Search Results - "Al Madhoun, A"

Injected matrix stimulates myogenesis and regeneration of mouse skeletal muscle after ischaemic injury by Kuraitis, D, Ebadi, D, Zhang, P, Rizzuto, E, Vulesevic, B, Padavan, D T, Al Madhoun, A, McEwan, K A, Sofrenovic, T, Nicholson, K, Whitman, S C, Mesana, T G, Skerjanc, I S, Musarò, A, Ruel, M, Suuronen, E J

“…Biomaterial-guided regeneration represents a novel approach for the treatment of myopathies. Revascularisation and the intramuscular extracellular matrix are…”
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24-LB: Guanfacine Normalizes Presynaptic Alpha-2 Adrenoceptors Enrichment and Ameliorates Neuropathic Pain in Type 1 Diabetic Rats by MUNAWAR, NEHA, AL MADHOUN, ASHRAF, NADER, JOELLE, AL-ALI, WALEED, MASOCHA, WILLIAS, AL-MULLA, FAHD, BITAR, MILAD S.

“…Diabetes is associated with several complications, including neuropathic pain, which is challenging to manage with currently available drugs. Descending…”
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196 Injectable matrix activates myogenic differentiation in embryonic stem cells and regenerates muscle in ischemic tissue by Kuraitis, D, Ebadi, D, Zhang, P, Vulesevic, B, Al-Madhoun, A, Sofrenovic, T, Mesana, T.G, Skerjanc, I, Ruel, M, Suuronen, E.J

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Temporal distribution of non-methane hydrocarbon (NMHC) in a developing equatorial island by Al Madhoun, Wesam A., Ramli, Nor Azam, Yahaya, Ahmad Shukri, Rashid, M.

“…Non-methane hydrocarbons (NMHC) play a vital role in the formation of ozone in urban environment, where vehicle emissions are dominant. Ozone is known for its…”
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The role of thymidine kinases in the activation of pyrimidine nucleoside analogues by Al-Madhoun, Ashraf S, Tjarks, Werner, Eriksson, Staffan

“…Deoxynucleoside analogues need activation by deoxynucleoside kinases to serve as antiviral or anticancer agents. Here we review the properties of cellular…”
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Synthesis and Biological Evaluation of Neutral and Zwitterionic 3-Carboranyl Thymidine Analogues for Boron Neutron Capture Therapy by Byun, Youngjoo, Yan, Junhua, Al-Madhoun, Ashraf S, Johnsamuel, Jayaseharan, Yang, Weilian, Barth, Rolf F, Eriksson, Staffan, Tjarks, Werner

“…Novel 3-carboranyl thymidine analogues (3CTAs) were synthesized as potential boron delivery agents for boron neutron capture therapy (BNCT). This library…”
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The synthesis and biochemical evaluation of thymidine analogues substituted with nido carborane at the N-3 position by Byun, Youngjoo, Yan, Junhua, Al-Madhoun, Ashraf S, Johnsamuel, Jayaseharan, Yang, Weilian, Barth, Rolf F, Eriksson, Staffan, Tjarks, Werner

“…Several thymidine analogues substituted with closo- and nido-carborane at the N-3 position were synthesized. The nido-carboranyl thymidine analogues were…”
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Synthesis of a Small Library of 3-(Carboranylalkyl)thymidines and Their Biological Evaluation as Substrates for Human Thymidine Kinases 1 and 2 by Al-Madhoun, Ashraf S, Johnsamuel, Jayaseharan, Yan, Junhua, Ji, Weihua, Wang, Jianghai, Zhuo, Jin-Cong, Lunato, Anthony J, Woollard, Jeffrey E, Hawk, Andrew E, Cosquer, Guirec Y, Blue, Thomas E, Eriksson, Staffan, Tjarks, Werner

“…A small library consisting of two series of thymidine derivatives containing o-carboranylalkyl groups at the N-3 position was prepared. In both series, alkyl…”
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Short Sleep Duration and Its Association with Obesity and Other Metabolic Risk Factors in Kuwaiti Urban Adults by Al-Rashed, Fatema, Sindhu, Sardar, Al Madhoun, Ashraf, Alghaith, Abdulwahab, Azim, Rafaat, Al-Mulla, Fahd, Ahmad, Rasheed

“…Background: Efficient sleep duration and its quality are increasingly recognized as important contributors for maintaining normal body weight. However,…”
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IFN-γ and LPS Induce Synergistic Expression of CCL2 in Monocytic Cells via H3K27 Acetylation by Akhter, Nadeem, Kochumon, Shihab, Hasan, Amal, Wilson, Ajit, Nizam, Rasheeba, Al Madhoun, Ashraf, Al-Rashed, Fatema, Arefanian, Hossein, Alzaid, Fawaz, Sindhu, Sardar, Al-Mulla, Fahd, Ahmad, Rasheed

“…Background: Overexpression of CCL2 (MCP-1) has been implicated in pathogenesis of metabolic conditions, such as obesity and T2D. However, the mechanisms…”
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Expression of ascorbate oxidase isoenzymes in cucurbits and during development and ripening of melon fruit by Al-Madhoun, Ashraf S., Sanmartin, Maite, Kanellis, Angelos K.

