Search Results - "Al Maskari, Raya"

The matrix proteins aggrecan and fibulin-1 play a key role in determining aortic stiffness by Yasmin, Maskari, Raya Al, McEniery, Carmel M., Cleary, Sarah E., Li, Ye, Siew, Keith, Figg, Nichola L., Khir, Ashraf W., Cockcroft, John R., Wilkinson, Ian B., O’Shaughnessy, Kevin M.

“…Stiffening of the aorta is an important independent risk factor for myocardial infarction and stroke. Yet its genetics is complex and little is known about its…”
Get full text

Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness by Maskari, Raya Al, Hardege, Iris, Cleary, Sarah, Figg, Nicki, Li, Ye, Siew, Keith, Khir, Ashraf, Yu, Yong, Liu, Pentao, Wilkinson, Ian, O'Shaughnessy, Kevin, Yasmin

“…The recent genome-wide analysis of carotid-femoral pulse wave velocity (PWV) identified a significant locus within the 14q32.2 gene desert. Gene regulatory…”
Get full text

Characterisation of the Cullin‐3 mutation that causes a severe form of familial hypertension and hyperkalaemia by Schumacher, Frances‐Rose, Siew, Keith, Zhang, Jinwei, Johnson, Clare, Wood, Nicola, Cleary, Sarah E, Al Maskari, Raya S, Ferryman, James T, Hardege, Iris, Yasmin, Figg, Nichola L, Enchev, Radoslav, Knebel, Axel, O'Shaughnessy, Kevin M, Kurz, Thimo

“…Deletion of exon 9 from Cullin‐3 (CUL3, residues 403–459: CUL3 Δ403–459 ) causes pseudohypoaldosteronism type IIE (PHA2E), a severe form of familial…”
Get full text

Targeted disruption of the Kcnj5 gene in the female mouse lowers aldosterone levels by Hardege, Iris, Long, Lu, Al Maskari, Raya, Figg, Nicola, O'Shaughnessy, Kevin M

“…Aldosterone is released from adrenal zona glomerulosa (ZG) cells and plays an important role in Na and K homoeostasis. Mutations in the human inwardly…”
Get more information

Nephroprotective effects of diminazene on doxorubicin-induced acute kidney injury in rats by Suleimani, Yousuf Al, Maskari, Raya Al, Ali, Badreldin H., Ali, Haytham, Manoj, Priyadarsini, Al-Khamiyasi, Ali, Abdelrahman, Aly M.

“…This study aimed to investigate the potential protective effects of diminazene, an activator of angiotensin II converting enzyme (ACE2), on kidney function and…”
Get full text

Nephroprotective effects of the soluble guanylyl cyclase stimulator, riociguat in doxorubicin-induced acute kidney injury in rats by Al-Maskari, Raya, Abdelrahman, Aly M., Ali, Haytham, Manoj, Priyadarsini, Al Suleimani, Yousuf

“…This study aimed to investigate the potential protective effects of riociguat, a soluble guanylyl cyclase (sGC) stimulator, on kidney function and structure in…”
Get full text

Genetic Variations on Chromosome 14 Influence BCL11B Gene Expression Levels and Aortic Stiffness by Al Maskari, Raya, Cleary, Sarah, Li, Ye, Khir, Ashraf, Mitchell, Gary, Wilkinson, Ian, O'Shaughnessy, Kevin, Yasmin

“…Abstract only…”
Get full text

A missense TGFB2 variant p.(Arg320Cys) causes a paradoxical and striking increase in aortic TGFB1/2 expression by Al Maskari, Raya, Yasmin, Cleary, S, Figg, Nikki, Mehta, Sarju, Rassl, Doris, Wilkinson, Ian, O'Shaughnessy, Kevin M

“…Loeys-Dietz syndrome (LDS) is an autosomal dominant connective tissue disorder with a range of cardiovascular, skeletal, craniofacial and cutaneous…”
Get full text