Search Results - "Akkers, Robert C."

  • Showing 1 - 13 results of 13
Refine Results
  1. 1

    LPCAT1 controls phosphate homeostasis in a zinc-dependent manner by Kisko, Mushtak, Bouain, Nadia, Safi, Alaeddine, Medici, Anna, Akkers, Robert C, Secco, David, Fouret, Gilles, Krouk, Gabriel, Aarts, Mark Gm, Busch, Wolfgang, Rouached, Hatem

    Published in eLife (17-02-2018)
    “…All living organisms require a variety of essential elements for their basic biological functions. While the homeostasis of nutrients is highly intertwined,…”
    Get full text
    Journal Article
  2. 2

    A Hierarchy of H3K4me3 and H3K27me3 Acquisition in Spatial Gene Regulation in Xenopus Embryos by Akkers, Robert C., van Heeringen, Simon J., Jacobi, Ulrike G., Janssen-Megens, Eva M., Françoijs, Kees-Jan, Stunnenberg, Hendrik G., Veenstra, Gert Jan C.

    Published in Developmental cell (01-09-2009)
    “…Epigenetic mechanisms set apart the active and inactive regions in the genome of multicellular organisms to produce distinct cell fates during embryogenesis…”
    Get full text
    Journal Article
  3. 3

    Performance of a novel melting curve-based qPCR assay for malaria parasites in routine clinical practice in non-endemic setting by van Bergen, Kim J M, Stuitje, Antoine R, Akkers, Robert C, Vermeer, Henricus J, Castel, Rob, Mank, Theo G

    Published in Malaria journal (22-06-2023)
    “…High-quality malaria diagnosis is essential for effective treatment and clinical disease management. Microscopy and rapid diagnostic tests are the conventional…”
    Get full text
    Journal Article
  4. 4

    Characterization of genome-wide p53-binding sites upon stress response by Smeenk, Leonie, van Heeringen, Simon J, Koeppel, Max, van Driel, Marc A, Bartels, Stefanie J.J, Akkers, Robert C, Denissov, Sergei, Stunnenberg, Hendrik G, Lohrum, Marion

    Published in Nucleic acids research (01-06-2008)
    “…The tumor suppressor p53 is a sequence-specific transcription factor, which regulates the expression of target genes involved in different stress responses. To…”
    Get full text
    Journal Article
  5. 5

    Nucleotide composition-linked divergence of vertebrate core promoter architecture by van Heeringen, Simon J, Akhtar, Waseem, Jacobi, Ulrike G, Akkers, Robert C, Suzuki, Yutaka, Veenstra, Gert Jan C

    Published in Genome research (01-03-2011)
    “…Transcription initiation involves the recruitment of basal transcription factors to the core promoter. A variety of core promoter elements exists; however for…”
    Get full text
    Journal Article
  6. 6

    ChIP-chip designs to interrogate the genome of Xenopus embryos for transcription factor binding and epigenetic regulation by Akkers, Robert C, van Heeringen, Simon J, Manak, J Robert, Green, Roland D, Stunnenberg, Hendrik G, Veenstra, Gert Jan C

    Published in PloS one (21-01-2010)
    “…Chromatin immunoprecipitation combined with genome tile path microarrays or deep sequencing can be used to study genome-wide epigenetic profiles and the…”
    Get full text
    Journal Article
  7. 7

    TBP paralogs accommodate metazoan- and vertebrate-specific developmental gene regulation by Jacobi, Ulrike G, Akkers, Robert C, Pierson, Elisabeth S, Weeks, Daniel L, Dagle, John M, Veenstra, Gert Jan C

    Published in The EMBO journal (05-09-2007)
    “…In addition to TATA‐binding protein (TBP), a key factor for transcription initiation, the metazoan‐specific TBP‐like factor TLF/TRF2 and the…”
    Get full text
    Journal Article
  8. 8

    Estrogen-Receptor Loss and ESR1 Mutation in Estrogen-Receptor-Positive Metastatic Breast Cancer and the Effect on Overall Survival by Westenend, Pieter J, Meurs, Claudia J C, de Leeuw, Bertie, Akkers, Robert C

    Published in Cancers (30-08-2024)
    “…In patients with metastatic estrogen-receptor (ER)-positive HER2-negative breast cancer, the loss of ER expression and the mutation of -the gene encoding the…”
    Get full text
    Journal Article
  9. 9

    Principles of nucleation of H3K27 methylation during embryonic development by van Heeringen, Simon J, Akkers, Robert C, van Kruijsbergen, Ila, Arif, M Asif, Hanssen, Lars L P, Sharifi, Nilofar, Veenstra, Gert Jan C

    Published in Genome research (01-03-2014)
    “…During embryonic development, maintenance of cell identity and lineage commitment requires the Polycomb-group PRC2 complex, which catalyzes histone H3 lysine…”
    Get full text
    Journal Article
  10. 10

    Natural variation in Arabidopsis thaliana reveals shoot ionome, biomass, and gene expression changes as biomarkers for zinc deficiency tolerance by Campos, Ana Carolina A.L., Kruijer, Willem, Alexander, Ross, Akkers, Robert C., Danku, John, Salt, David E., Aarts, Mark G.M.

    Published in Journal of experimental botany (15-06-2017)
    “…Zinc (Zn) is an essential nutrient for plants, with a crucial role as a cofactor for many enzymes. Approximately one-third of the global arable land area is Zn…”
    Get full text
    Journal Article
  11. 11

    Chromatin immunoprecipitation analysis of Xenopus embryos by Akkers, Robert C, Jacobi, Ulrike G, Veenstra, Gert Jan C

    “…Chromatin immunoprecipitation (ChIP) is a powerful technique to study epigenetic regulation and transcription factor binding events in the nucleus. It is based…”
    Get more information
    Journal Article
  12. 12
  13. 13

    A Hierarchy of H3K4me3 and H3K27me3 Acquisition in Spatial Gene Regulation in Xenopus Embryos by Akkers, Robert C, Van Heeringen, Simon J, Jacobi, Ulrike G, Janssen-Megens, Eva M, Francoijs, Kees-Jan, Stunnenberg, Hendrik G, Veenstra, Gert Jan C

    Published in Developmental cell (15-09-2009)
    “…Epigenetic mechanisms set apart the active and inactive regions in the genome of multicellular organisms to produce distinct cell fates during embryogenesis…”
    Get full text
    Journal Article