The increasing number of deaths due to the COVID-19 pandemic has raised serious global concerns. Increased testing capacity and ample intensive care…”
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The Role of Lipid Metabolism in COVID-19 Virus Infection and as a Drug Target by Abu-Farha, Mohamed, Thanaraj, Thangavel Alphonse, Qaddoumi, Mohammad G, Hashem, Anwar, Abubaker, Jehad, Al-Mulla, Fahd

“…The current Coronavirus disease 2019 or COVID-19 pandemic has infected over two million people and resulted in the death of over one hundred thousand people at…”
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Risk of mortality among inpatients with COVID‐19 and type 2 diabetes: National data from Kuwait by Al‐Ozairi, Ebaa, Brown, Rosemary, Hamdan, Yasmine, Alabdullah, Lulwa, Voase, Nia, Al Kandari, Jumana, Alsaeed, Dalal, Al Ozairi, Abdulla, Hasan, Amal, Al‐Mulla, Fahd, Katikireddi, Srinivasa Vittal, Gray, Stuart R., Gill, Jason M. R., Celis‐Morales, Carlos A., Sattar, Naveed, Welsh, Paul

“…Introduction To investigate type 2 diabetes as a risk factor for COVID‐19 death following hospital admission in Kuwait. Methods A retrospective cohort study…”
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mTOR: Its Critical Role in Metabolic Diseases, Cancer, and the Aging Process by Marafie, Sulaiman K, Al-Mulla, Fahd, Abubaker, Jehad

“…The mammalian target of rapamycin (mTOR) is a pivotal regulator, integrating diverse environmental signals to control fundamental cellular functions, such as…”
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The Cooperative Induction of CCL4 in Human Monocytic Cells by TNF-α and Palmitate Requires MyD88 and Involves MAPK/NF-κB Signaling Pathways by Sindhu, Sardar, Kochumon, Shihab, Shenouda, Steve, Wilson, Ajit, Al-Mulla, Fahd, Ahmad, Rasheed

“…Chronic low-grade inflammation, also known as metabolic inflammation, is a hallmark of obesity and parallels with the presence of elevated circulatory levels…”
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Impact of Diabetes in Patients Diagnosed With COVID-19 by Abu-Farha, Mohamed, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse, Kavalakatt, Sina, Ali, Hamad, Abdul Ghani, Mohammed, Abubaker, Jehad

“…COVID-19 is a disease caused by the coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2), known as a highly contagious disease, currently…”
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The Two Faces of ACE2: The Role of ACE2 Receptor and Its Polymorphisms in Hypertension and COVID-19 by Bosso, Mira, Thanaraj, Thangavel Alphonse, Abu-Farha, Mohamed, Alanbaei, Muath, Abubaker, Jehad, Al-Mulla, Fahd

“…The mechanism for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection requires the binding of the virus to the angiotensin-converting enzyme…”
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Investigating the Relationship between Obstructive Sleep Apnoea, Inflammation and Cardio-Metabolic Diseases by Alterki, Abdulmohsen, Abu-Farha, Mohamed, Al Shawaf, Eman, Al-Mulla, Fahd, Abubaker, Jehad

“…Obstructive sleep apnoea (OSA) is a prevalent underdiagnosed disorder whose incidence increases with age and weight. Uniquely characterised by frequent…”
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New-Generation Glucokinase Activators: Potential Game-Changers in Type 2 Diabetes Treatment by Haddad, Dania, Dsouza, Vanessa Sybil, Al-Mulla, Fahd, Al Madhoun, Ashraf

“…Achieving glycemic control and sustaining functional pancreatic β-cell activity remains an unmet medical need in the treatment of type 2 diabetes mellitus…”
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Epidermal growth factor receptor mutations in nonsmall cell lung carcinoma patients in Kuwait by Al-Temaimi, Rabeah, Kapila, Kusum, Al-Mulla, Fahd R, Francis, Issam M, Al-Waheeb, Salah, Al-Ayadhy, Bushra

“…Nonsmall cell lung carcinoma (NSCLC) is the most frequently diagnosed form of lung cancer in Kuwait. NSCLC samples from Kuwait have never been screened for…”
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