Search Results - "Aktas, Derya"

Design, synthesis and biological evaluation of 3,5-diaryl isoxazole derivatives as potential anticancer agents by Aktaş, Derya Anıl, Akinalp, Gökçen, Sanli, Fatma, Yucel, Mehmet Ali, Gambacorta, Nicola, Nicolotti, Orazio, Karatas, Omer Faruk, Algul, Oztekin, Burmaoglu, Serdar

“…IC50 :15.893 (μM) against PC3 cancer cell line Selectivity: 7.51 [Display omitted] The present study was carried out in the attempt to synthesize a new class…”
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MOVEMENT TO COASTAL TOWNS IN TURKEY: Urban Rescaling, Local Deregulation and New Prospects for the Predatory Construction Sector by Demirtaş‐Milz, Neslihan, Memişoğlu‐Gökbinar, Dilek, Aktaş, Derya, Ebe‐Güzgü, Pinar

“…In Turkey, as in many Mediterranean countries, the Covid‐19 pandemic enhanced the mobility of the country's affluent classes to coastal towns. Many decided to…”
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Synthesis and anti-proliferative activity of fluoro-substituted chalcones by Burmaoglu, Serdar, Algul, Oztekin, Anıl, Derya Aktas, Gobek, Arzu, Duran, Gulay Gulbol, Ersan, Ronak Haj, Duran, Nizami

“…[Display omitted] A series of novel fluoro-substituted chalcone derivatives have been synthesized. All synthesized compounds were characterized by 1H nuclear…”
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Effects of Different Seed Substances on Anaerobic Degradation of Municipal Solid Waste in Recirculated Bioreactor by Agdag, Osman Nuri, Aktas, Derya, Simsek, Omer

“…Alternatively, to traditional landfilling, using bioreactor landfilling and anaerobic treatment technology has been increasing recently, which facilitates more…”
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Assessing the Antiangiogenic Effects of Chalcones and Their Derivatives by Burmaoglu, Serdar, Gobek, Arzu, Anil, Derya Aktas, Alagoz, Mehmet Abdullah, Guner, Adem, Güler, Cem, Hepokur, Ceylan, Karabay Yavasoglu, N. Ulku, Algul, Oztekin

“…Pathological angiogenesis plays a critical role in tumorigenesis and tumor progression, and anti-angiogenesis therapies have evinced promising antitumor…”
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New chalcone derivatives as effective against SARS-CoV-2 agent by Duran, Nizami, Polat, M Fatih, Aktas, Derya Anil, Alagoz, M Abdullah, Ay, Emrah, Cimen, Funda, Tek, Erhan, Anil, Baris, Burmaoglu, Serdar, Algul, Oztekin

“…Flavonoids and related compounds, such as quercetin-based antiviral drug Gene-Eden-VIR/Novirin, inhibit the protease of severe acute respiratory syndrome…”
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Investigation of the effect of binding material and Thiobacillus thiooxidans on the heavy metals mobilization in the mine tailings by Aktaş, Derya, Akıncı, Görkem, Güven, Duyuşen

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Investigation of Some Metabolic Enzyme Inhibition Properties of Novel Chalcone‐Cu Complexes by Ebiri, Rustem, Turgut, Muhammet, Aktas Anil, Derya, Demir, Yeliz, Saglamtas, Ruya, Abdullah Alagoz, M., Algul, Oztekin, Burmaoglu, Serdar

“…Fourteen novel Chalcone‐Cu complexes were effectively synthesized in this work. The newly synthesized Chalcone‐Cu complexes were assessed for their effects on…”
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Design of potent fluoro-substituted chalcones as antimicrobial agents by Burmaoglu, Serdar, Algul, Oztekin, Gobek, Arzu, Aktas Anil, Derya, Ulger, Mahmut, Erturk, Busra Gul, Kaplan, Engin, Dogen, Aylin, Aslan, Gönül

“…Owing to ever-increasing bacterial and fungal drug resistance, we attempted to develop novel antitubercular and antimicrobial agents. For this purpose, we…”
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Novel and Stereospecific Synthesis of (2S)-3-(2,4,5-Trifluorophenyl)propane-1,2-diol from D-Mannitol by Aktaş, Derya, Fıstıkçı, Meryem, Gündoğdu, Özlem, Seçen, Hasan, Şahin, M. Fethi, Altundaş, Ramazan, Kara, Yunus

