Search Results - "Akkus, Erman"
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A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats
Published in Cardiovascular diabetology (17-11-2018)“…Metabolic syndrome (MetS) is a prevalent risk factor for cardiac dysfunction. Although SGLT2-inhibitors have important cardioprotective effects in…”
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Clinical evaluation of DIAGNOVIR SARS-CoV-2 ultra-rapid antigen test performance compared to PCR-based testing
Published in Scientific reports (17-03-2023)“…Coronavirus Disease-19 (COVID-19) is a highly contagious infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The…”
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Crizotinib efficacy and safety in patients with advanced NSCLC harboring MET alterations: A real-life data of Turkish Oncology Group
Published in Medicine (Baltimore) (16-12-2022)“…Crizotinib is a multikinase inhibitor, effective in non-small cell lung cancer (NSCLC) harboring mesenchymal-epidermal transition (MET) alterations. Although…”
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Atezolizumab combined with chemotherapy in the first-line treatment of extensive-stage small cell lung cancer: a real-life data of the Turkish Oncology Group
Published in Journal of cancer research and clinical oncology (01-12-2022)“…Purpose Atezolizumab has been shown to be effective and safe in randomized trial in the first-line treatment of extensive-stage small cell lung cancer (SCLC)…”
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Types and Rates of COVID-19 Vaccination in Patients With Newly Diagnosed Microsatellite Stable and Instable Non-Metastatic Colon Cancer
Published in Curēus (Palo Alto, CA) (06-06-2024)“…Introduction Microsatellite instable (deficient mismatch repair, dMMR) colon cancer is associated with hypermutability and immune infiltration-activation…”
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Sweet’s syndrome under ipilimumab therapy and a brief comparison of the cases in literature
Published in Journal of oncology pharmacy practice (01-10-2020)“…Introduction Ipilimumab is an anti-cytotoxic T lymphocyte antigen 4 (CTLA-4) antibody. Ipilimumab has shown improvement in overall survival in patients with…”
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Trastuzumab ± Capecitabine Maintenance After the First-Line Treatment of HER2-Positive Advanced Gastric Cancer: Retrospective Observational Real-Life Data of Turkish Oncology Group
Published in Journal of gastrointestinal cancer (01-06-2022)“…Purpose In the ToGA trial for HER2-positive advanced gastric cancer, cisplatin plus fluoropyrimidine was given for 6 cycles; trastuzumab was given until…”
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Combination of trastuzumab and taxane-containing intensified chemotherapy in first-line treatment of HER2-positive advanced gastric cancer
Published in Tumori (01-10-2021)“…Purpose: Taxane-containing combinations are recommended for the first-line therapy of advanced gastric cancer. It is not known which chemotherapy regimen is…”
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Related molecular mechanisms of COVID-19, hypertension, and diabetes
Published in American journal of physiology: endocrinology and metabolism (01-06-2020)Get more information
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Fibroblast function in COVID-19
Published in Pathology, research and practice (01-03-2021)Get full text
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Asymptomatic pyuria and bacteriuria are not risk factors for urinary tract infection in women with type 2 diabetes mellitus initiated SGLT2 inhibitors
Published in International urology and nephrology (01-03-2024)“…Purpose Asymptomatic pyuria and bacteriuria are more prevalent in diabetic patients and may be associated with urinary tract infection (UTI). The aim of this…”
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Treatment approaches and survival outcomes in elderly colorectal cancer patients: a single-center comparative study
Published in Clinical & translational oncology (28-10-2024)“…Geriatric patients account for nearly half of new colorectal cancer (CRC) cases. This study compares clinicopathological features, treatments, outcomes, and…”
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Topical aloe vera for the treatment of cetuximab-related acneiform rash in colorectal cancer: A case report
Published in Journal of oncology pharmacy practice (01-03-2021)“…Introduction Colorectal cancer is one of the most common cancers in the world. Cetuximab is an epidermal growth factor receptor (EGFR) inhibitor which provides…”
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Advancements in platinum chemotherapy for metastatic castration-resistant prostate cancer: Insights and perspectives
Published in Cancer treatment reviews (01-11-2024)“…[Display omitted] •Platinum-based chemotherapy shows promise for mCRPC, offering a valuable option after traditional therapies fail.•Histopathological…”
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Efficacy and tolerability of vismodegib treatment in locally advanced and metastatic basal cell carcinoma: Retrospective real‐life data
Published in Dermatologic therapy (01-11-2021)“…The study aims to evaluate the vismodegib treatment in local advanced (laBCC) and metastatic (mBCC) basal cell carcinoma. The data of 29 patients were…”
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Thromboembolic risk in prostate cancer patients treated with PARP inhibitors: A systematic review and meta-analysis
Published in Critical reviews in oncology/hematology (01-06-2024)“…Poly (ADP-ribose) polymerase inhibitors (PARPi) have been associated with thrombotic events, although the association with thrombosis risk in different cancers…”
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Comment on “Potential role of ACE2 in coronavirus disease 2019 (COVID-19) prevention and management”
Published in Journal of translational internal medicine (25-09-2020)Get full text
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Glucagon‐like peptide‐1 receptor agonist treatment of high carbohydrate intake‐induced metabolic syndrome provides pleiotropic effects on cardiac dysfunction through alleviations in electrical and intracellular Ca2+ abnormalities and mitochondrial dysfunction
Published in Clinical and experimental pharmacology & physiology (01-01-2022)“…The pleiotropic effects of glucagon‐like peptide‐1 receptor (GLP‐1R) agonists on the heart have been recognised in obese or diabetic patients. However, little…”
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Glucagon-like peptide-1 receptor agonist treatment of high carbohydrate intake-induced metabolic syndrome provides pleiotropic effects on cardiac dysfunction through alleviations in electrical and intracellular Ca 2+ abnormalities and mitochondrial dysfunction
Published in Clinical and experimental pharmacology & physiology (01-01-2022)“…The pleiotropic effects of glucagon-like peptide-1 receptor (GLP-1R) agonists on the heart have been recognised in obese or diabetic patients. However, little…”
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