“…At least 14 ascorbate oxidase (AO) isoenzymes with isoelectric points in the range of pH 3–10 have been identified and their expression profile studied in…”
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Ketogenic diet attenuates cerebellar atrophy progression in a subject with a biallelic variant at the ATAD3A locus by Al Madhoun, Ashraf, Alnaser, Fahad, Melhem, Motasem, Nizam, Rasheeba, Al-Dabbous, Tala, Al-Mulla, Fahd

“…The ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural…”
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Phosphorylation of Isocarbostyril- and Difluorophenyl-Nucleoside Thymidine Mimics by the Human Deoxynucleoside Kinases by Al-Madhoun, Ashraf Said, Eriksson, Staffan, Wang, Zhi-Xian, Naimi, Ebrahim, Knaus, Edward E., Wiebe, Leonard I.

“…The thymidine mimics isocarbostyril nucleosides and difluorophenyl nucleosides were tested as deoxynucleoside kinase substrates using recombinant human…”
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Mitochondrial DNA D-loop sequencing reveals obesity variants in an Arab population by Eaaswarkhanth, Muthukrishnan, Melhem, Motasem, Sharma, Prem, Nizam, Rasheeba, Al Madhoun, Ashraf, Chaubey, Gyaneshwer, Alsmadi, Osama, AlOzairi, Ebaa, Al-Mulla, Fahd

“…The association of mitochondrial DNA (mtDNA) variations with obesity has been investigated in diverse populations across the world. However, such…”
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Ketogenic diet attenuates cerebellar atrophy progression in a subject with a biallelic variant at the ATAD3A locus [Response to Letter] by Al Madhoun, Ashraf, Alnaser, Fahad, Melhem, Motasem, Nizam, Rasheeba, Al-Dabbous, Tala, Al-Mulla, Fahd

“…Ashraf Al Madhoun,1,2 Fahad Alnaser,3 Motasem Melhem,1 Rasheeba Nizam,1 Tala Al-Dabbous,4 Fahd Al-Mulla11Genetics and Bioinformatics Department, Dasman…”
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1278-P: The Tale of Caveolin 1 rs1997623 Variant in Obesity and Metabolic Syndrome by MADHOUN, ASHRAF AL, HADDAD, DANIA, KOCHUMON, SHIHAB P., NIZAM, RASHEEBA, JACOB, SINDHU, SINDHU, SARDAR T., AHMAD, RASHEED, ALMULLA, FAHD

“…We Have previously established that caveolin-1 (CAV1) rs1997623 C/A variant is associated with metabolic syndrome in obese children (PMID: 30622557) and adults…”
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75-OR: IL-6R (Trans Signaling) Is a Major Modulator of Reverse Cholesterol Transport in Lipid-Laden Macrophages by ALRASHED, FATEMA, ALZAQQAH, FATEMAH, MADHOUN, ASHRAF AL, ALQABANDI, RAWAN, SINDHU, SARDAR T., ALMULLA, FAHD, AHMAD, RASHEED

“…The onset of obesity is vastly associated with low levels of high-density lipoprotein cholesterol (HDL-C) , which predisposes to cardiovascular diseases…”
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1718-P: Type 2 Diabetes Is Associated with Higher Serum Levels of Circulating Adenylyl Cyclase 8: A Novel Biomarker of the Disease by MADHOUN, ASHRAF AL, AL-MULLA, FAHD

“…Aim: A prospective study to evaluate the functional relevance of circulating adenylyl cyclase’s (ADCY), specifically ADCY1, 3 and 8 in patients with type 2…”
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1609-P: Neutral Sphingomyelinase Inhibition Limits Hepatic-Lipotoxicity and Inflammation in a Cell Model of Steatosis by ALRASHED, FATEMA, AREFANIAN, HOSSEIN, SINDHU, SARDAR T., BAHMAN, FATEMAH, ALSAEED, HALEMAH, AL MADHOUN, ASHRAF, ALZAID, FAWAZ, AL-MULLA, FAHD, AHMAD, RASHEED

“…Nonalcoholic fatty liver disease (NAFLD) represents a global healthcare challenge; it is the hepatic manifestation of metabolic syndrome and is strongly…”
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1690-P: Adipose Tissue Dectin-1 Upregulation in Hyperglycemic Obesity Involves TNF-α/NF-kB Mediated Signaling by AL MADHOUN, ASHRAF, HADDAD, DANIA, KOCHUMON, SHIHAB P., ALRASHED, FATEMA, THOMAS, REEBY S., MIRANDA, LAVINA P., SINDHU, SARDAR T.A.K., AHMAD, RASHEED, ALMULLA, FAHD

“…Dectin-1 is a pathogen recognition receptor as well as an innate immune response modulator; its function in metabolic disorders is yet unclear. Previously, we…”
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