Search Results - "Akireddy, Rao"

Comparison of acetylcholine receptor interactions of the marine toxins, 13-desmethylspirolide C and gymnodimine by Hauser, Terry A., Hepler, Christopher D., Kombo, David C., Grinevich, Vladimir P., Kiser, Melanie N., Hooker, Dawn N., Zhang, Jiahui, Mountfort, Douglas, Selwood, Andrew, Akireddy, S. Rao, Letchworth, Sharon R., Yohannes, Daniel

“…The interaction of 13-desmethylspirolide C (SPX-desMe-C) and gymnodimine with several nicotinic and muscarinic acetylcholine receptors was investigated…”
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Nonproteinogenic amino acids: an efficient asymmetric synthesis of ( S)-(−)-acromelobic acid and ( S)-(−)-acromelobinic acid by Adamczyk, Maciej, Akireddy, Srinivasa Rao, Reddy, Rajarathnam E

“…An efficient synthesis of ( S)-(−)-acromelobic acid ( 1 ) and ( S)-(−)-acromelobinic acid ( 2 ) is described via asymmetric hydrogenation protocol. Asymmetric…”
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Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs) by Strachan, Jon-Paul, Kombo, David C., Mazurov, Anatoly, Heemstra, Ronald, Bhatti, Balwinder S., Akireddy, Rao, Murthy, Srinivasa, Miao, Lan, Jett, John E., Speake, Jason, Bencherif, Merouane

“…We have synthesized a novel series of compounds, 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides, targeting both the α4β2 and α6/α3β2β3 nAChRs. Members of the…”
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Versatile synthesis of (+)-deoxypyridinoline, a biochemical marker for diagnosis of osteoporosis by Adamczyk, Maciej, Rao Akireddy, Srinivasa, Reddy, Rajarathnam E.

“…A versatile chiral synthesis of the bone collagen cross-link, (+)-deoxypyridinoline (Dpd, 1) was described starting from a 3-hydroxypyridine derivative ( 2)…”
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First Total Synthesis of (±)-3-Hydroxy-11-norcytisine: Structure Confirmation and Biological Characterization by Yohannes, Daniel, Hansen, Camilla P, Akireddy, Srinivasa Rao, Hauser, Terry A, Kiser, Melanie N, Gurnon, Nicholas J, Day, Cynthia S, Bhatti, Balwinder, Caldwell, William S

“…The first total synthesis of the natural product 3-hydroxy-11-norcytisine (1), structurally related to cytisine (2), a benchmark ligand at neuronal nicotinic…”
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Synthesis of 3,7-dihydroimidazo[1,2 a]pyrazine-3-ones and their chemiluminescent properties by Adamczyk, Maciej, Akireddy, Srinivasa Rao, Johnson, Donald D, Mattingly, Phillip G, Pan, You, Reddy, Rajarathnam E

“…A series of 3,7-dihydroimidazo[1,2 a]pyrazine-3-ones were prepared from 2-amino-3,5-dibromopyrazine. The concise synthesis of coelenterazine ( 5j ), in three…”
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Enantioselective Synthesis of (2-Pyridyl)alanines via Catalytic Hydrogenation and Application to the Synthesis of l-Azatyrosine by Adamczyk, Maciej, Akireddy, Srinivasa Rao, Reddy, Rajarathnam E

“…A novel method for the synthesis of (2-pyridyl)alanines 2a − b was developed by converting (2-pyridyl)dehydroamino acid derivatives 1a − b to the corresponding…”
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Transformation of Vitamin B6 to (+)-Deoxypyridinoline, a useful Biochemical Marker for Diagnosis of Bone Diseases by Adamczyk, Maciej, Akireddy, Srinivasa Rao, Reddy, Rajarathnam E.

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Asymmetric synthesis of ( S)-(−)-acromelobinic acid by Adamczyk, Maciej, Akireddy, Srinivasa Rao, Reddy, Rajarathnam E.

“…A total synthesis of ( S)-(−)-acromelobinic acid 2, which was isolated from clitocybe acromelalga, was achieved via an asymmetric hydrogenation protocol…”
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Synthesis of hapten–phosphoramidites from 2′-deoxyuridine by Adamczyk, Maciej, Akireddy, Srinivasa Rao, Mattingly, Phillip G, Reddy, Rajarathnam E

“…A total of 11 novel phosphoramidites, 3a– d , 4a– d and 14a– c were prepared from 2′-deoxyuridine functionalized at 5 and 6-position of the pyrimidine ring…”
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An Efficient Enantioselective Synthesis of (S)-(−)-Acromelobic Acid by Adamczyk, Maciej, Akireddy, Srinivasa Rao, Reddy, Rajarathnam E

“…A highly efficient enantioselective synthesis of (S)-(−)-acromelobic acid (1) was achieved via asymmetric hydrogenation of dehydroamino acid derivative (3)…”
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Transformation of Vitamin B 6 to (+)-Deoxypyridinoline, a useful Biochemical Marker for Diagnosis of Bone Diseases by Adamczyk, Maciej, Akireddy, Srinivasa Rao, Reddy, Rajarathnam E.

“…A versatile chiral synthesis of the cross-link (+)-deoxypyridinoline (Dpd, 2) was achieved starting from vitamin B 6 ( 7). The key steps in the synthesis of…”
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Hapten-phosphoramidites based on 6-[(2 E)- N-(hexyl)prop-2-enamidyl]-2′-deoxyuridine by Adamczyk, Maciej, Akireddy, Srinivasa Rao, Mattingly, Phillip G, Reddy, Rajarathnam E

“…Novel hapten-phosphoramidites 11a– c were prepared from 2′-deoxyuridine ( 2 ) by functionalization at the 6-position and subsequent conjugation with…”
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