“…A stereospecific synthesis of (2S)‐3‐(2,4,5‐trifluorophenyl)propane‐1,2‐diol from D‐mannitol has been developed. The reaction of…”
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Enantiospecific Synthesis of (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Using (S)-Serine as a Chiral Pool by Köse, Aytekin, Gündoğdu, Özlem, Aktaş, Derya, Fıstıkçı, Meryem, Altundaş, Ramazan, Seçen, Hasan, Kara, Yunus

“…Starting from (S)‐serine, a new method was developed for the synthesis of the β‐amino acid part of sitagliptin in ten steps and with an overall yield of 30%…”
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Design, synthesis, biological evaluation and molecular docking studies of novel 1H-1,2,3-Triazole derivatives as potent inhibitors of carbonic anhydrase, acetylcholinesterase and aldose reductase by Anil, Derya Aktas, Aydin, Busra Ozturk, Demir, Yeliz, Turkmenoglu, Burcin

“…•A series of 1H-1,2,3 triazole derivatives were synthesized by the Banert cascade reaction using click chemistry.•The inhibitory effects of these compounds on…”
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Teknoloji için çevre, çevre için teknoloji: Enerji sektöründe blok zinciri uygulamaları by Aktaş,Derya

“…2008’de Nakamoto’nun blok zincirini ortaya koymasının ardından bu teknolojinin sadece kripto paralarla ilgili olmadığını keşfetmek uzun sürmemiştir. Literatüre…”
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An Unexpended Stereocontrolled Rearrangement of Ethyl 4‐Hydroxy‐4‐(substituted phenyl)‐2‐butynoate to Tetrasubstituted Alkenes with MeSOCl 2 by Anil, Derya Aktas

“…Tetrasubstituted alkene derivatives are synthetically important compounds and one of the important research areas in organic chemistry. Stereoselective…”
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An Unexpended Stereocontrolled Rearrangement of Ethyl 4‐Hydroxy‐4‐(substituted phenyl)‐2‐butynoate to Tetrasubstituted Alkenes with MeSOCl2 by Anil, Derya Aktas

“…Tetrasubstituted alkene derivatives are synthetically important compounds and one of the important research areas in organic chemistry. Stereoselective…”
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Organohalogen chalcones: design, synthesis, ADMET prediction, molecular dynamics study and inhibition effect on acetylcholinesterase and carbonic anhydrase by Aydin, Busra Ozturk, Anil, Derya Aktas, Demir, Yeliz, Alagoz, Mehmet Abdullah

“…In an effort to discover potential acetylcholinesterase (AChE) and carbonic anhydrase (CA) inhibitors, a novel series of organohalogen chalcone derivatives…”
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Exploring enzyme inhibition profiles of novel halogenated chalcone derivatives on some metabolic enzymes: Synthesis, characterization and molecular modeling studies by Anil, Derya Aktas, Polat, M. Fatih, Saglamtas, Ruya, Tarikogullari, Ayse H., Alagoz, M. Abdullah, Gulcin, Ilhami, Algul, Oztekin, Burmaoglu, Serdar

“…Enzyme inhibition is a very active area of research in drug design and development. Chalcone derivatives have a broad enzyme inhibitory activity and function…”
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New Fluoro‐ and Trifluoromethyl‐Substituted Trimethoxychalcones as Anticancer Agents: Synthesis, Bio‐evaluation, and Computational Studies by Polat, M. Fatih, Anil, Derya Aktas, Ozkemahli, Gizem, Turkmenoglu, Burcin, Hepokur, Ceylan, Burmaoglu, Serdar, Algul, Oztekin

“…We designed and synthesized a novel series of trimethoxy chalcones with CF3 or F substituents at various positions of ring B, characterized using IR, NMR…”
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Maden sahası atıklarında bağlayıcı materyal ve Thiobacillus thiooxidans varlığının ağır metal mobilizasyonuna etkisinin araştırılması by Aktaş,Derya, Akıncı,Görkem, Güven,Elif Duyuşen

“…Çalışmada, terk edilmiş bir Pb-Zn madeni ve işletilmekte olan bor madeni atıklarındaki arsenik (As), bor (B), kadmiyum (Cd), bakır (Cu), mangan (Mn), kurşun…”
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Novel and enantioselective syntheses of (R)- and (S)-3-hydroxy-4-(2,4,5-trifluorophenyl)butanoic acid: a synthon for sitagliptin and its derivatives by Fistikci, Meryem, Gundogdu, Ozlem, Aktas, Derya, Secen, Hasan, Sahin, M. Fethi, Altundas, Ramazan, Kara, Yunus

“…A new synthetic strategy for (R)- and (S)-3-hydroxy-4-(2,4,5-trifluorophenyl)butanoic acid, a building block in the preparation of sitagliptin and its…”
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