Search Results - "Akslen, L A"

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  1. 1

    A novel age-related gene expression signature associates with proliferation and disease progression in breast cancer by Ingebriktsen, L. M., Finne, K., Akslen, L. A., Wik, E.

    Published in British journal of cancer (09-11-2022)
    “…Background and objective Breast cancer (BC) diagnosed at ages <40 years presents with more aggressive tumour phenotypes and poorer clinical outcome compared to…”
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  2. 2

    Molecular subtypes, histopathological grade and survival in a historic cohort of breast cancer patients by Engstrøm, M. J., Opdahl, S., Hagen, A. I., Romundstad, P. R., Akslen, L. A., Haugen, O. A., Vatten, L. J., Bofin, A. M.

    Published in Breast cancer research and treatment (01-08-2013)
    “…Molecular subtyping of breast cancer may provide additional prognostic information regarding patient outcome. However, its clinical significance remains to be…”
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  3. 3

    Elevated expression of Aurora-A/AURKA in breast cancer associates with younger age and aggressive features by Ingebriktsen, L M, Humlevik, R O C, Svanøe, A A, Sæle, A K M, Winge, I, Toska, K, Kalvenes, M B, Davidsen, B, Heie, A, Knutsvik, G, Askeland, C, Stefansson, I M, Hoivik, E A, Akslen, L A, Wik, E

    Published in Breast cancer research : BCR (28-08-2024)
    “…Aurora kinase A (AURKA) is reported to be overexpressed in breast cancer. In addition to its role in regulating cell cycle and mitosis, studies have reported…”
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    Pre-diagnostic high-sensitive C-reactive protein and breast cancer risk, recurrence, and survival by Frydenberg, H., Thune, I., Lofterød, T., Mortensen, E. S., Eggen, A. E., Risberg, T., Wist, E. A., Flote, V. G., Furberg, A-S, Wilsgaard, T., Akslen, L. A., McTiernan, A.

    Published in Breast cancer research and treatment (01-01-2016)
    “…Inflammation may initiate and promote breast cancer development, and be associated with elevated circulating levels of inflammation markers. A total of eight…”
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  6. 6

    Body size and thyroid cancer in two million Norwegian men and women by ENGELAND, A, TRETLI, S, AKSLEN, L. A, BJØRGE, T

    Published in British journal of cancer (07-08-2006)
    “…We investigated relations between measured body mass index (BMI) and stature and thyroid cancer (3046 cases) in a large Norwegian cohort of more than two…”
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  7. 7

    Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis by Fluge, Ø, Gravdal, K, Carlsen, E, Vonen, B, Kjellevold, K, Refsum, S, Lilleng, R, Eide, T J, Halvorsen, T B, Tveit, K M, Otte, A P, Akslen, L A, Dahl, O

    Published in British journal of cancer (20-10-2009)
    “…Background: Enhancer of zeste homologue 2 (EZH2) is a member of the Polycomb group of genes that is involved in epigenetic silencing and cell cycle regulation…”
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    KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer by Birkeland, E, Wik, E, Mjøs, S, Hoivik, E A, Trovik, J, Werner, H M J, Kusonmano, K, Petersen, K, Raeder, M B, Holst, F, Øyan, A M, Kalland, K-H, Akslen, L A, Simon, R, Krakstad, C, Salvesen, H B

    Published in British journal of cancer (04-12-2012)
    “…Background: Three quarter of endometrial carcinomas are treated at early stage. Still, 15 to 20% of these patients experience recurrence, with little effect…”
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  10. 10

    Increased microvascular proliferation is negatively correlated to tumour blood flow and is associated with unfavourable outcome in endometrial carcinomas by Haldorsen, I S, Stefansson, I, Grüner, R, Husby, J A, Magnussen, I J, Werner, H M J, Salvesen, Ø O, Bjørge, L, Trovik, J, Taxt, T, Akslen, L A, Salvesen, H B

    Published in British journal of cancer (07-01-2014)
    “…Background: We aimed to study the angiogenic profile based on histomorphological markers in endometrial carcinomas in relation to imaging parameters obtained…”
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  11. 11

    Loss of GPER identifies new targets for therapy among a subgroup of ERα-positive endometrial cancer patients with poor outcome by Krakstad, C, Trovik, J, Wik, E, Engelsen, I B, Werner, H M J, Birkeland, E, Raeder, M B, Øyan, A M, Stefansson, I M, Kalland, K H, Akslen, L A, Salvesen, H B

