Search Results - "Al–Ashgar, Hamad"
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Association between HLA variations and chronic hepatitis B virus infection in Saudi Arabian patients
Published in PloS one (22-01-2014)“…Hepatitis B virus (HBV) infection is a leading cause of liver diseases including cirrhosis and hepatocellular carcinoma. Human leukocyte antigens (HLAs) play…”
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2
Association between IL-37 gene polymorphisms and risk of HBV-related liver disease in a Saudi Arabian population
Published in Scientific reports (09-05-2019)“…Interleukin-37 (IL-37) has recently been recognized as a strong anti-inflammatory cytokine having anti-tumor activity against hepatocellular carcinoma (HCC) in…”
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3
Efficacy of generic sofosbuvir with daclatasvir compared to sofosbuvir/ledipasvir in genotype 4 hepatitis C virus: A prospective comparison with historical control
Published in Health science reports (01-01-2023)“…Background and Aim Management of genotype 4 hepatitis C virus (HCV) has shifted to interferon‐free regimens with a high sustained virological response…”
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4
Prospective trial in Saudi Arabia comparing the 14-day standard triple therapy with the 10-day sequential therapy for treatment of Helicobacter pylori infection
Published in Saudi journal of gastroenterology (01-07-2015)“…Treatment success for Helicobacter pylori infection in Saudi Arabia is relatively unexplored. This prospective study compared the efficacy of sequential versus…”
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5
Hepatitis C genotype 4: genotypic diversity, epidemiological profile, and clinical relevance of subtypes in Saudi Arabia
Published in Saudi journal of gastroenterology (01-01-2013)“…Hepatitis C virus genotypes 4 (HCV-4) is the most prevalent genotype in Saudi Arabia, although it's various subtypes, mode and route of transmission remains…”
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6
Variations in DEPDC5 gene and its association with chronic hepatitis C virus infection in Saudi Arabia
Published in BMC infectious diseases (31-12-2014)“…Variations at DEPDC5 gene have been recently reported as genetic markers associated with hepatocellular carcinoma (HCC) progression in chronic HCV-infected…”
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7
Genetic variation in interleukin 28B and correlation with chronic hepatitis B virus infection in Saudi Arabian patients
Published in Liver international (01-08-2014)“…Background & Aims Several genome‐wide association studies have shown that genetic variations in the chromosomal region containing interleukin‐28B (IL28B) gene…”
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The Correlation Between Hepatitis B Virus Precore/Core Mutations and the Progression of Severe Liver Disease
Published in Frontiers in cellular and infection microbiology (22-10-2018)“…Viral mutations acquired during the course of chronic hepatitis B virus (HBV) infection are known to be associated with the progression and severity of…”
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Correlation between Genetic Variations and Serum Level of Interleukin 28B with Virus Genotypes and Disease Progression in Chronic Hepatitis C Virus Infection
Published in Journal of immunology research (01-01-2015)“…Recent studies have demonstrated that polymorphisms near the interleukin-28B (IL-28B) gene could predict the response to Peg-IFN-a/RBV combination therapy in…”
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10
Clinical, endoscopic, and radiologic features of three subtypes of achalasia, classified using high-resolution manometry
Published in Saudi journal of gastroenterology (01-05-2015)“…High-resolution manometry (HRM) has improved the accuracy of manometry in detecting achalasia and determining its subtypes. However, the correlation of…”
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Genetic variability of the core protein in hepatitis C virus genotype 4 in Saudi Arabian patients and its implication on pegylated interferon and ribavirin therapy
Published in Journal of translational medicine (06-04-2014)“…Hepatitis C virus (HCV) shows a remarkable genetic diversity, contributing to its high persistence and varied susceptibilities to antiviral treatment. Previous…”
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12
Hepatitis C virus core protein substitutions affect the response to pegylated-interferon and ribavirin therapy
Published in BMC genomics (02-04-2014)“…Doc number: P5…”
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13
HBsAg clearance in chronic hepatitis B patients with add-on pegylated interferon alfa-2a to ongoing tenofovir treatment: A randomized controlled study
Published in Saudi journal of gastroenterology (01-05-2017)“…The ideal end point of treatment for chronic hepatitis B virus (HBV) infection is sustained off-therapy hepatitis B surface antigen (HBsAg) loss with or even…”
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14
The Association of Toll-Like Receptor 4 Polymorphism with Hepatitis C Virus Infection in Saudi Arabian Patients
Published in BioMed research international (01-01-2014)“…Hepatitis C virus (HCV) is a single stranded RNA virus. It affects millions of people worldwide and is considered as a leading cause of liver diseases…”
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15
Response to: Treatment prolongation or quadruple therapy:- Individualization by geographical region
Published in Saudi journal of gastroenterology (01-01-2016)“…[...]as stated by the authors, the total number of strains resistant to clarithromycin in our study was low in both arms (10 in S10, and 3 in T14) and hence,…”
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PARK2 polymorphisms predict disease progression in patients infected with hepatitis C virus
Published in Annals of hepatology (01-11-2016)“…AbstractBackground The protein encoded by PARK2 gene is a component of the ubiquitin-proteasome system that mediates targeting of proteins for the degradation…”
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Lung transplantation triggered "jackhammer esophagus": a case report and review of literature
Published in Journal of neurogastroenterology and motility (01-07-2013)“…A 19-years-old girl was referred for lung transplant due to end stage lung disease secondary to idiopathic bilateral bronchiectasis. Her routine pre lung…”
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Wilson disease in 71 patients followed for over two decades in a tertiary center in Saudi Arabia: a retrospective review
Published in Annals of Saudi medicine (01-11-2012)“…Wilson disease (WD) is a rare autosomal recessive disease. Our objective was to describe the diverse patterns, therapies, and outcomes of this disease. A…”
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Acute onset autoimmune hepatitis: Clinical presentation and treatment outcomes
Published in Annals of hepatology (01-05-2019)“…AbstractIntroduction and aimAutoimmune hepatitis (AIH) may present acutely, which can rapidly progress to fulminant type. This pattern has been described…”
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Predictors of sustained virological response to a 48-week course of pegylated interferon alfa-2a and ribavirin in patients infected with hepatitis C virus genotype 4
Published in Annals of Saudi medicine (01-01-2009)“…Knowledge of the predictors of sustained viral response (SVR) to pegylated interferon (PEG-INF) alfa-2a and ribavirin (RBV) therapy in patients with hepatitis…”
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