Search Results - "Al Dulayymi, Juma'a R."

CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains by Chancellor, Andrew, Tocheva, Anna S., Cave-Ayland, Chris, Tezera, Liku, White, Andrew, Dulayymi, Juma’a R. Al, Bridgeman, John S., Tews, Ivo, Wilson, Susan, Lissin, Nikolai M., Tebruegge, Marc, Marshall, Ben, Sharpe, Sally, Elliott, Tim, Skylaris, Chris-Kriton, Essex, Jonathan W., Baird, Mark S., Gadola, Stephan, Elkington, Paul, Mansour, Salah

“…Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a major human pandemic. Germline-encoded mycolyl lipid-reactive (GEM) T cells are…”
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New synthetic lipid antigens for rapid serological diagnosis of tuberculosis by Jones, Alison, Pitts, Mark, Al Dulayymi, Juma'a R, Gibbons, James, Ramsay, Andrew, Goletti, Delia, Gwenin, Christopher D, Baird, Mark S

“…During pulmonary tuberculosis (PTB) antibodies are generated to trehalose esters of mycolic acids which are cell wall lipids of Mycobacterium tuberculosis…”
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An ELISA Using Synthetic Mycolic Acid-Based Antigens with DIVA Potential for Diagnosing Johne's Disease in Cattle by Mason, Paul S, Holder, Thomas, Robinson, Natasha, Smith, Brendan, Hameed, Rwoa'a T, Al Dulayymi, Juma'a R, Hughes, Valerie, Stevenson, Karen, Jones, Gareth J, Vordermeier, H Martin, Mc Kenna, Shawn, Baird, Mark S

“…Ante-mortem diagnosis of Johne's disease, caused by subsp. (MAP), is normally achieved through faecal culture, PCR, or serological tests, but agreement as to…”
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Synthesis of a Di-Mycoloyl Tri-Arabinofuranosyl Glycerol Fragment of the Mycobacterial Cell Wall, Based on Synthetic Mycolic Acids by Ali, Omar T, Mohammed, Mohsin O, Dulayymi, Juma'a R Al, Baird, Mark S

“…Fragments of mycobacterial cell walls such as arabinoglycerol mycolate and dimycoloyl diarabinoglycerol, comprising complex mixtures of mycolic acids, have…”
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The synthesis of mycobacterial dimycoloyl diarabinoglycerol based on defined synthetic mycolic acids by Ali, Omar T., Mohammed, Mohsin O., Gates, Paul J., Baird, Mark S., Al Dulayymi, Juma’a R.

“…[Display omitted] •Complex mixtures of natural dimycoloyl diarabinoglycerols isolated from mycobacteria are potent immune signalling agents.•They are…”
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Early antibody responses to lipid antigens in red deer infected with Mycobacterium bovis by Mason, Paul S., Risalde, Maria A., Gortázar, Christian, Garrido, Joseba M., Thomas, Dafydd A., Al Dulayymi, Juma’a R., Baird, Mark S.

“…The problem: Early and rapid diagnosis of bovine tuberculosis remains an issue of great interest. Aim: The aim of this study was to evaluate the use of…”
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Structure–function relationships of the antigenicity of mycolic acids in tuberculosis patients by Beukes, Mervyn, Lemmer, Yolandy, Deysel, Madrey, Al Dulayymi, Juma’a R., Baird, Mark S., Koza, Gani, Iglesias, Maximiliano M., Rowles, Richard R., Theunissen, Cornelia, Grooten, Johan, Toschi, Gianna, Roberts, Vanessa V., Pilcher, Lynne, Van Wyngaardt, Sandra, Mathebula, Nsovo, Balogun, Mohammed, Stoltz, Anton C., Verschoor, Jan A.

“…Cell wall mycolic acids (MA) from Mycobacterium tuberculosis (M.tb) are CD1b presented antigens that can be used to detect antibodies as surrogate markers of…”
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A re-investigation of the mycolic acids of Mycobacterium avium by Jones, Alison, Lee, Oona Y-C., Minnikin, David E., Baird, Mark S., Al Dulayymi, Juma’a R.

“…The isolation of the complete wax ester fraction of M. avium is described for the first time, including the trans-cyclopropane A as a major component. The…”
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Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern by Vander Beken, Seppe, Al Dulayymi, Juma'a R, Naessens, Thomas, Koza, Gani, Maza-Iglesias, Max, Rowles, Richard, Theunissen, Cornelia, De Medts, Jelle, Lanckacker, Ellen, Baird, Mark S, Grooten, Johan

“…Mycolic acids (MAs) occur in the cell wall of Mycobacterium tuberculosis as variable mixtures of different classes and chain lengths. Here, we address the…”
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Mycobacterium alvei (ω-1)-methoxy mycolic acids: Absolute stereochemistry and synthesis by Alhuwaymil, Zamzam S., Al-araj, Intisar Q.M., Al Dulayymi, Ahmad R., Jones, Alison, Gates, Paul J., Valero-Guillén, Pedro L., Baird, Mark S., Al Dulayymi, Juma’a R.

