Search Results - "Al Fayez, Nojoud"

Recent Advancement in mRNA Vaccine Development and Applications by Al Fayez, Nojoud, Nassar, Majed S, Alshehri, Abdullah A, Alnefaie, Meshal K, Almughem, Fahad A, Alshehri, Bayan Y, Alawad, Abdullah O, Tawfik, Essam A

“…Messenger RNA (mRNA) vaccine development for preventive and therapeutic applications has evolved rapidly over the last decade. The mRVNA vaccine has proven…”
Get full text

Chemically engineering the drug release rate of a PEG-paclitaxel conjugate using click and steric hindrance chemistries for optimal efficacy by Nguyen, Anne, Chao, Po-Han, Ong, Chun Yat, Rouhollahi, Elham, Fayez, Nojoud AL, Lin, Louis, Brown, Jennifer I., Böttger, Roland, Page, Brent, Wong, Harvey, Li, Shyh-Dar

“…A small molecule drug with poor aqueous solubility can be conjugated to a hydrophilic polymer like poly(ethylene glycol) (PEG) to form an amphiphilic…”
Get full text

Lipid-based nanoparticle technologies for liver targeting by Böttger, Roland, Pauli, Griffin, Chao, Po-Han, AL Fayez, Nojoud, Hohenwarter, Lukas, Li, Shyh-Dar

“…Liver diseases such as hepatitis, cirrhosis, and hepatocellular carcinoma are global health problems accounting for approximately 800 million cases and over 2…”
Get full text

Emerging Trends and Innovations in the Treatment and Diagnosis of Atherosclerosis and Cardiovascular Disease: A Comprehensive Review towards Healthier Aging by Alradwan, Ibrahim, Al Fayez, Nojoud, Alomary, Mohammad N, Alshehri, Abdullah A, Aodah, Alhassan H, Almughem, Fahad A, Alsulami, Khulud A, Aldossary, Ahmad M, Alawad, Abdullah O, Tawfik, Yahya M K, Tawfik, Essam A

“…Cardiovascular diseases (CVDs) are classed as diseases of aging, which are associated with an increased prevalence of atherosclerotic lesion formation caused…”
Get full text

The mechanism of Hepatocyte-Targeting and safety profile of Phospholipid-Free small unilamellar vesicles by AL Fayez, Nojoud, Böttger, Roland, Brown, Jennifer, Rouhollahi, Elham, Li, Shyh-Dar

“…[Display omitted] Phospholipid-free small unilamellar vesicles (PFSUVs) composed of cholesterol and TWEEN80 (5:1 mol ratio), with an average diameter of 60 nm,…”
Get full text

Hepatocyte-targeted delivery of imiquimod reduces hepatitis B virus surface antigen by AL Fayez, Nojoud, Rouhollahi, Elham, Ong, Chun Yat, Wu, Jiamin, Nguyen, Anne, Böttger, Roland, Cullis, Pieter R., Witzigmann, Dominik, Li, Shyh-Dar

“…Hepatitis B virus (HBV) can rapidly replicate in the hepatocytes after transmission, leading to chronic hepatitis, liver cirrhosis and eventually…”
Get full text

Improved Liver Delivery of Primaquine by Phospholipid-Free Small Unilamellar Vesicles with Reduced Hemolytic Toxicity by AL Fayez, Nojoud, Böttger, Roland, Rouhollahi, Elham, Cullis, Pieter R., Witzigmann, Dominik, Li, Shyh-Dar

“…Hemolytic toxicity caused by primaquine (PQ) is a high-risk condition that hampers the wide use of PQ to treat liver-stage malaria. This study demonstrated…”
Get full text

Development of a child-friendly oral drug formulation using liposomal multilamellar vesicle technology by AL Fayez, Nojoud, Böttger, Roland, Ghosh, Sreemoyee, Nakajima, Yushi, Chao, Po-Han, Rouhollahi, Elham, Nguyen, Anne, Cullis, Pieter R., Witzigmann, Dominik, Li, Shyh-Dar

“…[Display omitted] Many medicines are only available in solid dosage forms suitable for adults, and extemporaneous compounding is required to prepare…”
Get full text

Simultaneous Chromatographic Quantitation of Drug Substance and Excipients in Nanoformulations Using a Combination of Evaporative Light Scattering and Absorbance Detectors by Böttger, Roland, Chao, Po-Han, AL Fayez, Nojoud, Pauli, Griffin, Nguyen, Anne, Hohenwarter, Lukas, Bilal, Nida, Mohammed, Gubran Khalil, Knappe, Daniel, Hoffmann, Ralf, Li, Shyh-Dar

“…Nanomedicines including lipid- and polymer-based nanoparticles and polymer–drug conjugates enable targeted drug delivery for the treatment of numerous…”
Get full text

Altering the intra-liver distribution of phospholipid-free small unilamellar vesicles using temperature-dependent size-tunability by Vogler, Julian, Böttger, Roland, AL Fayez, Nojoud, Zhang, Wunan, Qin, Zhu, Hohenwarter, Lukas, Chao, Po-Han, Rouhollahi, Elham, Bilal, Nida, Chen, Naliangzi, Lee, Brandon, Chen, Christine, Wilkinson, Brayden, Kieffer, Timothy J., Kulkarni, Jayesh A., Cullis, Pieter R., Witzigmann, Dominik, Li, Shyh-Dar

“…We demonstrated that phospholipid-free small unilamellar vesicles (PFSUVs) composed of TWEEN 80 and cholesterol (25/75, mol%) could be fabricated using a…”
Get full text