Search Results - "Al Kassem, Hatem"

Soluble Urokinase Plasminogen Activator Receptor Level Is an Independent Predictor of the Presence and Severity of Coronary Artery Disease and of Future Adverse Events by Eapen, Danny J., Manocha, Pankaj, Ghasemzadeh, Nima, Patel, Riyaz S., Al Kassem, Hatem, Hammadah, Muhammad, Veledar, Emir, Le, Ngoc‐Anh, Pielak, Tomasz, Thorball, Christian W., Velegraki, Aristea, Kremastinos, Dimitrios T., Lerakis, Stamatios, Sperling, Laurence, Quyyumi, Arshed A.

“…Introduction Soluble urokinase plasminogen activator receptor (suPAR) is an emerging inflammatory and immune biomarker. Whether suPAR level predicts the…”
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Coronary heart disease alters intercellular communication by modifying microparticle-mediated microRNA transport by Finn, Nnenna A., Eapen, Danny, Manocha, Pankaj, Al Kassem, Hatem, Lassegue, Bernard, Ghasemzadeh, Nima, Quyyumi, Arshed, Searles, Charles D.

“…•The circulating miRNA transport profile is altered in coronary heart disease (CHD) patients.•CHD is associated with decreased miRNA loading of microparticles…”
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Elevated Levels of Serum Fibrin and Fibrinogen Degradation Products Are Independent Predictors of Larger Coronary Plaques and Greater Plaque Necrotic Core by Corban, Michel T, Hung, Olivia Y, Mekonnen, Girum, Eshtehardi, Parham, Eapen, Danny J, Rasoul-Arzrumly, Emad, Kassem, Hatem Al, Manocha, Pankaj, Ko, Yi-An, Sperling, Laurence S, Quyyumi, Arshed A, Samady, Habib

“…Background:Co-existence of vulnerable plaque and pro-thrombotic state may provoke acute coronary events. It was hypothesized that elevated serum levels of…”
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Oxidative Stress Is Associated With Increased Pulmonary Artery Systolic Pressure in Humans by GHASEMZADEH, Nima, PATEL, Riyaz S, QUYYUMI, Arshed A, EAPEN, Danny J, VELEDAR, Emir, HATEM AL KASSEM, MANOCHA, Pankaj, KHAYATA, Mohamed, MAZIAR ZAFARI, A, SPERLING, Laurence, JONES, Dean P

“…Oxidative stress contributes to the development of pulmonary hypertension in experimental models, but this association in humans is unknown. We investigated…”
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Circulating CD34+ Progenitor Cells and Risk of Mortality in a Population With Coronary Artery Disease by Patel, Riyaz S, Li, Qunna, Ghasemzadeh, Nima, Eapen, Danny J, Moss, Lauren D, Janjua, A Umair, Manocha, Pankaj, Al Kassem, Hatem, Veledar, Emir, Samady, Habib, Taylor, W Robert, Zafari, A Maziar, Sperling, Laurence, Vaccarino, Viola, Waller, Edmund K, Quyyumi, Arshed A

“…RATIONALE:Low circulating progenitor cell numbers and activity may reflect impaired intrinsic regenerative/reparative potential, but it remains uncertain…”
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Pathway-Specific Aggregate Biomarker Risk Score Is Associated With Burden of Coronary Artery Disease and Predicts Near-Term Risk of Myocardial Infarction and Death by Ghasemzedah, Nima, Hayek, Salim S, Ko, Yi-An, Eapen, Danny J, Patel, Riyaz S, Manocha, Pankaj, Al Kassem, Hatem, Khayata, Mohamed, Veledar, Emir, Kremastinos, Dimitrios, Thorball, Christian W, Pielak, Tomasz, Sikora, Sergey, Zafari, A Maziar, Lerakis, Stamatios, Sperling, Laurence, Vaccarino, Viola, Epstein, Stephen E, Quyyumi, Arshed A

“…Inflammation, coagulation, and cell stress contribute to atherosclerosis and its adverse events. A biomarker risk score (BRS) based on the circulating levels…”
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Abstract 14862: Electrophysiological Predictors of Susceptible Atrial Substrate for the Onset and Recurrence of Atrial Fibrillation by Mayer, Michael, Aziz, Zaid, Deshmukh, Amrish, Al Kassem, Hatem, Beaser, Andrew, Upadhyay, Gaurav A, Emami, Maryam, Ozcan, Cevher

