Search Results - "Akselsen, H"
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Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes
Published in Diabetologia (01-04-2008)“…Background/hypothesis HLA, INS, PTPN22 and CTLA4 are considered to be confirmed type 1 diabetes susceptibility genes. HLA, PTPN22 and CTLA4 are known to be…”
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Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex
Published in Genes and immunity (01-06-2009)“…The high-risk human leukocyte antigen ( HLA ) -DRB1 , DQA1 and DQB1 alleles cannot explain the entire type 1 diabetes (T1D) association observed within the…”
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FTO genotype and weight gain in obese and normal weight adults from a Norwegian population based cohort (the HUNT study)
Published in Experimental and clinical endocrinology & diabetes (01-10-2010)“…The fat mass and obesity associated gene ( FTO) is associated with bodyweight and obesity. The aim of this study was to investigate if FTO genotype affects…”
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A TLR2 polymorphism is associated with type 1 diabetes and allergic asthma
Published in Genes and immunity (01-03-2009)“…Type 1 diabetes (T1D) and allergic asthma are immune-mediated diseases. Pattern recognition receptors are proteins expressed by cells in the immune system to…”
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HLA-DRB1, -DQA1 and -DQB1 Alleles and Haplotypes in First-Generation Pakistani Immigrants in Norway
Published in Scandinavian journal of immunology (01-04-2012)“…Human leucocyte antigen (HLA) polymorphisms among immigrants from Pakistan have not been well investigated. Immigration to Norway started in the late 1960s for…”
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Evidence of at least two type 1 diabetes susceptibility genes in the HLA complex distinct from HLA-DQB1, -DQA1 and -DRB1
Published in Genes and immunity (01-01-2003)“…Susceptibility to, and protection against development of type 1 diabetes (T1D) are primarily associated with the highly polymorphic exon 2 sequences of the HLA…”
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The Predisposition to Type 1 Diabetes Linked to the Human Leukocyte Antigen Complex Includes at Least One Non–Class II Gene
Published in American journal of human genetics (01-03-1999)“…The human leukocyte antigen (HLA) complex, encompassing 3.5 Mb of DNA from the centromeric HLA-DPB2 locus to the telomeric HLA-F locus on chromosome 6p21,…”
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Applying Multiple Grids to a Multi-Field Model - The Resolution Requirements of Individual Fields in the Two-Fluid Model for 1D Pipe Flow
Published in Journal of dispersion science and technology (03-10-2015)“…Modeling two-phase pipe flow commonly involves gas and liquid fields which can differ greatly in density and compressibility. The physical scales governing the…”
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HLA Dr-Dq haplotypes and the TNFA-308 polymorphism: associations with asthma and allergy
Published in Allergy (01-09-2007)“…The HLA (human leukocyte antigen) class II genes DQB1 and DRB1 and the Tumor Necrosis Factor α gene (TNFA) within the HLA complex (chromosome 6p21) have been…”
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Linkage disequilibrium and haplotype blocks in the MHC vary in an HLA haplotype specific manner assessed mainly by DRB103 and DRB104 haplotypes
Published in Genes and immunity (01-03-2006)“…First generation linkage disequilibrium (LD) and haplotype maps of the human major histocompatibility complex (MHC) have been generated in order to aid the…”
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HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection
Published in Diabetes (New York, N.Y.) (01-01-1997)“…HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection. D E Undlien , T Friede , H G Rammensee , G…”
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HLA-encoded genetic predisposition in IDDM : DR4 subtypes may be associated with different degrees of protection
Published in Diabetes (New York, N.Y.) (1997)“…Recent studies have shown that the risk conferred by the high-risk DQA1*03-DQB1*0302 (DQ8) haplotype is modified by the DRB1*04 allele that is also carried by…”
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Polymorphisms in the gene encoding thymus-specific serine protease in the extended HLA complex: a potential candidate gene for autoimmune and HLA-associated diseases
Published in Genes and immunity (01-08-2002)“…Positive selection plays a role, together with negative selection, in the prevention of autoimmunity. Thymus-specific serine protease is highly expressed in…”
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An increased risk of cervical intra‐epithelial neoplasia grade II‐III among human papillomavirus positive patients with the HLA‐DQA10102‐DQB10602 haplotype: A population‐based case–control study of Norwegian women
Published in International journal of cancer (30-03-1998)“…Several recent studies have reported different associations between HLA specificities and human papillomavirus (HPV)‐associated disease of the cervix. We…”
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Application and Interpretation of Transmission/Disequilibrium Tests: Transmission of HLA-DQ Haplotypes to Unaffected Siblings in 526 Families with Type 1 Diabetes
Published in American journal of human genetics (01-02-2000)“…It is widely believed that, if a genetic marker shows a transmission distortion in patients by the transmission/disequilibrium test (TDT), then a transmission…”
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Insulin gene region-encoded susceptibility to IDDM maps upstream of the insulin gene
Published in Diabetes (New York, N.Y.) (01-06-1995)“…Insulin gene region-encoded susceptibility to IDDM maps upstream of the insulin gene. D E Undlien , S T Bennett , J A Todd , H E Akselsen , I Ikäheimo , H…”
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Insulin gene region-encoded susceptibility to IDDM maps upstream of the insulin gene
Published in Diabetes (New York, N.Y.) (01-06-1995)“…The gene region on chromosome 11p15.5 known to be involved in insulin-dependent diabetes mellitus (IDDM) susceptibility was recently mapped to a 4.1-kilobase…”
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FOXP3 polymorphisms in type 1 diabetes and coeliac disease
Published in Journal of autoimmunity (01-09-2006)“…The FOXP3 gene encodes a transcription factor thought to be essential for the development and function of T regulatory cells. Two previous studies have tested…”
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No independent associations of LMP2 and LMP7 polymorphisms with susceptibility to develop IDDM
Published in Diabetes (New York, N.Y.) (01-02-1997)“…No independent associations of LMP2 and LMP7 polymorphisms with susceptibility to develop IDDM. D E Undlien , H E Akselsen , G Joner , K Dahl-Jørgensen , O…”
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No independent associations of LMP2 and LMP7 polymorphisms with susceptibility to develop IDDM
Published in Diabetes (New York, N.Y.) (01-02-1997)“…Results from a recent study suggested that polymorphisms within the HLA class II genes LMP2 and LMP7 were associated with the susceptibility for developing…”
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