Search Results - "Alípio Pinto"

Therapeutic Strategies to Protect the Central Nervous System against Shiga Toxin from Enterohemorrhagic Escherichia coli by Goldstein, Jorge, Nuñez-Goluboay, Krista, Pinto, Alipio

“…Infection with Shiga toxin-producing Escherichia coli (STEC) may cause hemorrhagic colitis, hemolytic uremic syndrome (HUS) and encephalopathy. The mortality…”
Get full text

Cognitive Deficits Found in a Pro-inflammatory State are Independent of ERK1/2 Signaling in the Murine Brain Hippocampus Treated with Shiga Toxin 2 from Enterohemorrhagic Escherichia coli by Berdasco, Clara, Pinto, Alipio, Blake, Mariano G., Correa, Fernando, Carbajosa, Nadia A. Longo, Celi, Ana B., Geoghegan, Patricia A., Cangelosi, Adriana, Nuñez, Myriam, Gironacci, Mariela M., Goldstein, Jorge

“…Shiga toxin 2 (Stx2) from enterohemorrhagic Escherichia coli (EHEC) produces hemorrhagic colitis, hemolytic uremic syndrome (HUS), and acute encephalopathy…”
Get full text

Role of Globotriaosylceramide in Physiology and Pathology by Celi, Ana Beatriz, Goldstein, Jorge, Rosato-Siri, María Victoria, Pinto, Alipio

“…At first glance, the biological function of globoside (Gb) clusters appears to be that of glycosphingolipid (GSL) receptors for bacterial toxins that mediate…”
Get full text

Shiga toxin 2 from enterohemorrhagic Escherichia coli induces reactive glial cells and neurovascular disarrangements including edema and lipid peroxidation in the murine brain hippocampus by Berdasco, Clara, Pinto, Alipio, Calabró, Valeria, Arenas, David, Cangelosi, Adriana, Geoghegan, Patricia, Evelson, Pablo, Goldstein, Jorge

“…Shiga toxin 2 from enterohemorrhagic Escherichia coli is the etiologic agent of bloody diarrhea, hemolytic uremic syndrome and derived encephalopathies that…”
Get full text

Relevance of Bacteriophage 933W in the Development of Hemolytic Uremic Syndrome (HUS) by Del Cogliano, Manuel E, Pinto, Alipio, Goldstein, Jorge, Zotta, Elsa, Ochoa, Federico, Fernández-Brando, Romina Jimena, Muniesa, Maite, Ghiringhelli, Pablo D, Palermo, Marina S, Bentancor, Leticia V

“…Hemolytic uremic syndrome (HUS), principally caused by shiga toxins (Stxs), is associated with Shiga toxin-producing (STEC) infections. We previously reported…”
Get full text

Dexamethasone rescues neurovascular unit integrity from cell damage caused by systemic administration of shiga toxin 2 and lipopolysaccharide in mice motor cortex by Pinto, Alipio, Jacobsen, Mariana, Geoghegan, Patricia A, Cangelosi, Adriana, Cejudo, María Laura, Tironi-Farinati, Carla, Goldstein, Jorge

“…Shiga toxin 2 (Stx2)-producing Escherichia coli (STEC) causes hemorrhagic colitis and hemolytic uremic syndrome (HUS) that can lead to fatal encephalopathies…”
Get full text

A translational murine model of sub-lethal intoxication with Shiga toxin 2 reveals novel ultrastructural findings in the brain striatum by Tironi-Farinati, Carla, Geoghegan, Patricia A, Cangelosi, Adriana, Pinto, Alipio, Loidl, C Fabian, Goldstein, Jorge

“…Infection by Shiga toxin-producing Escherichia coli causes hemorrhagic colitis, hemolytic uremic syndrome (HUS), acute renal failure, and also central nervous…”
Get full text

Promoter sequence of Shiga toxin 2 (Stx2) is recognized in vivo, leading to production of biologically active Stx2 by Bentancor, Leticia V, Mejías, Maria P, Pinto, Alípio, Bilen, Marcos F, Meiss, Roberto, Rodriguez-Galán, Maria C, Baez, Natalia, Pedrotti, Luciano P, Goldstein, Jorge, Ghiringhelli, Pablo D, Palermo, Marina S

“…Shiga toxins (Stx) are the main agent responsible for the development of hemolytic-uremic syndrome (HUS), the most severe and life-threatening systemic…”
Get full text

