Search Results - "Akkers, Robert C."
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1
LPCAT1 controls phosphate homeostasis in a zinc-dependent manner
Published in eLife (17-02-2018)“…All living organisms require a variety of essential elements for their basic biological functions. While the homeostasis of nutrients is highly intertwined,…”
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A Hierarchy of H3K4me3 and H3K27me3 Acquisition in Spatial Gene Regulation in Xenopus Embryos
Published in Developmental cell (01-09-2009)“…Epigenetic mechanisms set apart the active and inactive regions in the genome of multicellular organisms to produce distinct cell fates during embryogenesis…”
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3
Performance of a novel melting curve-based qPCR assay for malaria parasites in routine clinical practice in non-endemic setting
Published in Malaria journal (22-06-2023)“…High-quality malaria diagnosis is essential for effective treatment and clinical disease management. Microscopy and rapid diagnostic tests are the conventional…”
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Characterization of genome-wide p53-binding sites upon stress response
Published in Nucleic acids research (01-06-2008)“…The tumor suppressor p53 is a sequence-specific transcription factor, which regulates the expression of target genes involved in different stress responses. To…”
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5
Nucleotide composition-linked divergence of vertebrate core promoter architecture
Published in Genome research (01-03-2011)“…Transcription initiation involves the recruitment of basal transcription factors to the core promoter. A variety of core promoter elements exists; however for…”
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ChIP-chip designs to interrogate the genome of Xenopus embryos for transcription factor binding and epigenetic regulation
Published in PloS one (21-01-2010)“…Chromatin immunoprecipitation combined with genome tile path microarrays or deep sequencing can be used to study genome-wide epigenetic profiles and the…”
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TBP paralogs accommodate metazoan- and vertebrate-specific developmental gene regulation
Published in The EMBO journal (05-09-2007)“…In addition to TATA‐binding protein (TBP), a key factor for transcription initiation, the metazoan‐specific TBP‐like factor TLF/TRF2 and the…”
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Estrogen-Receptor Loss and ESR1 Mutation in Estrogen-Receptor-Positive Metastatic Breast Cancer and the Effect on Overall Survival
Published in Cancers (30-08-2024)“…In patients with metastatic estrogen-receptor (ER)-positive HER2-negative breast cancer, the loss of ER expression and the mutation of -the gene encoding the…”
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Principles of nucleation of H3K27 methylation during embryonic development
Published in Genome research (01-03-2014)“…During embryonic development, maintenance of cell identity and lineage commitment requires the Polycomb-group PRC2 complex, which catalyzes histone H3 lysine…”
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Natural variation in Arabidopsis thaliana reveals shoot ionome, biomass, and gene expression changes as biomarkers for zinc deficiency tolerance
Published in Journal of experimental botany (15-06-2017)“…Zinc (Zn) is an essential nutrient for plants, with a crucial role as a cofactor for many enzymes. Approximately one-third of the global arable land area is Zn…”
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Chromatin immunoprecipitation analysis of Xenopus embryos
Published in Methods in molecular biology (Clifton, N.J.) (2012)“…Chromatin immunoprecipitation (ChIP) is a powerful technique to study epigenetic regulation and transcription factor binding events in the nucleus. It is based…”
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12
Erdheim Chester disease presenting as sclerosing mesenteritis
Published in Journal of hematopathology (01-03-2021)Get full text
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13
A Hierarchy of H3K4me3 and H3K27me3 Acquisition in Spatial Gene Regulation in Xenopus Embryos
Published in Developmental cell (15-09-2009)“…Epigenetic mechanisms set apart the active and inactive regions in the genome of multicellular organisms to produce distinct cell fates during embryogenesis…”
Get full text
Journal Article