Search Results - "Al Khairi, Irina"

Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes by Qaddoumi, Mohammad G., Alanbaei, Muath, Hammad, Maha M., Al Khairi, Irina, Cherian, Preethi, Channanath, Arshad, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd, Abu-Farha, Mohamed, Abubaker, Jehad

“…Myeloperoxidase (MPO) is positively associated with obesity and diet-induced insulin resistance. Angiopoietin-like protein 6 (ANGPTL6) regulates metabolic…”
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Plasma insulin is required for the increase in plasma angiopoietin‐like protein 8 in response to nutrient ingestion by Abu‐Farha, Mohamed, Alatrach, Mariam, Abubaker, Jehad, Al‐Khairi, Irina, Cherian, Preethi, Agyin, Krisitn, Abdelgani, Siham, Norton, Luke, Adams, John, Al‐Saeed, Dalal, Al‐Ozairi, Ebaa, DeFronzo, Ralph A., Al‐Mulla, Fahd, Abdul‐Ghani, Muhammad

“…Background Plasma levels of angiopoietin‐like protein 8 (ANGPTL8) are regulated by feeding and they increase following glucose ingestion. Because both plasma…”
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ANGPTL4: A Predictive Marker for Diabetic Nephropathy by Al Attar, Abdulnabi, Abubaker, Jehad, Al-Mulla, Fahd, Ali, Hamad, Cherian, Preethi, Al-Khairi, Irina, Alsairafi, Zahra, Devarajan, Sriraman, Abu-Farha, Mohamed, Al Shawaf, Eman, Mathur, Aditi

“…Background. ANGPTL4 is a glycoprotein that is involved in regulating triglyceride metabolism by inhibiting LPL activity under fasting conditions. Additionally,…”
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Physical Exercise Reduces the Expression of RANTES and Its CCR5 Receptor in the Adipose Tissue of Obese Humans by Elkum, Naser, Hammad, Maha, Kavalakatt, Sina, Lehe, Cynthia, Warsame, Samia, Behbehani, Kazem, Dermime, Said, Dehbi, Mohammed, Cherian, Preethi, Al-Khairi, Irina, Al-Ghimlas, Fahad, Khadir, Abdelkrim, Abu-Farha, Mohamed, Tiss, Ali, Abubaker, Jehad, Baturcam, Engin, John, Jeena

“…RANTES and its CCR5 receptor trigger inflammation and its progression to insulin resistance in obese. In the present study, we investigated for the first time…”
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Changes in the expression of meteorin‐like (METRNL), irisin (FNDC5), and uncoupling proteins (UCPs) after bariatric surgery by Jamal, Mohammad H., AlOtaibi, Fatemah, Dsouza, Carol, Al‐Sabah, Suleiman, Al‐Khaledi, Ghanim, Al‐Ali, Waleed, Ali, Hamad, Cherian, Preethi, Al‐Khairi, Irina, Devarajan, Sriraman, Abu‐Farha, Mohamed, Al‐Mulla, Fahd, Abubaker, Jehad

“…Abtract Objective Bariatric surgery is currently the most effective treatment for severe obesity. This study aims to investigate the changes in expression…”
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Investigating the Role of FABP4 in Diabetes and Obesity and the Influence of Age and Ethnicity: A Comprehensive Analysis of a Cohort from the KEDP-Study by Abdalla, Mohammed A, Abubaker, Jehad, Abu-Farha, Mohamed, Al-Khairi, Irina, Cherian, Preethi, Qaddoumi, Mohammad G, Al-Rashed, Fatema, Thanaraj, Thangavel Alphonse, Albatineh, Ahmed N, Al-Mulla, Fahd

“…Adipocyte P2 (aP2), also known as FABP4, is an adipokine that adipose tissue produces and expresses in macrophages. Its primary role is to facilitate the…”
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211-OR: Plasma Insulin Is Required for the Increase in Plasma ANGPTL8 Concentration following Glucose Ingestion by ABU-FARHA, MOHAMED, ABUBAKER, JEHAD, KHAIRI, IRINA AL, CHERIAN, PREETHI T., AGYIN, CHRISTINA, ABDELGANI, SIHAM, ALOZAIRI, EBAA S., ADAMS, JOHN M., ALMULLA, FAHD, DEFRONZO, RALPH A., ABDUL-GHANI, MUHAMMAD