    Published in British journal of cancer (08-05-2012)
    “…Background: The G protein-coupled oestrogen receptor, GPER, has been suggested as an alternative oestrogen receptor. Our purpose was to investigate the…”
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  12. 12

    High BMI is significantly associated with positive progesterone receptor status and clinico-pathological markers for non-aggressive disease in endometrial cancer by Mauland, K K, Trovik, J, Wik, E, Raeder, M B, Njølstad, T S, Stefansson, I M, Øyan, A M, Kalland, K H, Bjørge, T, Akslen, L A, Salvesen, H B

    Published in British journal of cancer (15-03-2011)
    “…Background: Endometrial cancer incidence is increasing in industrialised countries. High body mass index (BMI, kg m −2 ) is associated with higher risk for…”
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  13. 13

    Independent prognostic value of the basal-like phenotype of breast cancer and associations with EGFR and candidate stem cell marker BMI-1 by Arnes, J B, Collett, K, Akslen, L A

    Published in Histopathology (01-02-2008)
    “…Aims:  To study the relationship between basal‐like breast cancers, epidermal growth factor receptor (EGFR) and candidate stem cell markers (BMI‐1, EZH2,…”
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  14. 14

    Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer by Akslen, L A, Straume, O, Geisler, S, Sørlie, T, Chi, J-T, Aas, T, Børresen-Dale, A-L, Lønning, P E

    Published in British journal of cancer (28-06-2011)
    “…Background: Glomeruloid microvascular proliferation (GMP), a novel histology-based angiogenesis marker, has been associated with decreased survival in several…”
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  15. 15

    Low BMI-1 expression is associated with an activated BMI-1-driven signature, vascular invasion, and hormone receptor loss in endometrial carcinoma by Engelsen, I B, Mannelqvist, M, Stefansson, I M, Carter, S L, Beroukhim, R, Øyan, A M, Otte, A P, Kalland, K H, Akslen, L A, Salvesen, H B

    Published in British journal of cancer (20-05-2008)
    “…We studied the expression of polycomb group (PcG) protein BMI-1 in a large population-based patient series of endometrial carcinomas in relation to clinical…”
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  16. 16

    Strong expression of ID1 protein is associated with decreased survival, increased expression of ephrin-A1 EPHA2, and reduced thrombospondin-1 in malignant melanoma by Straume, O, Akslen, L A

    Published in British journal of cancer (17-10-2005)
    “…The ID1 protein, an inhibitor of basic helix-loop-helix transcription factors, has been involved in multiple cellular processes including cell cycle…”
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  17. 17

    Prognostic significance of histologic grading compared with subclassification of papillary thyroid carcinoma by Akslen, Lars A., LiVolsi, Virginia A.

    Published in Cancer (15-04-2000)
    “…BACKGROUND Papillary thyroid carcinomas represent a diversity of morphologic subtypes and variants, but to the authors' knowledge the prognostic significance…”
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    Expression of epidermal growth factor receptor in relation to BRCA1 status, basal-like markers and prognosis in breast cancer by Arnes, J B, Bégin, L R, Stefansson, I, Brunet, J-S, Nielsen, T O, Foulkes, W D, Akslen, L A

    Published in Journal of clinical pathology (01-02-2009)
    “…BRCA1-related breast cancer is associated with a basal-like phenotype, and is frequently oestrogen receptor (ER) and HER2 negative. The expression of epidermal…”
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  19. 19

    Women treated with breast conserving surgery do better than those with mastectomy independent of detection mode, prognostic and predictive tumor characteristics by Hofvind, S, Holen, Å, Aas, T, Roman, M, Sebuødegård, S, Akslen, L.A

    Published in European journal of surgical oncology (01-10-2015)
    “…Abstract Background Primary breast conserving treatment (BCT) is well known to have similar long-term survival as mastectomy in breast cancer patients…”
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  20. 20

    Significance of tumour‐associated macrophages, vascular endothelial growth factor and thrombospondin‐1 expression for tumour angiogenesis and prognosis in endometrial carcinomas by Salvesen, Helga B., Akslen, Lars A.

    Published in International journal of cancer (22-10-1999)
    “…Angiogenesis is a key process in tumour growth and metastasis, and microvessel density has been found to influence the prognosis of endometrial carcinoma…”
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