Search Results - "Akuma, Daniel"

Position-Specific Secondary Acylation Determines Detection of Lipid A by Murine TLR4 and Caspase-11 by Harberts, Erin M, Grubaugh, Daniel, Akuma, Daniel C, Shin, Sunny, Ernst, Robert K, Brodsky, Igor E

“…Immune sensing of the Gram-negative bacterial membrane glycolipid lipopolysaccharide (LPS) is both a critical component of host defense against bacterial…”
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Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS by Akuma, Daniel C, Wodzanowski, Kimberly A, Schwartz Wertman, Ronit, Exconde, Patrick M, Vázquez Marrero, Víctor R, Odunze, Chukwuma E, Grubaugh, Daniel, Shin, Sunny, Taabazuing, Cornelius, Brodsky, Igor E

“…Inflammatory caspases are cysteine protease zymogens whose activation following infection or cellular damage occurs within supramolecular organizing centers…”
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Early Outcome of Ambulatory Hernia Surgery in a Low-resource Setting: Experience from a Voluntary Surgical Outreach Program by Umezurike, Daniel Akuma, Ogbuanya, Aloysius Ugwu-Olisa, Olisa, Fabian, Oguonu, Amobi, Okoli, Chinwe, Eni, Uche Emmanuel, Obasi, Akputa A

“…Background: Progress in hernia surgery in Nigeria is hampered by poor health-seeking behavior, poverty, and ignorance. The disparity in the quality of health…”
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Differential expression of putative sodium-dependent cation-chloride cotransporters in Aedes aegypti by Piermarini, Peter M., Akuma, Daniel C., Crow, John C., Jamil, Taylor L., Kerkhoff, Willa G., Viel, Kenyatta C.M.F., Gillen, Christopher M.

“…The yellow fever mosquito, Aedes aegypti, has three genes that code for proteins with sequence similarity to vertebrate Na+-K+-Cl− cotransporters (NKCCs) of…”
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Knowledge, Attitude and Practice of Healthcare Managers to Medical Waste Management and Occupational Safety Practices: Findings from Southeast Nigeria by Anozie, Okechukwu Bonaventure, Lawani, Lucky Osaheni, Eze, Justus Ndulue, Mamah, Emmanuel Johnbosco, Onoh, Robinson Chukwudi, Ogah, Emeka Onwe, Umezurike, Daniel Akuma, Anozie, Rita Onyinyechi

“…Awareness of appropriate waste management procedures and occupational safety measures is fundamental to achieving a safe work environment, and ensuring patient…”
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116.3 Discovery and Evaluation of Nonnitrocatechol COMT Inhibitors for Treatment of Psychiatric Conditions by Barrow, James, Akuma, Daniel

“…Background: Catechol-O-methyltransferase (COMT) plays an important role in the termination of dopamine signaling in brain regions such as the prefrontal cortex…”
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Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS by Wodzanowski, Kimberly, Akuma, Daniel, Schwartz Wertman, Ronit, Exconde, Patrick, Vazquez Marrero, Victor, Odunze, Chukwuma, Grubaugh, Daniel, Shin, Sunny, Taabazuing, Cornelius, Brodsky, Igor

“…Inflammatory caspases are cysteine protease zymogens whose activation following infection or cellular damage occurs within supramolecular organizing centers…”
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Expression Pattern and RNAi Inhibition of Putative Sodium‐coupled Cation‐chloride Cotransporters in the Mosquito Aedes aegypti by Gillen, Christopher, Akuma, Daniel, Piermarini, Peter

“…Abstract only…”
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Structural and Functional Determinants of Caspase-11 Inflammasome Assembly during Innate Immune Defense by Akuma, Daniel Chukuemeka

“…Caspase-11 (Casp11) is a pattern-recognition receptor that senses cytosolic LPS. In response to binding cytosolic LPS, Casp11 assembles into a supramolecular…”
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Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility by Byers, Spencer, Buchler, Ingrid P., DePasquale, Michael, Rowley, Helen L., Kulkarni, Rajiv S., Pinder, Lucy, Kolobova, Anna, Li, Cailian, Au, Vinh, Akuma, Daniel, Zhang, Gongliang, Wei, Huijun, Cheetham, Sharon C., Barrow, James C., Carr, Gregory V.