Evaluation of the air pollution-induced adverse effects reversibility on olfactory bulb by Freire, Agustina, Garcés, Mariana, Reynoso, Sofía, Diana, Octavio, Pinto, Alipio, Martinefski, Manuela, Diodati, Nahuel Mendez, Goldstein, Jorge, Tripodi, Valeria, Buchholz, Bruno, Alvarez, Silvia, Magnani, Natalia, Evelson, Pablo

Get full text

Dexamethasone prevents motor deficits and neurovascular damage produced by shiga toxin 2 and lipopolysaccharide in the mouse striatum by Pinto, Alipio, Cangelosi, Adriana, Geoghegan, Patricia, Goldstein, Jorge

“…Highlights • Stx2 breaks the Blood–Brain Barrier. • Stx2 damages the microvasculature, astrocytes and neurons. • LPS enhances its deleterious effects. • These…”
Get full text

Cytokines expression from altered motor thalamus and behavior deficits following sublethal administration of Shiga toxin 2a involve the induction of the globotriaosylceramide receptor by Arenas-Mosquera, David, Pinto, Alipio, Cerny, Natacha, Berdasco, Clara, Cangelosi, Adriana, Geoghegan, Patricia Andrea, Malchiodi, Emilio Luis, De Marzi, Mauricio, Goldstein, Jorge

“…Encephalopathy associated with hemolytic uremic syndrome is produced by enterohemorrhagic E. coli (EHEC) infection, which releases the virulence factors Shiga…”
Get full text

Promoter Sequence of Shiga Toxin 2 (Stx2) Is Recognized italic toggle="yes">In Vivo /italic>, Leading to Production of Biologically Active Stx2 by Leticia V. Bentancor, Maria P. Mejías, Alípio Pinto, Marcos F. Bilen, Roberto Meiss, Maria C. Rodriguez-Galán, Natalia Baez, Luciano P. Pedrotti, Jorge Goldstein, Pablo D. Ghiringhelli, Marina S. Palermo

“…ABSTRACT Shiga toxins (Stx) are the main agent responsible for the development of hemolytic-uremic syndrome (HUS), the most severe and life-threatening…”
Get full text

Anti-inflammatory agents reduce microglial response, demyelinating process and neuronal toxin uptake in a model of encephalopathy produced by Shiga Toxin 2 by Pinto, Alipio, Berdasco, Clara, Arenas-Mosquera, David, Cangelosi, Adriana, Geoghegan, Patricia A., Nuñez, Myriam C., Goldstein, Jorge

“…Infections by Enterohemorrhagic Escherichia coli may cause in addition to hemolytic uremic syndrome neurological disorders which may lead to fatal outcomes in…”
Get full text

Sub-Lethal Dose of Shiga Toxin 2 from Enterohemorrhagic Escherichia coli Affects Balance and Cerebellar Cytoarchitecture by D'Alessio, Luciana, Pinto, Alipio, Cangelosi, Adriana, Geoghegan, Patricia A, Tironi-Farinati, Carla, Brener, Gabriela J, Goldstein, Jorge

“…Shiga toxin producing Escherichia coli may damage the central nervous system before or concomitantly to manifested hemolytic-uremic syndrome symptoms. The…”
Get full text

Retinoid levels influence enterohemorrhagic Escherichia coli infection and Shiga toxin 2 susceptibility in mice by Cabrera, Gabriel, Fernández-Brando, Romina J, Abrey-Recalde, María Jimena, Baschkier, Ariela, Pinto, Alipio, Goldstein, Jorge, Zotta, Elsa, Meiss, Roberto, Rivas, Marta, Palermo, Marina S

“…Enterohemorrhagic Escherichia coli (EHEC) is a food-borne pathogen that produces Shiga toxin (Stx) and causes hemorrhagic colitis. Under some circumstances,…”
Get full text

Sub-Lethal Dose of Shiga Toxin 2 from Enterohemorrhagic Escherichia coli Affects Balance and Cerebellar Cythoarquitecture by D’Alessio, Luciana, Pinto, Alipio, Cangelosi, Adriana, Geoghegan, Patricia A., Tironi-Farinati, Carla, Brener, Gabriela J., Goldstein, Jorge

“…Shiga toxin producing Escherichia coli may damage the central nervous system before or concomitantly to manifested hemolytic uremic syndrome symptoms. The…”
Get full text