Search Results - "Akova, M."

Sulbactam-containing β-lactamase inhibitor combinations by Akova, M.

“…Sulbactam irreversibly inhibits the hydrolytic activity of β-lactamases. This compound is commercially available in combination with either ampicillin or…”
Get full text

Emergence of ceftazidime/avibactam resistance in carbapenem-resistant Klebsiella pneumoniae in China by Zhang, P., Shi, Q., Hu, H., Hong, B., Wu, X., Du, X., Akova, M., Yu, Y.

“…The aim was to investigate the activity of ceftazidime/avibactam (CAZ/AVI) against carbapenem-resistant Klebsiella pneumoniae (CRKP) and identify the…”
Get full text

ESCMID† and ECMM‡ joint clinical guidelines for the diagnosis and management of rare invasive yeast infections by Arendrup, M.C., Boekhout, T., Akova, M., Meis, J.F., Cornely, O.A., Lortholary, O.

“…The mortality associated with invasive fungal infections remains high with that involving rare yeast pathogens other than Candida being no exception. This is…”
Get full text

Interventional strategies and current clinical experience with carbapenemase-producing Gram-negative bacteria by Akova, M., Daikos, G.L., Tzouvelekis, L., Carmeli, Y.

“…The wide dissemination of carbapenemase-producing Gram-negatives (CPGNs), including enterobacterial species and non-fermenters, has caused a public health…”
Get full text

Zygomycosis in Europe: analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007 by Skiada, A., Pagano, L., Groll, A., Zimmerli, S., Dupont, B., Lagrou, K., Lass-Florl, C., Bouza, E., Klimko, N., Gaustad, P., Richardson, M., Hamal, P., Akova, M., Meis, J.F., Rodriguez-Tudela, J.-L., Roilides, E., Mitrousia-Ziouva, A., Petrikkos, G.

“…Zygomycosis is an important emerging fungal infection, associated with high morbidity and mortality. The Working Group on Zygomycosis of the European…”
Get full text

The global threat of antimicrobial resistance: science for intervention by Roca, I, Akova, M, Baquero, F, Carlet, J, Cavaleri, M, Coenen, S, Cohen, J, Findlay, D, Gyssens, I, Heure, O.E, Kahlmeter, G, Kruse, H, Laxminarayan, R, Liébana, E, López-Cerero, L, MacGowan, A, Martins, M, Rodríguez-Baño, J, Rolain, J.-M, Segovia, C, Sigauque, B, Tacconelli, E, Wellington, E, Vila, J

“…Abstract In the last decade we have witnessed a dramatic increase in the proportion and absolute number of bacterial pathogens resistant to multiple…”
Get full text

Controlling the spread of carbapenemase-producing Gram-negatives: therapeutic approach and infection control by Carmeli, Y., Akova, M., Cornaglia, G., Daikos, G.L., Garau, J., Harbarth, S., Rossolini, G.M., Souli, M., Giamarellou, H.

“…Although the rapid spread of carbapenemase-producing Gram-negatives (CPGNs) is providing the scientific community with a great deal of information about the…”
Get full text

Multidrug-resistant bacteria in solid organ transplant recipients by Cervera, C., van Delden, C., Gavaldà, J., Welte, T., Akova, M., Carratalà, J.

“…Bacteria are the leading cause of infections after solid organ transplantation. In recent years, a progressive growth in the incidence of multidrug-resistant…”
Get full text

European guidelines for empirical antibacterial therapy for febrile neutropenic patients in the era of growing resistance: summary of the 2011 4th European Conference on Infections in Leukemia by Averbuch, Diana, Orasch, Christina, Cordonnier, Catherine, Livermore, David M, Mikulska, Malgorzata, Viscoli, Claudio, Gyssens, Inge C, Kern, Winfried V, Klyasova, Galina, Marchetti, Oscar, Engelhard, Dan, Akova, Murat

“…Owing to increasing resistance and the limited arsenal of new antibiotics, especially against Gram-negative pathogens, carefully designed antibiotic regimens…”
Get full text

ESCMID guideline for the diagnosis and management of Candida diseases 2012: non‐neutropenic adult patients by Cornely, O. A., Bassetti, M., Calandra, T., Garbino, J., Kullberg, B. J., Lortholary, O., Meersseman, W., Akova, M., Arendrup, M. C., Arikan‐Akdagli, S., Bille, J., Castagnola, E., Cuenca‐Estrella, M., Donnelly, J. P., Groll, A. H., Herbrecht, R., Hope, W. W., Jensen, H. E., Lass‐Flörl, C., Petrikkos, G., Richardson, M. D., Roilides, E., Verweij, P. E., Viscoli, C., Ullmann, A. J.

“…Clin Microbiol Infect 2012; 18 (Suppl. 7): 19–37 This part of the EFISG guidelines focuses on non‐neutropenic adult patients. Only a few of the numerous…”
Get full text

Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients by De Waele, Jan J., Lipman, J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Udy, A. A., Starr, T., Wallis, S. C., Roberts, J. A.

“…Purpose Risk factors for β-lactam antibiotic underdosing in critically ill patients have not been described in large-scale studies. The objective of this study…”
Get full text

ESCMID guideline for the diagnosis and management of Candida diseases 2012: adults with haematological malignancies and after haematopoietic stem cell transplantation (HCT) by Ullmann, A. J., Akova, M., Herbrecht, R., Viscoli, C., Arendrup, M. C., Arikan‐Akdagli, S., Bassetti, M., Bille, J., Calandra, T., Castagnola, E., Cornely, O. A., Donnelly, J. P., Garbino, J., Groll, A. H., Hope, W. W., Jensen, H. E., Kullberg, B. J., Lass‐Flörl, C., Lortholary, O., Meersseman, W., Petrikkos, G., Richardson, M. D., Roilides, E., Verweij, P. E., Cuenca‐Estrella, M.