“…Aim: ANGPTL8 plays an important role in regulating lipoprotein lipase activity. Its plasma level is increased following nutrient ingestion. Its not well…”
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Increased ANGPTL3, 4 and ANGPTL8/betatrophin expression levels in obesity and T2D by Abu-Farha, Mohamed, Al-Khairi, Irina, Cherian, Preethi, Chandy, Betty, Sriraman, Devarajan, Alhubail, Asma, Al-Refaei, Faisal, AlTerki, Abdulmohsen, Abubaker, Jehad

“…Hypertriglyceridemia is associated with increased risk for cardiovascular diseases and type 2 diabetes (T2D). Angiopoietin like proteins particularly 3, 4 and…”
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Increased Levels of Circulating IGFBP4 and ANGPTL8 with a Prospective Role in Diabetic Nephropathy by AlMajed, Hana Th, Abu-Farha, Mohamed, Alshawaf, Eman, Devarajan, Sriraman, Alsairafi, Zahra, Elhelaly, Ashraf, Cherian, Preethi, Al-Khairi, Irina, Ali, Hamad, Jose, Rose Mol, Thanaraj, Thangavel Alphonse, Al-Ozairi, Ebaa, Al-Mulla, Fahd, Al Attar, Abdulnabi, Abubaker, Jehad

“…Diabetic nephropathy (DN) is a complicated condition related to type 2 diabetes mellitus (T2D). ANGPTL8 is a hepatic protein highlighted as a risk factor for…”
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Proteomics analysis of human obesity reveals the epigenetic factor HDAC4 as a potential target for obesity by Abu-Farha, Mohamed, Tiss, Ali, Abubaker, Jehad, Khadir, Abdelkrim, Al-Ghimlas, Fahad, Al-Khairi, Irina, Baturcam, Engin, Cherian, Preethi, Elkum, Naser, Hammad, Maha, John, Jeena, Kavalakatt, Sina, Warsame, Samia, Behbehani, Kazem, Dermime, Said, Dehbi, Mohammed

“…Sedentary lifestyle and excessive energy intake are prominent contributors to obesity; a major risk factors for the development of insulin resistance, type 2…”
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Early autoantibody screening for type 1 diabetes: a Kuwaiti perspective on the advantages of multiplexing chemiluminescent assays by Al-Mulla, Fahd, Alhomaidah, Doha, Abu-Farha, Mohamed, Hasan, Amal, Al-Khairi, Irina, Nizam, Rasheeba, Alqabandi, Rawan, Alkandari, Hessa, Abubaker, Jehad

“…Type 1 diabetes (T1D) incidence has increased globally over the last decades, alongside other autoimmune diseases. Early screening of individuals at risk of…”
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Plasma and adipose tissue level of angiopoietin-like 7 (ANGPTL7) are increased in obesity and reduced after physical exercise by Abu-Farha, Mohamed, Cherian, Preethi, Al-Khairi, Irina, Madhu, Dhanya, Tiss, Ali, Warsam, Samia, Alhubail, Asma, Sriraman, Devarajan, Al-Refaei, Faisal, Abubaker, Jehad

“…ANGPTL7 is a member of the Angiopoietin-like (ANGPTL) protein family that is composed of eight proteins (1-8). Increasing evidence is associating ANGPTL…”
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Evaluating the correlation of sclerostin levels with obesity and type 2 diabetes in a multiethnic population living in Kuwait by Alramah, Tahani, Cherian, Preethi, Al-Khairi, Irina, Abu-Farha, Mohamed, Thanaraj, Thangavel Alphonse, Albatineh, Ahmed N, Safadi, Fayez, Ali, Hamad, Abdul-Ghani, Muhammad, Tuomilehto, Jaakko, Koistinen, Heikki A, Al-Mulla, Fahd, Abubaker, Jehad

“…Obesity and Type 2 Diabetes Mellitus (T2DM) are intricate metabolic disorders with a multifactorial etiology, often leading to a spectrum of complications…”
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Association Between Factors Involved in Bone Remodeling (Osteoactivin and OPG) With Plasma Levels of Irisin and Meteorin-Like Protein in People With T2D and Obesity by Cherian, Preethi, Al-Khairi, Irina, Jamal, Mohammad, Al-Sabah, Suleiman, Ali, Hamad, Dsouza, Carol, Alshawaf, Eman, Al-Ali, Waleed, Al-Khaledi, Ghanim, Al-Mulla, Fahd, Abu-Farha, Mohamed, Abubaker, Jehad

