Search Results - "Akwo, Elvis A"
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Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program
Published in Nature communications (26-08-2019)“…Chronic kidney disease (CKD), defined by low estimated glomerular filtration rate (eGFR), contributes to global morbidity and mortality. Here we conduct a…”
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2
Neighborhood Deprivation Predicts Heart Failure Risk in a Low-Income Population of Blacks and Whites in the Southeastern United States
Published in Circulation Cardiovascular quality and outcomes (01-01-2018)“…Recent data suggest that neighborhood socioeconomic environment predicts heart failure (HF) hospital readmissions. We investigated whether neighborhood…”
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3
Association of Neighborhood Socioeconomic Context With Participation in Cardiac Rehabilitation
Published in Journal of the American Heart Association (11-10-2017)“…Background Cardiac rehabilitation (CR) is underutilized in the United States, with fewer than 20% of eligible patients participating in CR programs. Individual…”
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Racial disparities in end-stage renal disease in a high-risk population: the Southern Community Cohort Study
Published in BMC nephrology (07-08-2019)“…The Southern Community Cohort Study is a prospective study of low socioeconomic status (SES) blacks and whites from the southeastern US, where the burden of…”
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Mendelian randomization and the association of fibroblast growth factor-23 with heart failure with preserved ejection fraction
Published in Current opinion in nephrology and hypertension (01-07-2023)“…Observational data provide compelling evidence for elevated fibroblast growth factor-23 (FGF23) as a risk factor for heart failure (HF), particularly heart…”
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4234 Association of age at menopause with incident heart failure in the Southern Community Cohort Study
Published in Journal of clinical and translational science (01-06-2020)“…OBJECTIVES/GOALS: Early age at menopause has been linked to increased risk of cardiovascular disease; however, there is limited evidence for a relationship…”
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Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
Published in Nature genetics (01-01-2019)“…In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts…”
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Relation of the Dietary Approaches to Stop Hypertension Dietary Pattern to Heart Failure Risk and Socioeconomic Status (from the Southern Community Cohort Study)
Published in The American journal of cardiology (15-04-2022)“…The Dietary Approaches to Stop Hypertension (DASH) dietary pattern has been associated with a lower risk of incident heart failure (HF); however, previous…”
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9
1657-P: Performance of Insulin Sensitivity Indices vs. the Hyperinsulinemic Euglycemic Clamp in Chronic Kidney Disease
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Background: Patients with chronic kidney disease (CKD) are at high risk of cardiovascular disease (CVD) and premature death. Insulin resistance (IR) is…”
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Increased body mass index may be associated with greater risk of end-stage renal disease in whites compared to blacks: A nested case-control study
Published in BMC nutrition (01-01-2015)“…The relationship between body mass index (BMI) and end-stage renal disease (ESRD) may differ between blacks and whites due to underlying metabolic differences…”
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Association between reduced myocardial contraction fraction and cardiovascular disease outcomes: The Multi-Ethnic Study of Atherosclerosis
Published in International journal of cardiology (15-10-2019)“…The myocardial contraction fraction (MCF: stroke volume to myocardial volume) is a volumetric measure of left ventricular myocardial shortening. We examined…”
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Physical Activity, Sedentary Time, and Heart Failure Risk in Low-Income Black and White Adults Living in the Southeastern United States
Published in Circulation. Heart failure (01-07-2022)Get full text
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13
Depressive Symptoms and Incident Heart Failure Risk in the Southern Community Cohort Study
Published in JACC. Heart failure (01-04-2022)“…This study aims to examine whether greater frequency of depressive symptoms associates with increased risk of incident heart failure (HF). Depressive symptoms…”
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14
Race and Sex Differences in Modifiable Risk Factors and Incident Heart Failure
Published in JACC. Heart failure (01-02-2020)“…The purpose of this study was to examine race- and sex-based variation in the associations between modifiable risk factors and incident heart failure (HF)…”
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Association of Apparent Treatment-Resistant Hypertension With Differential Risk of End-Stage Kidney Disease Across Racial Groups in the Million Veteran Program
Published in Hypertension (Dallas, Tex. 1979) (01-08-2021)“…Apparent treatment-resistant hypertension (ATRH) has been linked to end-stage kidney disease (ESKD) and cardiovascular disease. We tested the hypothesis that…”
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Heart Failure Incidence and Mortality in the Southern Community Cohort Study
Published in Circulation. Heart failure (01-03-2017)“…There is a paucity of data on heart failure (HF) incidence among low-income and minority populations. Our objective was to investigate HF incidence and post-HF…”
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Effect Modification of Body Mass Index and Kidney Function on Insulin Sensitivity Among Patients With Moderate CKD and Healthy Controls
Published in Kidney international reports (01-11-2021)“…Insulin resistance and obesity are prevalent in chronic kidney disease (CKD) patients. The interaction of body mass index (BMI) and kidney function across the…”
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Peripheral Insulin Resistance Is Associated with Copeptin in Patients with Chronic Kidney Disease
Published in Kidney360 (30-09-2021)“…Insulin resistance is associated with cardiovascular disease risk and worsened kidney function. Patients with CKD have higher levels of insulin resistance…”
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Mendelian Randomization Analysis of Genetic Proxies of Thiazide Diuretics and the Reduction of Kidney Stone Risk
Published in JAMA network open (01-11-2023)“…Clinical trial data have called into question the efficacy of thiazide diuretics for the prevention of kidney stones. To identify whether there is an…”
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GLP1R Gene Expression and Kidney Disease Progression
Published in JAMA network open (01-10-2024)“…Glucagon-like peptide 1 receptor agonists (GLP-1RAs) may have nephroprotective properties beyond those related to weight loss and glycemic control. To…”
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