“…Clin Microbiol Infect 2012; 18 (Suppl. 7): 53–67 Fungal diseases still play a major role in morbidity and mortality in patients with haematological…”
Get full text

Leading infectious diseases problems in Turkey by Erdem, H., Akova, M.

“…Turkey has significant geographical and socio-economic differences throughout a vast area of the country. These characteristics affect the epidemiology of…”
Get full text

ESCMID guideline for the diagnosis and management of Candida diseases 2012: prevention and management of invasive infections in neonates and children caused by Candida spp by Hope, W. W., Castagnola, E., Groll, A. H., Roilides, E., Akova, M., Arendrup, M. C., Arikan‐Akdagli, S., Bassetti, M., Bille, J., Cornely, O. A., Cuenca‐Estrella, M., Donnelly, J. P., Garbino, J., Herbrecht, R., Jensen, H. E., Kullberg, B. J., Lass‐Flörl, C., Lortholary, O., Meersseman, W., Petrikkos, G., Richardson, M. D., Verweij, P. E., Viscoli, C., Ullmann, A. J.

“…Clin Microbiol Infect 2012; 18 (Suppl. 7): 38–52 Invasive candidiasis (IC) is a relatively common syndrome in neonates and children and is associated with…”
Get full text

ESCMID guideline for the diagnosis and management of Candida diseases 2012: diagnostic procedures by Cuenca‐Estrella, M., Verweij, P. E., Arendrup, M. C., Arikan‐Akdagli, S., Bille, J., Donnelly, J. P., Jensen, H. E., Lass‐Flörl, C., Richardson, M. D., Akova, M., Bassetti, M., Calandra, T., Castagnola, E., Cornely, O. A., Garbino, J., Groll, A. H., Herbrecht, R., Hope, W. W., Kullberg, B. J., Lortholary, O., Meersseman, W., Petrikkos, G., Roilides, E., Viscoli, C., Ullmann, A. J.

“…Clin Microbiol Infect 2012; 18 (Suppl. 7): 9–18 As the mortality associated with invasive Candida infections remains high, it is important to make optimal use…”
Get full text

Mixed fungaemia: an 18-year report from a tertiary-care university hospital and a systematic review by Gülmez, D., Alp, S., Gursoy, G., Ayaz, C.M., Dogan, O., Arikan-Akdagli, S., Akova, M.

“…While fungaemia caused by two or more different species of yeasts (mixed fungaemia, MF) is infrequent, it might be underestimated. This study aimed to…”
Get full text

Impact of the Inclusion of an Aminoglycoside to the Initial Empirical Antibiotic Therapy for Gram-Negative Bloodstream Infections in Hematological Neutropenic Patients: a Propensity-Matched Cohort Study (AMINOLACTAM Study) by Albasanz-Puig, A, Gudiol, C, Puerta-Alcalde, P, Ayaz, C M, Machado, M, Herrera, F, Martín-Dávila, P, Laporte-Amargós, J, Cardozo, C, Akova, M, Álvarez-Uría, A, Torres, D, Fortún, J, García-Vidal, C, Muñoz, P, Bergas, A, Pomares, H, Mercadal, S, Durà-Miralles, X, García-Lerma, E, Pallarès, N, Carratalà, J

“…To test the hypothesis that the addition of an aminoglycoside to a β-lactam antibiotic could provide better outcomes than β-lactam monotherapy for the initial…”
Get full text

ESCMID—an international Europe-based society committed to fostering cross-border collaboration and education to improve patient care by Poljak, M., Akova, M., Friedrich, A.W., Rodríguez-Baño, J., Sanguinetti, M., Tacconelli, E., Zinkernagel, A.

Get full text

Predictors of outcome in patients with severe sepsis or septic shock due to extended-spectrum β-lactamase-producing Enterobacteriaceae by Russo, A., Falcone, M., Gutiérrez-Gutiérrez, B., Calbo, E., Almirante, B., Viale, P.L., Oliver, A., Ruiz-Garbajosa, P., Gasch, O., Gozalo, M., Pitout, J., Akova, M., Peña, C., Cisneros, J.M., Hernández-Torres, A., Farcomeni, A., Prim, N., Origüen, J., Bou, G., Tacconelli, E., Tumbarello, M., Hamprecht, A., Karaiskos, I., de la Calle, C., Pérez, F., Schwaber, M.J., Bermejo, J., Lowman, W., Hsueh, P.-R., Mora-Rillo, M., Rodriguez-Gomez, J., Souli, M., Bonomo, R.A., Paterson, D.L., Carmeli, Y., Pascual, A., Rodríguez-Baño, J., Venditti, M.

“…•There are few data in the literature regarding sepsis or septic shock due to extended-spectrum β-lactamases (ESBL) strains.•The INCREMENT project is the…”
Get full text

ESCMID guideline for the diagnosis and management of Candida diseases 2012: developing European guidelines in clinical microbiology and infectious diseases by Ullmann, A. J., Cornely, O. A., Donnelly, J. P., Akova, M., Arendrup, M. C., Arikan‐Akdagli, S., Bassetti, M., Bille, J., Calandra, T., Castagnola, E., Garbino, J., Groll, A. H., Herbrecht, R., Hope, W. W., Jensen, H. E., Kullberg, B. J., Lass‐Flörl, C., Lortholary, O., Meersseman, W., Petrikkos, G., Richardson, M. D., Roilides, E., Verweij, P. E., Viscoli, C., Cuenca‐Estrella, M.

“…Clin Microbiol Infect 2012; 18 (Suppl. 7): 1–8 The process to develop a guideline in a European setting remains a challenge. The ESCMID Fungal Infection Study…”
Get full text