“…Abstract only Introduction: Atrial electro-anatomical substrate is essential for pathogenesis of atrial fibrillation (AF). Electrophysiological markers of AF…”
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Plasma soluble urokinase-type plasminogen activator receptor level is independently associated with coronary microvascular function in patients with non-obstructive coronary artery disease by Mekonnen, Girum, Corban, Michel T, Hung, Olivia Y, Eshtehardi, Parham, Eapen, Danny J, Al-Kassem, Hatem, Rasoul-Arzrumly, Emad, Gogas, Bill D, McDaniel, Michael C, Pielak, Tomasz, Thorball, Christian W, Sperling, Laurence, Quyyumi, Arshed A, Samady, Habib

“…Abstract Background : Soluble urokinase-type plasminogen activator receptor (suPAR) is a novel biomarker released from leukocytes and endothelial cells that…”
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Plasma stromal cell-derived factor 1α/CXCL12 level predicts long-term adverse cardiovascular outcomes in patients with coronary artery disease by Ghasemzadeh, Nima, Hritani, Abdul Wahab, De Staercke, Christine, Eapen, Danny J, Veledar, Emir, Al Kassem, Hatem, Khayata, Mohamed, Zafari, A.Maziar, Sperling, Laurence, Hooper, Craig, Vaccarino, Viola, Mavromatis, Kreton, Quyyumi, Arshed A

“…Abstract Objective : Stromal derived factor-1α/CXCL12 is a chemoattractant responsible for homing of progenitor cells to ischemic tissues. We aimed to…”
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A DISTINCT PERIPHERAL BLOOD GENE EXPRESSION PROFILE IS ASSOCIATED WITH ACUTE MYOCARDIAL INFARCTION AND PREDICTS RISK OF CARDIOVASCULAR DEATH by Ghasemzadeh, Nima, Kim, Jinhee, Eapen, Danny, Kassem, Hatem Al, Manocha, Pankaj, Khayata, Mohamed, Arafat, Dalia, Patel, Riyaz, Kumar, Saket, Sperling, Laurence, Gibson, Greg, Quyyumi, Arshed

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Abstract 17584: Pulmonary Artery Systolic Pressure Independently Predicts All-Cause Mortality in Patients with Coronary Artery Disease Irrespective of a Diagnosis of Heart Failure by Ghasemzadeh, Nima, Alanbari, Raghda, Hayek, Salim, Awad, Mosab, Khayata, Mohamed, Alzaraneh, Bushra, Al Kassem, Hatem, Smith, Graham, Kumar, Saket, Saon, Md, Zheng, Shuai, Yadalam, Adithya K, Dhammaputri, Christella, Tabba, Aisha, Butler, Javed, Sperling, Laurence S, Quyyumi, Arshed A

“…Abstract only Background: Elevated pulmonary artery systolic pressure (PASP) is associated with a worse outcome in heart failure (HF), but the prognostic role…”
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Abstract 11661: A Family History of Premature Coronary Artery Disease is Associated With Location and Severity of Angiographically Defined Coronary Artery Stenosis by Hammadah, Muhammad, Patel, Riyaz S, Eapen, Danny J, Samman Tahhan, Ayman, Ghasemzadeh, Nima, Al Kassem, Hatem, Khayata, Mohamed, Manocha, Pankaj, Awad, Mosaab, Kassas, Ibrahim, Alkhoder, Ayman, Veledar, Emir, Quyyumi, Arshed A

“…Abstract only Introduction: A family history (FH) of premature coronary artery disease (CAD) is an important prognostic risk factor. Emerging evidence suggests…”
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Abstract 18350: A Composite Risk Score of Biomarkers of Inflammation, Thrombosis, and Cell Stress Pathways Significantly Predict Risk of Adverse Cardiovascular Outcomes by Ghasemzadeh, Nima, Al Kassem, Hatem, Eapen, Danny, Khayata, Mohamed, Tahhan, Ayman S, Manocha, Pankaj, Alzaraneh, Bushra, Nanjundappa, Ravi, Thorball, Chrsitian W, Patel, Riyaz, Lerakis, Stamatios, Sperling, Laurence, Pielak, Tomasz, Sikora, Sergey, Epstein, Stephen E, Quyyumi, Arshed A

“…Abstract only Background: An aggregate biomarker risk score of C-reactive protein (CRP), heat shock protein (HSP)-70, and fibrin degradation products (FDP)…”
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ELEVATED LEVELS OF FIBRIN DEGRADATION PRODUCTS IS AN INDEPENDENT PREDICTOR OF INTRAVASCULAR ULTRASOUND–DEFINED FEATURES OF PLAQUE VULNERABILITY IN PATIENTS WITH CORONARY ARTERY DISEASE by Toni Corban, Michel, Eshtehardi, Parham, Eapen, Danny, Rasoul–Arzrumly, Emad, Kassem, Hatem Al, Manocha, Pankaj, Patel, Aalok, Sikora, Sergey, Mekonnen, Girum, Hassanyar, Mohammad Reza, Sperling, Laurence, Quyyumi, Arshed, Samady, Habib

