Search Results - "Akpinar, Birce"

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    5-Fluorouracil Mediated Cell Death Signaling in Colon Carcinoma Cells by Akpinar, Birce

    Published 01-01-2016
    “…Colorectal cancer (CRC) is the third most common form of cancer in the world. 5- Fluorouracil (5-FU) belongs to the fluoropyrimidine-type of drugs and is…”
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    Dissertation
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    A caspase-2-RFXANK interaction and its implication for MHC class II expression by Forsberg, Jeremy, Li, Xinge, Akpinar, Birce, Salvatori, Roger, Ott, Martin, Zhivotovsky, Boris, Olsson, Magnus

    Published in Cell death & disease (23-01-2018)
    “…Despite recent achievements implicating caspase-2 in tumor suppression, the enzyme stands out from the apoptotic caspase family as a factor whose function…”
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    Journal Article
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    5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53 by Akpinar, Birce, Bracht, Ethiene V, Reijnders, Dorin, Safarikova, Barbora, Jelinkova, Iva, Grandien, Alf, Vaculova, Alena Hyrslova, Zhivotovsky, Boris, Olsson, Magnus

    Published in Oncotarget (22-12-2015)
    “…Despite recent advances in targeted therapeutics, administration of 5-fluorouracil (5-FU) remains a common clinical strategy for post-surgical treatment of…”
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    Journal Article
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    Aberrant DR5 transport through disruption of lysosomal function suggests a novel mechanism for receptor activation by Akpinar, Birce, Safarikova, Barbora, Laukova, Jarmila, Debnath, Shubhranshu, Vaculova, Alena Hyrslova, Zhivotovsky, Boris, Olsson, Magnus

    Published in Oncotarget (06-09-2016)
    “…To examine reciprocal or unilateral implications between two cell destruction processes, autophagy and apoptosis, in 5-Fluorouracil (5-FU)-treated tumor cells,…”
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    Journal Article
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