“…•Cells of Mycobacterium alvei are known to contain a unique set of mycolic acids with a (ω-1)-methoxy group; although the various enzymes in the biosynthesis…”
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Glucose monomycolates based on single synthetic mycolic acids by Sahb, Mohaned M., Al Dulayymi, Juma’a R., Baird, Mark S.

“…Synthetic 6-O-mycolylglucoses such as that shown have been prepared from a range of α-, keto and methoxy-mycolic acids. [Display omitted] •Glucose…”
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Synthetic trehalose esters of cis-alkene and diene α′-mycolic acids of Mycobacteria by Taher, Salam G., Muzael, Maged, Al Dulayymi, Juma’a R., Baird, Mark S.

“…[Display omitted] •The synthesis of alkene mycolic acid cord factors.•The synthesis of diene mycolic acid cord factors.•Synthetic trehalose…”
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Elevated serum antibody responses to synthetic mycobacterial lipid antigens among UK farmers: an indication of exposure to environmental mycobacteria? by Jones, Alison, Davies, Carys A, Fitch, Samuel, Al Dulayymi, Juma'a R, Gwenin, Christopher D, Gibbons, James, Williams, A. Prysor, Baird, Mark S

“…Background : mycobacterial cells contain complex mixtures of mycolic acid esters. These can be used as antigens recognised by antibodies in the serum of…”
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Diastereomeric cyclic tris-allenes by Mustafa, Hussein H, Baird, Mark S, Al Dulayymi, Juma'a R, Tverezovskiy, Viacheslav V

“…Both diastereomers of the tris-allene, cyclododeca-1,2,5,6,9,10-hexaene have been obtained using a triple cyclopropylidene-allene rearrangement. On the NMR…”
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A nine carbon homologating system for skip-conjugated polyenes by Mustafa, Hussein H., Baird, Mark S., Al Dulayymi, Juma’a R., Tverezovskiy, Viacheslav V.

“…•Ozonolysis of Z,Z,Z-Cylonona-1,4,7-triene.•Generation of a 1,9-difunctionalised Z,Z-3,6-nonadiene for application in synthesis.•Synthesis of polyunsaturated…”
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Sterculic Acid and Its Analogues Are Potent Inhibitors of Toxoplasma gondii by Hao, Pan, Alaraj, Intisar Q M, Dulayymi, Juma'a R Al, Baird, Mark S, Liu, Jing, Liu, Qun

“…Toxoplasmosis is a serious disease caused by Toxoplasma gondii, one of the most widespread parasites in the world. Lipid metabolism is important in the…”
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The synthesis of single enantiomers of mycobacterial ketomycolic acids containing cis-cyclopropanes by Koza, Gani, Theunissen, Cornelia, Al Dulayymi, Juma'a R., Baird, Mark S.

“…We report the syntheses of a single enantiomer of an unprotected ketomycolic acids containing a cis-cyclopropane and of related hydroxy-mycolic acids. The…”
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Thiol modified mycolic acids by Balogun, Mohammed O., Huws, Enlli H., Sirhan, Muthana M., Saleh, Ahmed D., Dulayymi, Juma’a R. Al, Pilcher, Lynne, Verschoor, Jan A., Baird, Mark S.

“…•The synthesis of thiol modified mycobacterial mycolic acids is reported.•Cyclic voltammetry shows these will bind to a gold surface.•This offers the potential…”
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The Synthesis of Single Enantiomers of α-Mycolic Acids of Mycobacterium­ tuberculosis and Related Organisms, with Alternative­ Cyclopropane Stereochemistries by Don Lawson, Chioma, Maza-Iglesias, Max, Sirhan, Muthana, Al Dulayymi, Jumaa, Baird, Mark

“…We report the synthesis of three stereoisomers of a mycolic acid from Mycobacterium tuberculosis containing a di-cis-cyclopropane and of two stereoisomers of a…”
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The synthesis of a single enantiomer of a major alpha-mycolic acid of Mycobacterium tuberculosis by Al Dulayymi, Juma'a R, Baird, Mark S, Roberts, Evan

“…We report a synthesis of a single enantiomer of a dicyclopropane containing mycolic acid from Mycobacterium tuberculosis; this method can be simply varied to…”
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