“…The musculoskeletal system consisting of bones and muscles have been recognized as endocrine organs secreting hormones that are involved in regulating…”
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Effect of pioglitazone on inflammatory response and clinical outcome in T2DM patients with COVID-19: a randomized multicenter double-blind clinical trial by Baagar, Khaled, Alessa, Thamer, Abu-Farha, Mohamed, Abubaker, Jehad, Alhumaidi, Heba, Franco Ceruto, Jose Antonio, Hamad, Mohammad Khair, Omrani, Ali, Abdelrahman, Salma, Zaka-Ul Haq, Muhammad, Safi, Abdul Wajid, Alhariri, Bassem, Barman, Manish, Abdelmajid, Alaaeldin, Cancio, Humberto Vidal Denis, Elmekaty, Eman, Al-Khairi, Irina, Cherian, Preethi, Jayyousi, Lina, Ahmed, Mohammed, Qaddoumi, Mohammed, Hajji, Sulaiman, Esmaeel, Ahmad, Al-Andaleeb, Ali, Channanath, Arshad, Devarajan, Sriraman, Ali, Hamad, Thanaraj, Thangavel Alphonse, Al-Sabah, Salman, Al-Mulla, Fahd, Abdul-Ghani, Muhammad, Jayyousi, Amin

“…Coronavirus disease 2019 (COVID-19) caused by the coronavirus SARS-CoV-2, has emerged as a rapidly spreading contagious disease across the globe. Recent…”
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MAP kinase phosphatase DUSP1 is overexpressed in obese humans and modulated by physical exercise by Khadir, Abdelkrim, Tiss, Ali, Abubaker, Jehad, Abu-Farha, Mohamed, Al-Khairi, Irina, Cherian, Preethi, John, Jeena, Kavalakatt, Sina, Warsame, Samia, Al-Madhoun, Ashraf, Al-Ghimlas, Fahad, Elkum, Naser, Behbehani, Kazem, Dermime, Said, Dehbi, Mohammed

“…Chronic low-grade inflammation and dysregulation of the stress defense system are cardinal features of obesity, a major risk factor for the development of…”
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Adolescent obesity and ANGPTL8: correlations with high sensitivity C-reactive protein, leptin, and chemerin by Hammad, Maha M, Channanath, Arshad M, Abu-Farha, Mohamed, Rahman, Abdur, Al Khairi, Irina, Cherian, Preethi, Alramah, Tahani, Alam-Eldin, Nada, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse, Abubaker, Jehad

“…Angiopoietin-like proteins (ANGPTLs) mediate many metabolic functions. We had recently reported increased plasma levels of ANGPTL8 in obese adults of Arab…”
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Association of significantly elevated plasma levels of NGAL and IGFBP4 in patients with diabetic nephropathy by Ali, Hamad, Abu-Farha, Mohamed, Alshawaf, Eman, Devarajan, Sriraman, Bahbahani, Yousif, Al-Khairi, Irina, Cherian, Preethi, Alsairafi, Zahra, Vijayan, Vidya, Al-Mulla, Fahd, Al Attar, Abdulnabi, Abubaker, Jehad

“…Diabetic nephropathy (DN) is a type of progressive kidney disease affecting approximately 40% of patients with diabetes. Current DN diagnostic criteria…”
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DNAJB3/HSP-40 cochaperone is downregulated in obese humans and is restored by physical exercise by Abubaker, Jehad, Tiss, Ali, Abu-Farha, Mohamed, Al-Ghimlas, Fahad, Al-Khairi, Irina, Baturcam, Engin, Cherian, Preethi, Elkum, Naser, Hammad, Maha, John, Jeena, Kavalakatt, Sina, Khadir, Abdelkrim, Warsame, Samia, Dermime, Said, Behbehani, Kazem, Dehbi, Mohammed

“…Obesity is a major risk factor for a myriad of disorders such as insulin resistance and diabetes. The mechanisms underlying these chronic conditions are…”
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Increased expression level of ANGPTL8 in white adipose tissue under acute and chronic cold treatment by Arefanian, Hossein, Al-Khairi, Irina, Khalaf, Nermeen Abu, Cherian, Preethi, Kavalakatt, Sina, Madhu, Dhanya, Mathur, Aditi, Qaddoumi, Mohamed G, Al-Mulla, Fahd, Abubaker, Jehad, Abu-Farha, Mohamed

“…Angiopoietin-like proteins (ANGPTL), primarily 3, 4, and 8, play a major role in maintaining energy homeostasis by regulating triglyceride metabolism. This…”
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