“…Rationale Cognitive impairment is a primary feature of many neuropsychiatric disorders and there is a need for new therapeutic options. Catechol- O…”
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Optimization of 8‑Hydroxyquinolines as Inhibitors of Catechol O‑Methyltransferase by Buchler, Ingrid, Akuma, Daniel, Au, Vinh, Carr, Gregory, de León, Pablo, DePasquale, Michael, Ernst, Glen, Huang, Yifang, Kimos, Martha, Kolobova, Anna, Poslusney, Michael, Wei, Huijun, Swinnen, Dominique, Montel, Florian, Moureau, Florence, Jigorel, Emilie, Schulze, Monika-Sarah E. D, Wood, Martyn, Barrow, James C

“…A series of 8-hydroxy quinolines were identified as potent inhibitors of catechol O-methyltransferase (COMT) with selectivity for the membrane-bound form of…”
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Splenic injuries in native Africans: Presentation, limitations of management, and treatment outcomes in a civilian trauma service in Southeast Nigeria by Ogbuanya, Aloysius, Ajuluchuku, Uzoamaka, Nnadozie, Ugochukwu, Otuu, Onyeyirichi, Umezurike, Daniel, Kwento, Nwanneka

“…Background: Splenic trauma has emerged as a major global health burden, especially in developing nations with limited diagnostic and therapeutic facilities…”
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Expression of Sodium‐Dependent Cation‐Chloride Cotransporters in Adult and Larval Osmoregulatory Tissues of Aedes aegypti Mosquitoes by Jamil, Taylor L., Chen, Jiayu, Crow, John C., Kerkhoff, Willa G., Akuma, Daniel C., McQuiston, Alexander, Piermarini, Peter M., Gillen, Christopher M

“…Abstract only Yellow fever mosquitoes, Aedes aegypti , face diverse salt and water challenges. Larvae lose salt to the freshwater environment and gain water…”
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KCNH2-3.1 expression impairs cognition and alters neuronal function in a model of molecular pathology associated with schizophrenia by Carr, G V, Chen, J, Yang, F, Ren, M, Yuan, P, Tian, Q, Bebensee, A, Zhang, G Y, Du, J, Glineburg, P, Xun, R, Akhile, O, Akuma, D, Pickel, J, Barrow, J C, Papaleo, F, Weinberger, D R

“…Overexpression in humans of KCNH2 -3.1, which encodes a primate-specific and brain-selective isoform of the human ether-a-go-go-related potassium channel, is…”
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Design and Fabrication of a Hybrid Nanoparticle-Wick Heat Sink Structure for Thermoelectric Generators in Low-Grade Heat Utilization by Ozeh, Michael Daniel Akuma

“…Waste heat recovery is a multi-billion-dollar industry with a compound annual growth rate of 8.8% assessed between 2016 to 2024 and low-grade waste heat (<…”
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Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol O‑Methyltransferase by Ernst, Glen, Akuma, Daniel, Au, Vinh, Buchler, Ingrid P, Byers, Spencer, Carr, Gregory V, Defays, Sabine, de León, Pablo, Demaude, Thierry, DePasquale, Michael, Durieu, Véronique, Huang, Yifang, Jigorel, Emilie, Kimos, Martha, Kolobova, Anna, Montel, Florian, Moureau, Florence, Poslusney, Michael, Swinnen, Dominique, Vandergeten, Marie-Christine, Van houtvin, Nathalie, Wei, Huijun, White, Noelle, Wood, Martyn, Barrow, James C

“…A series of bicyclic pyridones were identified as potent inhibitors of catechol O-methyltransferase (COMT). Substituted benzyl groups attached to the basic…”
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Knowledge, Attitude and Practice of Healthcare Managers to Medical Waste Management and Occupational Safety Practices: Findings from Southeast Nigeria by Anozie, Okechukwu Bonaventure, Lawani, Lucky Osaheni, Eze, Justus Ndulue, Mamah, Emmanuel Johnbosco, Onoh, Robinson Chukwudi, Ogah, Emeka Onwe, Umezurike, Daniel Akuma, Anozie, Rita Onyinyechi

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