“…In a multivariate regression analysis, after adjustment for age, sex, tobacco abuse, hypertension, diabetes, body mass index, dyslipidemia and ACS, age…”
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Abstract 18729: Serum Heat Shock Protein-70 is Associated With Decreased Frequency and Severity of Cellular Rejection in Cardiac Transplant Patients by Al Kassem, Hatem, Eapen, Danny J, Manocha, Pankaj, Gupta, Divya, Kay, Jenna, Obideen, Malik, Halista, Michael M, Kabani, Sarah S, Niaz, Adil, Kumar, Saket, Book, Wendy, Sikora, Sergey, Sperling, Laurence, Quyyumi, Arshed

“…Abstract only Background: Heat Shock Protein-70 (HSP70) is a highly conserved intracellular protein that is up-regulated in cells undergoing stressful stimuli…”
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Abstract 14971: Association Between Body Mass Index and Atrial Conduction Indices on Surface and Intracardiac Electrocardiogram in Patients With Supraventricular Arrhythmias by Al Kassem, Hatem, Deshmukh, Amrish, Aziz, Zaid, A. Besser, Stephanie, Ozcan, Cevher

“…IntroductionObesity is a modifiable risk factor for atrial fibrillation (AF). However, the mechanism by which obesity facilitates AF remains…”
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REDUCED BONE MASS PREDICTS IMPAIRED ARTERIAL ELASTICITY by Corrigan, Frank Edward, Eapen, Danny, Manocha, Pankaj, Hammadah, Muhammad, Kassem, Hatem Al, Vazquez, Jennifer, Cunningham, Lynn, Uphoff, Irina, Sperling, Laurence, Alexander, R. Wayne, Brigham, Kenneth L, Quyyumi, Arshed

“…After multivariate adjustment for age, race, gender, menopausal status, mean arterial pressure, body mass index, diabetes, tobacco use, HDL, total cholesterol…”
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SOLUBLE UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR IS AN INDEPENDENT PREDICTOR OF CARDIOVASCULAR OUTCOMES IN PATIENTS WITH LEFT VENTRICULAR SYSTOLIC DYSFUNCTION by Ghasemzadeh, Nima, Eapen, Danny, Tahhan, Ayman Samman, Kassem, Hatem Al, Khayata, Mohamed, Manocha, Pankaj, Merjaneh, Zahi, Nanjundappa, Ravi P. Avati, Malahfji, Maan M, Valiani, Kiran, Mheid, Ibhar Al, Reddy, Vijay A, Pielak, Tomasz, Thorball, Christian W, Patel, Riyaz, Sperling, Laurence, Lerakis, Stamatios, Quyyumi, Arshed

“…Methods 445 subjects with LVSD undergoing coronary angiography (age: 64 ± 12 years, 71% male, 22% black, 37% diabetes, 78% with CAD, EF: 29+10%, 34% with NYHA…”
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Abstract 19485: Migrant South Asian Women Have Increased Arterial Stiffness Compared to Black and White Women Residing in the United States by Eapen, Danny J, Manocha, Pankaj, Patel, Riyaz, Khan, Shafaat Ali, Menon, Vivek, Al Kassem, Hatem, Hammadah, Mohammad, Samman Tahhan, Ayman, Ghasemzadeh, Nima, Khayata, Mohamed, Kabbany, Mohammad Tarek, Asfari, Mohammad, Mohamed, Amr Mohamed Rashed, Khuram, Ashraf, Bhatia, Neal, Bellam, Naveen, Sher, Salman, Janjua, Uzair, Shah, Meera, Liu, Ying X, Sperling, Laurence, Quyyumi, Arshed

“…Abstract only Introduction: Death from cardiovascular disease (CVD) is proportionally higher in Black and South Asians (SA) residing in the United States…”
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AN AGGREGATE OF PATHWAY-RELATED BIOMARKERS PREDICT RISK OF ACUTE MYOCARDIAL INFARCTION AND DEATH by Eapen, Danny J, Manocha, Pankaj, Patel, Riyaz, Hammadah, Muhammad, Kabbany, Mohammad T, Veledar, Emir, Wassel, Christina, Alradawi, Suliman, Corrigan, Frank, Kassem, Hatem Al, Nanjundappa, Ravi, Mantini, Nicholas, Wilmot, Kobina A, Poole, Joseph, Neuman, Robert, Malayter, Dylan, Sikora, Sergey, Sperling, Laurence, Quyyumi, Arshed, Epstein, Stephen

“…Cox proportional hazard survival analyses and receiver operator statistics were performed with models adjusted for age, BMI, sex, race, smoking, diabetes,…”
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