Search Results - "Al Khabbaz, Hana J."
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Repositioning Linagliptin for the Mitigation of Cadmium-Induced Testicular Dysfunction in Rats: Targeting HMGB1/TLR4/NLRP3 Axis and Autophagy
Published in Pharmaceuticals (Basel, Switzerland) (11-07-2022)“…Cadmium, a ubiquitous environmental toxicant, disrupts testicular function and fertility. The dipeptidyl peptidase-4 inhibitor linagliptin has shown pronounced…”
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Journal Article -
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Targeting oxidative stress, apoptosis, and autophagy by galangin mitigates cadmium-induced renal damage: Role of SIRT1/Nrf2 and AMPK/mTOR pathways
Published in Life sciences (1973) (15-02-2022)“…Galangin, a bioactive flavonoid with remarkable antioxidant and anti-apoptotic actions, has demonstrated promising amelioration of experimental hepatotoxicity,…”
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Journal Article -
3
Perindopril/Ambrosin Combination Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice: Crosstalk between Toll-Like Receptor 4, the Pro-Inflammatory Pathways, and SIRT1/PPAR-γ Signaling
Published in Pharmaceuticals (Basel, Switzerland) (13-05-2022)“…Colitis is one of the inflammatory states that affect the intestinal wall and may even predispose to malignancy due to chronic irritation. Although the…”
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Journal Article -
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Targeting inflammation and redox perturbations by lisinopril mitigates Freund’s adjuvant-induced arthritis in rats: role of JAK-2/STAT-3/RANKL axis, MMPs, and VEGF
Published in Inflammopharmacology (01-10-2022)“…Background Cardiovascular disorders are major complications of rheumatoid arthritis (RA). Hence, finding effective agents that can target RA progression and…”
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Journal Article -
5
Prevalence of HLA-B27 in the general population and in patients with axial spondyloarthritis in Saudi Arabia
Published in Clinical rheumatology (01-07-2017)“…The prevalence of HLA-B27 in the general population and in axial spondyloarthritis (axSpA) patients in Saudi Arabia is unknown. The aim of this study was to…”
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Journal Article -
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Pharmacovigilance in Saudi Arabia: A Narrative Review on Adverse Drug Reaction Reporting
Published in International journal of research in pharmaceutical sciences (17-10-2023)“…Adverse drug reaction (ADR) reporting is an important aspect of pharmacovigilance (PV) in ensuring drug safety during the post-marketing surveillance phase…”
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Journal Article -
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The role of the Neonatal Fc Receptor (FcRn) in the transfer of passive immunity and maintenance of active autoimmunity
Published 01-01-2008“…The Neonatal Fc Receptor (FcRn) is a unique receptor that belongs to the Major Histocompatibility Complex (MHC) protein family and was first isolated from the…”
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Dissertation -
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The role of the Neonatal Fc Receptor (FcRn) in the transfer of passive immunity and maintenance of active autoimmunity
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Dissertation